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Neanderthal ancestry may lower defenses against common DNA viruses in people today

Researchers have found surprising links that show that Neanderthal ancestry influences our immune system today in ways more nuanced than previously recognized. Their work is published in the journal Genome Biology and Evolution.

Viruses account for an estimated 10–20% of the global disease burden. Many DNA viruses can persist in the body for a lifetime, and virus load varies greatly even among people without symptoms. Throughout human history, they have posed persistent and rapidly evolving threats, placing strong adaptive pressure on our immune system.

Previous research has shown that many genetic variants involved in immunity bear the marks of these evolutionary battles—including signatures of natural selection and contributions from interbreeding with archaic humans.

While Neanderthal ancestry has previously been associated with beneficial effects in RNA virus defense, the new study highlights a contrasting trend for DNA viruses.

Because of past admixture with archaic humans, around 2% of the genome of present-day non-Africans is composed of Neanderthal DNA and an additional 2–4% of people in Oceania of Denisovan ancestry. These introgressed sequences have shaped many biological traits, including immunity. But their role in defenses against DNA viruses has remained largely unexplored.

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Scientists Found 71 Genetic Fingerprints of Human History. Not All of Them Make Sense.

Homo sapiens are one species. There are no subspecies of humans, and our last relatives in the genus Homo went extinct around 40,000 years ago. But what explains how similar we humans are to each other? And more importantly, what genetic variants make different human populations and individuals so unique?

Some of the things we inherit in our genes are completely random. This is known as genetic drift, a phenomenon that happens because some individuals leave behind more offspring than others do. Their genes are more likely to be spread throughout the population, but it’s not because natural selection decided that those genes necessarily offer any added benefits. In fact, it’s even possible that a few of those genes are detrimental. Genetic drift is part of evolution and something that defines the genetic fingerprint of a specific group, but it doesn’t work by promoting adaptations that will help our species in the future.

Genetic drift isn’t exclusive to humans, but a team of researchers from the Institute of Statistical Science in Taipei, Taiwan, created an algorithm to figure out how it affects the frequency of alleles in human populations. Alleles are alternative versions of a given gene that come about through mutations. The team accessed data from the 1,000 Genomes Project, a database of single nucleotide polymorphisms (SNPs), which are common genetic variations caused by a difference in a single nucleotide within a DNA sequence. The researchers then used their algorithm to analyze recurring patterns of alleles in populations from different continents, as well as in groups within those populations.

“At the global scale, genetic differences between subjects faithfully reflect the well-known history of human population migration and mixing,” they said in a study recently published in Scientific Reports. “In contrast, when examining the allele frequency patterns of individual loci, we discovered many minor yet non-negligible…evolutionary trajectories in the human genome.”

Out of 78 million SNPs, the researchers found 71 patterns that tell the ancient history of how allele frequencies ended up being arranged in particular ways among various groups. It was hardly surprising that over 90% of such variants occurred with more or less the same frequency no matter what continent the population was from. The locations of most allele frequency patterns are scattered throughout chromosomes and are usually found together in “hot spots.” These narrow segments of DNA are linked to gene functions and observable phenotypical (body) traits.

Then the team used what they called a local ancestry inference algorithm to look deep into chromosomes and determine what ancestral groups an individual is descended from. The results from this algorithm were then checked against data from 1,000 Genomes and Human Genome Population Diversity (HGPD) data. It turned out that most allele patterns observed were synonymous with simulations that highlight the randomness of genetic drift. But there were also minor differences that suggest drift isn’t the only evolutionary process influencing the genetic profile of an individual or population.

Many findings were consistent with the migration of human ancestors out of Africa and into Europe, East Asia, and South Asia. Allele frequencies in African populations were found to be distinct from those of Eurasians in 1.9 million locations on their DNA. The separation of African and East Asian populations from populations in Europe and South Asia was evidenced by variants in 570,000 locations. This reflects the known history of human migration, which has Eurasians as the first to break from their African ancestors and trek through Europe and East Asia. South Asian populations arose from admixture between groups from Central Asia and migrants who first traveled from West to East Asia before heading south.

