GMO tomato as edible COVID vaccine? Mexican scientists work to make it a reality

While large companies and public sector consortiums in the United States, Canada, China and Europe are running at full speed to develop a vaccine grown in genetically modified (GM) tobacco plants, a research group at a Mexican university is working toward the same objective, but with a different and innovative strategy. They are using bioinformatics and computational genetic engineering to identify candidate antigens for a vaccine that can be expressed in tomato plants. Eating the fruit from these plants would then confer immunity against COVID-19.

At the time I write these lines, there are already more than 3.6 million people reportedly infected by the COVID19 pandemic and some 252,000 deaths globally. In the US, which has the world’s highest rate of infection, COVID-19 deaths have surpassed deaths from cancer, coronary heart disease and even influenza/pneumonia in just the few  months since the novel coronavirus arrived.

This critical situation has led the entire world to embark on a real race to develop a vaccine that immunizes the population against this new strain of coronavirus, which apparently emerged in the autumn of 2019 in China. So far, more than 100 vaccines are being investigated for COVID-19 by universities, public research centers and especially private companies. Some are already under clinical trial.

The approaches used for their production don’t differ much from the ones classically used in vaccines, where the antigens — a compound of the pathogen used to generate immunity in the patient — can be the inactivated virus, as well as the genetic material or a virus protein, which is grown on a large scale in chicken eggs, mammalian/insect cell tissue or genetically modified microorganisms.

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Scientists obtain magnetic nanopowder for 6G technology

Material scientists have developed a fast method for producing epsilon iron oxide and demonstrated its promise for next-generation communications devices. Its outstanding magnetic properties make it one of the most coveted materials, such as for the upcoming 6G generation of communication devices and for durable magnetic recording. The work was published in the Journal of Materials Chemistry C, a journal of the Royal Society of Chemistry.

Iron oxide (III) is one of the most widespread oxides on Earth. It is mostly found as the mineral hematite (or alpha iron oxide, α-Fe2O3). Another stable and common modification is maghemite (or gamma modification, γ-Fe2O3). The former is widely used in industry as a red pigment, and the latter as a magnetic recording medium. The two modifications differ not only in crystalline structure ( alpha-iron oxide has hexagonal syngony and gamma-iron oxide has cubic syngony) but also in magnetic properties.

In addition to these forms of iron oxide (III), there are more exotic modifications such as epsilon-, beta-, zeta-, and even glassy. The most attractive phase is epsilon iron oxide, ε-Fe2O3. This modification has an extremely high coercive force (the ability of the material to resist an external magnetic field). The strength reaches 20 kOe at room temperature, which is comparable to the parameters of magnets based on expensive rare-earth elements. Furthermore, the material absorbs electromagnetic radiation in the sub-terahertz frequency range (100-300 GHz) through the effect of natural ferromagnetic resonance.The frequency of such resonance is one of the criteria for the use of materials in wireless communications devices—the 4G standard uses megahertz and 5G uses tens of gigahertz. There are plans to use the sub-terahertz range as a working range in the sixth generation (6G) wireless technology, which is being prepared for active introduction in our lives from the early 2030s.

The resulting material is suitable for the production of converting units or absorber circuits at these frequencies. For example, by using composite ε-Fe2O3 nanopowders it will be possible to make paints that absorb electromagnetic waves and thus shield rooms from extraneous signals, and protect signals from interception from the outside. The ε-Fe2O3 itself can also be used in 6G reception devices.

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US cops served over 20,000 ‘invasive’ geofence warrants targeting users by location data in last 3 years, Google report shows

Google has revealed that over a quarter of all data request warrants it gets from US authorities involve identifying people by location history. These orders, which pinpoint devices near a crime scene, have been called “invasive.”

The so-called ‘geofence warrants’ allow law enforcement agencies to specify area and timeframe and have the tech giant gather information, including names and other details, about persons of interest in that window – from location information recorded by apps and services like Google Maps.

As part of its latest transparency report, the tech giant on Thursday revealed that it received more than 20,000 geofence warrants in the US between 2018 and 2020. It was the first time Google disclosed the volume of these controversial requests, having resisted demands to do so in the past.

Noting that these warrants are only “one subcategory” of the search warrant requests the company gets, Google noted it had “seen a rise” in the number of warrants ordering it to identify users by location info since 2018. That year, it received 982 geofence warrants, and the figure spiked to 11,554 in 2020.

As well, the vast majority of such warrants – to the tune of nearly 96% – are obtained by local and state law enforcement bodies, while federal agencies account for the remainder. Authorities in California made the most information requests between the years specified in the report.

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The Internet of Bodies Will Change Everything, for Better or Worse

Ross Compton was there when a fire ravaged his $400,000 home in Middletown, Ohio, in September 2016. Fortunately, Compton told investigators, he was able to stuff a few bags with several possessions—including the charger for an external heart pump he needed to survive—before shattering a window with his cane and escaping.

But as the smoke cleared, police began to suspect that Compton’s story was a fabrication.

His statements were inconsistent. The rubble smelled of gasoline. And it seemed implausible that someone fleeing a burning house—especially someone with a medical condition like Compton’s—could execute such a complex escape plan.

Eventually, investigators were able to indict Compton on felony charges of aggravated arson and insurance fraud. Their star witness? His pacemaker.