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Stone Age humans built complex grass beds at Border Cave 200,000 years ago, study finds

Border Cave sits high in the Lebombo Mountains along the border of present-day South Africa and Eswatini. Archaeologists have excavated the rock shelter since the 1930s, though recent work has revealed unusual preservation of organic materials, including ancient grass bedding. Researchers from the University of the Witwatersrand examined the deposits at a microscopic level and identified six different bedding microfacies, or microscopic sediment patterns linked to different types of bed construction and maintenance.

Only a few African Stone Age sites have produced bedding remains studied in such detail. Earlier microscopic work at Sibhudu Cave and Diepkloof Rock Shelter provided much of the current understanding of ancient bedding practices. The new study greatly expands the sample from Border Cave and shows a wider range of preserved bedding structures than previously known.

Some of the newly identified microfacies closely resemble bedding types from the other South African sites. Others appear unique to Border Cave. The differences include variations in ash content, the arrangement of plant remains, and signs of trampling or burning. Researchers suggest these patterns reflect differences in how people maintained their living spaces or the types of plants selected for bedding.

The study found repeated evidence that people often built beds on layers of ash. In many cases, bedding materials rested directly above ash deposits or mixed with ash-rich sediments. Researchers believe ash may have helped keep sleeping areas dry and warm while also discouraging insects. Earlier studies at Border Cave proposed a similar function.

The evidence does not always show whether people intentionally spread fresh ash before laying down bedding or reused ash already present on the cave floor. Some ash deposits appear thick and concentrated, while others form thinner scattered layers. Still, the repeated association between ash and bedding suggests this practice formed a regular part of cave life for thousands of years.

Microscopic analysis also revealed signs of repeated maintenance. Some bedding layers had been refreshed with new plant material, trampled by human activity, and partially burned several times. One especially well-preserved “grass mat” from younger deposits contained several overlapping layers of dried and charred plant remains. Researchers describe this as the first detailed microscopic study of such a preserved Stone Age grass mat.

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Police confirm body is missing Taos woman, LANL worker

New Mexico State Police confirmed Saturday night that human remains discovered off Rio Chiquito Road southeast of Taos belong to Melissa Casias, the missing Ranchos de Taos woman and Los Alamos National Laboratory worker who disappeared last June.

The single lane dirt road — Forest Road 437 — is accessible from N.M. 518 in Talpa, where security camera footage captured the last known sighting of Casias on June 26 of last year. Rio Chiquito Road extends deep into the Carson National Forest and provides access to the Garcia Park recreation area and several trails.

The body was discovered by a hiker in the McGaffey Ridge area of the national forest.

The Office of the Medical Investigator positively identified the deceased individual as Casias, however the cause and manner of death have not yet been determined, according to a state police press release. Police said a handgun was found “alongside the remains.”

The remains will undergo “further anthropological examination” by the medical investigator, according to state police, who “extend their deepest condolences to the Casias and Mondragon families during this difficult time.”

Jazmin McMillen, Casias’ niece, posted an official statement from the family on a Facebook page dedicated to finding the missing wife and mother. 

“We confirm that the remains found in Rio Chiquito are Melissa,” the post states. “There will be more information to come but what we can tell you now is she was located in an area previously searched. This is a lot to process, our hearts are heavy and we fully intend to continue to pursue answers for justice.”  

An investigation into the circumstances of Casias’ disappearance and her death is ongoing.

Casias, who lived with her husband in Ranchos de Taos, was reported missing after her daughter, Sierra Casias, came home from work and discovered her mother’s keys, wallet, and work and personal cell phones — both wiped of data — inside the house. Her mother’s car was parked outside the home and the front door was locked. Melissa Casias was an administrative assistant at LANL, where her husband, Mark Casias, also worked.

Her disappearance drew national media attention and has been featured on the Crime Junkie podcast, which reported the discovery of the human remains in a social media post Friday evening (May 29).

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Federal Agents Arrest Karen Bass-Linked “Peace Ambassador” — Convicted Murderer and Active 18th Street Gang Member Was Being Paid with Taxpayer Dollars Through NGO Program

Federal law enforcement just exposed another jaw-dropping failure of Los Angeles’ radical “reimagine public safety” experiment under Mayor Karen Bass.

Michael Angel Alvarez, 41, aka “Diablo,” a convicted first-degree murderer and alleged active 18th Street gang member, was arrested by federal agents after being paid over $58,000 last year by a city-contracted nonprofit to serve as a so-called “Peace Ambassador.”

The arrest went down on May 18 near MacArthur Park. LAPD officers responding to a stolen vehicle call detained Alvarez. He reportedly told them he worked for Mayor Karen Bass’s Crisis Response Team (“CRT”).

Take a look at the absolute insanity of this operation, according to the DOJ:

  • The Suspect: A hardened gangster convicted of first-degree murder in 2002. He was sentenced to 50 years to life but was cut loose early by California’s broken justice system. Federal authorities state he is still an active 18th Street gang member who was recently caught on jailhouse phone calls plotting to assault people who broke gang rules.
  • The Scam: Alvarez didn’t just sneak onto the payroll. He was funded through “Healing Urban Barrios” (HUB), a Lincoln Heights-based Non-Governmental Organization (NGO) that secured a lucrative contract with the city.
  • The Taxpayer Cost: Under the guise of a “Peace Ambassador program”—which the city website laughably describes as an initiative to “prevent violence before it starts”—the city of Los Angeles approved a staggering $450,000 from its general fund to flow into this NGO between 2024 and 2027.
  • The Payout: In 2025 alone, this taxpayer-funded NGO handed Alvarez $58,156 to patrol the streets as an unarmed “peacekeeper.”

Federal authorities noted that during the search of “Diablo’s” vehicle, they discovered top-tier, military-grade body armor plates in his trunk — marketed as the highest level of protection available on the civilian market.  Apparently, being a “Peace Ambassador” requires a lot of tactical gear when you are actively running with a cartel-linked street gang.

If convicted, Alvarez would face a statutory maximum sentence of five years in federal prison.

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State of New York Hearing: Reparations for Slavery Only Form of ‘True Justice’

Black New Yorkers attending a state commission studying remedies for racism said they were due cash reparations for slavery and other past injustices.

The New York “State Community Commission on Reparations Remedies” hearing follows Gov. Kathy Hochul signing a bill in 2023 for a commission to study slavery in New York state and examine various forms of compensation.

“We need $800,000 for each foundational black American. That’s simple,” Aubrey Muhammud, one of the attendees, told Fox News Digital. “That’s — in New York — that’s about the cost of living that’ll get you a home or a small business or for you to recover from any financial duress.”

New York joins several other Democratic run states and local municipalities looking to issue reparations in some form.

The Chicago suburb of Evanston, Illinois went as far as paying $25,000 in cash to Black residents to address past racial housing discrimination, according to Fox’s coverage of the controversial issue Saturday.

San Francisco enacted legislation earlier this year establishing official reparations of $5 million to each eligible Black residents. However, facing a $1 billion city budget deficit, the measure contains no taxpayer-allocated funds or guaranteed cash payouts.

New York’s public hearing allowed for residents to relate their experiences to the commission, reportedly in an effort to examine past discriminatory policies and slavery in the United States.

“Certainly grateful that you all came up here today to enjoy and participate and lend your voice to this public hearing. Our theme today is truth before repair,” commissioner Seanelle Hawkins told the audience.

Who exactly would get payments is a matter of concern to some attendees.

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Watch How a Hijab-Wearing AOC Is Treated by a Muslim Male Audience as She Tries Pandering to Them During Eid Celebration in New York City

A Muslim male crowd gave AOC a rude welcome as she attempted to pander to them at a prominent Muslim holiday celebration in New York City.

As The Gateway Pundit previously reported, AOC was seen wearing a hijab at an Eid Celebration in New York City, which was attended by Muslim men.

Addressing a crowd on Wednesday, AOC called on people to “renew our commitments to one another” so together they “can bring light into the darkness.”

Despite claiming to be a feminist who wants to dismantle the patriarchy, the hijab is widely seen as a symbol of female repression intended to prevent Islamic women from attracting the attention of men.

Despite AOC’s pandering, the Muslim audience was unmoved.

Instead of listening, the attendees ignored what she was saying and started speaking among themselves.

In addition, the background noise completely muffled her speech.

So much disrespect for AOC.

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CDC expands Ebola screenings to New York’s JFK airport

The Centers for Disease Control and Prevention has expanded its passenger screening for Ebola to John F. Kennedy International Airport in New York.