Police obtained a warrant to retrieve data on Compton’s heart activity before, during, and after the fire. After reviewing this information, a cardiologist concluded that it was “highly improbable” Compton would’ve been able to escape the flames so quickly, while lugging so many belongings.

Compton pleaded not guilty. His attorney argued that the pacemaker data should be thrown out; including it would violate doctor-patient privilege and Compton’s constitutional right to privacy, the lawyer said.

The case was strange, arguably sad, and fraught with difficult questions. Regardless of whether Compton really torched his house, should a life-saving device inside someone’s body be part of a case that might put them behind bars?

We may not know the answer for some time. Compton passed away in July at the age of 62, leaving his case—and whatever precedent it might have set—unresolved.

This may seem like a one-of-a-kind chain of events, an aberration. But as industries usher in a new era of devices that track personal information by leveraging the internet and the human body in equal measure, it won’t be the last.

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Seeing the future: the bionic eye

Those of us with healthy vision often take our sight for granted. From admiring masterpieces at the art gallery to being able to find the vegemite in the fridge, we rarely consider how different our lives would be if our vision was impaired. But reduced sight is a reality for more than half a million Australians, who currently experience blindness or low vision in a manner that affects their daily functioning.

The development of a bionic eye is therefore exciting technology. As with other medical bionic devices, however, it is not suitable for everyone. At least, not yet.

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Scientists Grew Stem Cell ‘Mini Brains’. Then, The Brains Sort-of Developed Eyes

Mini brains grown in a lab from stem cells have spontaneously developed rudimentary eye structures, scientists report in a fascinating new paper.

On tiny, human-derived brain organoids grown in dishes, two bilaterally symmetrical optic cups were seen to grow, mirroring the development of eye structures in human embryos. This incredible result will help us to better understand the process of eye differentiation and development, as well as eye diseases.

“Our work highlights the remarkable ability of brain organoids to generate primitive sensory structures that are light sensitive and harbor cell types similar to those found in the body,” said neuroscientist Jay Gopalakrishnan of University Hospital Düsseldorf in Germany.

“These organoids can help to study brain-eye interactions during embryo development, model congenital retinal disorders, and generate patient-specific retinal cell types for personalized drug testing and transplantation therapies.”

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Will $500M for Smart Cities in Historic US Senate Spending Bill Fund Biometric Surveillance?

Half a billion dollars was written into the $1.2 trillion infrastructure bill passed Wednesday by the U.S. Senate to pay cities to experiment with technologies for ‘Strengthening Mobility and Revolutionizing Transportation,’ which could include remote biometric systems, sensors and drones.

Reaction to the inclusion was rapid. The Intercept spoke with a senior staff attorney of the Electronic Frontier Foundation who said the ‘SMART’ money will buy more surveillance using facial recognition. The industry has yet to convince critics alleging face biometrics introduce racial and gender bias and misuse by law enforcement of the technology’s safety.

Also of concern is how this technology, if not the funding, will become tangled with relevant military programs as has happened with other software and hardware being deployed to monitor and quell dissent.

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Healthcare professionals app Doximity promises crackdown after doctors are accused of sharing “misinformation”

Doctors who take to social media to discuss their opposition to various COVID measures are facing calls for censorship from media outlets.

CNBC says it discovered plenty of vaccine skeptic statements on Doximity, a doctor-to-doctor networking site. While the reports shared on the app are from well-known news organizations and scientific journals, the comments, CNBC says, appear to be full of “misinformation” about vaccination safety, mask use, and natural immunity, among other things.

Dr Paul Malarik, a retired psychiatrist, spends up to 50 hours a month in pop-up clinics near his home in San Luis Obispo, California, helping to deliver COVID-19 vaccines. According to him, when he logs onto Doximity and sees vaccine skeptic remarks, he’s particularly disturbed.

Doximity is only open to healthcare professionals in the United States, and members must be verified before they can join. No one may post anonymously on the site.

It has long been branded as “LinkedIn for doctors,” had its stock market debut in June and quickly rose to a market valuation of $10 billion. According to the company’s IPO prospectus, it has 1.8 million members, including 80% of doctors. They utilize the site to remain in touch with one another, discuss research, keep up with industry news, and securely interact with patients.

Doximity likewise doesn’t let users publish their articles or stories; instead, it curates content from medical and scientific journals as well as mainstream news. Each user receives a personalized feed of aggregated material depending on their choices, such as their field of medical practice.

Members of Doximity may comment on articles, which is where the alleged “misinformation” and “conspiracy theories” appear to thrive, according to CNBC.

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Scanning your iPhone for Pegasus, NSO Group’s malware

In collaboration with more than a dozen other news organizations The Guardian recently published an exposé about Pegasus, a toolkit for infecting mobile phones that is sold to governments around the world by NSO Group. It’s used to target political leaders and their families, human rights activists, political dissidents, journalists, and so on, and surreptitiously download their messages/photos/location data, record their microphone, and otherwise spy on them. As part of the investigation, Amnesty International wrote a blog post with their forensic analysis of several compromised phones, as well as an open source tool, Mobile Verification Toolkit, for scanning your mobile device for these indicators. MVT supports both iOS and Android, and in this blog post we’ll install and run the scanner against my iOS device.

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