The federal agency said the expansion of its around-the-clock Port Health Protection system went into effect at Kennedy airport Thursday night. 

 The CDC also said Kennedy previously conducted enhanced public health entry screening and has established operational procedures in place.

The enhanced screening” is also now underway at Washington Dulles International Airport, Hartsfield-Jackson Atlanta International Airport and the George Bush Intercontinental Airport, in Houston, for air passengers arriving from the Democratic Republic of the Congo, South Sudan and Uganda. 

“Public health entry screening serves as one component of CDC’s layered public health approach, which also includes overseas exit screening, airline illness reporting, and post-arrival public health monitoring,” the CDC said in a post on X.

The State Department issued a travel advisory recently, instructing all U.S.-bound American citizens and lawful permanent residents who have been in the DRC, Uganda or South Sudan within 21 days of arrival in the U.S. to go through the “enhanced public health screening” carried out by the CDC and U.S. Customs and Border Protection.

The screenings come ahead of the 2026 FIFA World Cup, which is scheduled to take place in the United States, Canada and Mexico next month. The first match will take place in Mexico City on June 11.

The United States has not seen an Ebola case so far, though one American tested positive for the virus while overseas and is being treated in Germany.

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Social Media Users LIGHT UP James Talarico After Hearing the Woke Four-Word Term He Uses to Describe Women

Texas Democrat U.S. Senate candidate James Talarico managed to go viral for all the wrong reasons on Friday after a SuperPAC uncovered some old clips of him using a weird term to describe women.

Any normal person knows that there are two sexes: male and female. In addition, the terms men and women are used to describe those with male and female body parts.

Talarico, though, is anything but normal. It turns out he has a bizarre four-word term to describe the female race: neighbors with a uterus.

The Lone Star Liberty PAC, which supports Texas Attorney General Ken Paxton, released two clips of Talarico saying exactly this.

“Every one of our neighbors with a uterus became the property of the state,” Talarico says to a church audience in the first clip.

“Our neighbors with a uterus need to be able to control their own bodies,” he says in the second clip.

X users quickly lit up Talarico for not being able to use the term woman to describe the female

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3 Months of Trump’s Disastrous Iran War Has Cost US Consumers $60 Billion in Extra Energy Costs​

 Americans have made clear since President Donald Trump joined Israel in beginning an unprovoked war on Iran that they view the conflict-of-choice as damaging to their financial well-being—and that they blame the president for the higher cost of fuel since the war started in February.

On Friday, Moody’s Analytics put an exact number on the heightened financial anxiety families across the country have been feeling over the past three months as Iran’s closure of the Strait of Hormuz has sent fuel prices soaring: $447.19.

That’s how much the average US household has had to additionally spend on fuel-related expenses since Trump and Israeli Prime Minister Benjamin Netanyanu launched their attack on February 28, Moody’s told CNBC.

Altogether, Americans have spent a total of nearly $60 billion on gas, airline fares, and other related costs as the strait, a key shipping route for oil, has remained effectively closed.

According to AAA, the average price of a gallon of regular gas stands at $4.39—up close to 50% since early March. Diesel now costs $5.52 per gallon, forcing consumers to pay $20 billion more in additional expenses on groceries and other goods.

“The economy isn’t just soft, it’s struggling,” Mark Zandi, Moody’s chief economist, said Thursday. “The Iran war needs to end, and the Strait of Hormuz needs to be reopened soon, or recession will become more likely than not.”

As CNBC reported Friday, “higher energy costs can force consumers to raid their savings and lean more on debt to cover expenses.”

Trump flatly said earlier this month that he doesn’t consider Americans’ financial situation “even a little bit” when it comes to the war on Iran, while National Economic Council Director Kevin Hassett posited earlier this week that Americans are “spending more money” not because higher prices are forcing them to but because they’re “very, very optimistic about the state of the economy.” He also bragged recently that “credit card spending is through the roof”—a sign several observers took not as a positive omen for the economy but as a sign that families are being forced to take on debt to pay for gas and other essentials.

Zandi provided a reality check Friday.

“Unless the war ends soon, financially pressed consumers will have no option but to turn more cautious in their spending, threatening the already soft economy,” he told CNBC, warning that families could end up spending nearly $2,000 extra on fuel-related costs if the war continues reaches the one-year mark.

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