Psychedelic drugs were used by ancient man, new study shows

Researchers have found evidence of drug use during Bronze Age ceremonies.

Analysis of strands of human hair from a burial site on the Spanish island of Menorca indicates ancient human civilisations used hallucinogenic drugs derived from plants.

The findings are the first direct evidence of ancient drug use in Europe, which may have been used as part of ritualistic ceremonies, researchers say.

Researchers detected scopolamine, ephedrine and atropine in three replicated hair samples.

Atropine and scopolamine are naturally found in the nightshade plant family and can induce delirium, hallucinations and altered sensory perception.

Ephedrine is a stimulant derived from certain species of shrubs and pines which can increase excitement, alertness and physical activity.

Elisa Guerra-Doce, from the Universidad de Valladolid in Spain, and colleagues examined hair from the Es Carritx cave, which was first occupied around 3,600 years ago.

Writing in the Scientific Reports journal, the authors said: “Interestingly, the psychoactive substances detected in this study are not suitable for alleviating the pain involved in severe palaeopathological conditions attested in the population buried in the cave of Es Carritx, such as periapical abscesses, severe caries and arthropathies.

“Considering the potential toxicity of the alkaloids found in the hair, their handling, use and applications represented highly specialised knowledge. This knowledge was typically possessed by shamans, who were capable of controlling the side-effects of the plant drugs through an ecstasy that made diagnosis or divination possible.”

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NBA Takes Steps to Ease Cannabis Restrictions: This Week in Cannabis Investing

The NBA took a major step forward this week by allowing players to invest in and promote cannabis brands. 

Michele Roberts, a former executive director of the NBA Players Association and now a member of the board of directors at Cresco Labs (CRLBF(opens in new tab)), previously predicted that NBA would consider changing its policies around cannabis. 

As of the terms listed in the leagues’ new collective bargaining agreement, cannabis will also be removed from the banned substances list for players. This is a welcome change for a cannabis industry seeking additional sources of capital while it continues to erode the old-world stigmas created by previous generations. 

We’ve seen a number of professional athletes getting involved in the cannabis industry after their sports careers. They are a group that is keen on the benefits cannabis provides for pain and inflammatory management, and many are also passionate about making a difference. Former NBA veteran Al Harrington’s Viola Brands(opens in new tab) immediately comes to mind as a trailblazer here. We’re excited to welcome more athletes, especially those as passionate about building their brands and business ventures as they are about their active profession.

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Michigan Republican admits to taking bribes while overseeing state medical cannabis board

A former Michigan House speaker was indicted along with two lobbyists and a medical marijuana business owner as part of a bribery scheme.

Rick Johnson, the Republican former House speaker and chairman of the state medical marijuana licensing board from 2017 to 2019, was charged with accepting bribes, while registered lobbyists Brian Pierce and Vincent Brown were charged with conspiracy to commit bribery and John Dalaly, who had sought a business license, was charged with payment of bribes, reported the Detroit Free Press.

“Unfortunately, a small percentage (of public officials) abuse the public trust,” said James Tarasca, special agent in charge of the FBI in Michigan. “Public corruption is a top criminal priority for the FBI. Public corruption erodes confidence and undermines the strength of our democracy.”

James Totten, the U.S. attorney for the Western District of Michigan, said a five-year investigation determined that Johnson was the “heart” of the bribery scheme that involved more than $100,000 in cash payments from companies and lobbyists seeking licenses from the board he led.

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Secret limits to stop ‘suspicious’ Xanax and Adderall orders are forcing some legitimate patients to scramble

Patients diagnosed with conditions like anxiety and sleep disorders have become caught in the crosshairs of America’s opioid crisis, as secret policies mandated by a national opioid settlement have turned filling legitimate prescriptions into a major headache.

In July, limits went into effect that flag and sometimes block pharmacies’ orders of controlled substances such as Adderall and Xanax when they exceed a certain threshold. The requirement stems from a 2021 settlement with the US’s three largest drug distributors — AmerisourceBergen Corp., Cardinal Health Inc. and McKesson Corp. But pharmacists said it curtails their ability to fill prescriptions for many different types of controlled substances — not just opioids.

Independent pharmacists said the rules force them come up with creative workarounds. Sometimes, they must send patients on frustrating journeys to find pharmacies that haven’t yet exceeded their caps in order to buy prescribed medicines.

“I understand the intention of this policy is to have control of controlled substances so they don’t get abused, but it’s not working,” said Richard Glotzer, an independent pharmacist in Millwood, New York. “There’s no reason I should be cut off from ordering these products to dispense to my legitimate patients that need it.”

It’s unclear how the thresholds are impacting major chain pharmacies. CVS Health Corp. didn’t provide comment. A spokesperson for Walgreens Boots Alliance Inc. said its pharmacists “work to resolve any specific issues when possible, in coordination with our distributors.” 

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Psychedelic drug improves symptoms of depression for six months, finds study

psychedelic drug that gives trips lasting half an hour improves the symptoms of moderate to severe depression for up to six months, early trial results suggest.

Biotechnology company Small Pharma announced the results of its phase 2a clinical trials of the effects of a pharmaceutical-grade formulation of Dimethyltryptamine (SPL026) on major depressive disorder, simply referred to as depression.

The drug is a powerful hallucinogenic found in several plants and is the psychoactive compound found in ayahuasca, a compound used in shamanic rituals in South America.

In the study, 34 patients were given the drug during a clinical session with supportive therapy.

The individual sessions lasted less than two-and-a-half hours, and included a preparation session with a therapist, a psychedelic experience after administering the drug (where the therapist was present) lasting less than 30 minutes, and a therapy session to help patients process their trip.

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On the need for metaphysics in psychedelic therapy and research

The essential proposal of this text is that psychedelic-induced metaphysical experiences should be integrated and evaluated with recourse to metaphysics. It will be argued that there is a potential extra benefit to patients in psychedelic-assisted therapy if they are provided with an optional, additional, and intelligible schema and discussion of metaphysical options at the integrative phase of the therapy. This schema (the “Metaphysics Matrix”) and a new Metaphysics Matrix Questionnaire (“MMQ”) stemming therefrom will be presented, the latter of which can also be used as an alternative or additional tool for quantitative measurement of psychedelic experience in trials. Metaphysics is not mysticism, despite some overlap; and certainly not all psychedelic experience is metaphysical or mystical—all three terms will be defined and contrasted. Thereafter psychedelic therapy will be presented and analysed in order to reveal the missing place for metaphysics. Metaphysics, with epistemology (theory of knowledge) and axiology (ethics and aesthetics), is a defining branch of Philosophy. Metaphysics, in contrast to mysticism, is considered to be based on argument rather than pure revelation. Thus, in psychedelic-assisted psychotherapy one sees here the potential bridge between reason-based philosophy and practical therapy—or, more broadly, with psychedelic-assisted psychotherapy there is the potential and mutually beneficial fusion of philosophy with practical science.

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Psychedelics and mental health: Having mystical experiences may yield strongest benefits

It’s a trope seen countless times in books and movies. A character emerges from a drug-induced psychedelic stupor with a fresh outlook and more positive perspective on life. According to new findings from The Ohio State University, however, there may really be some truth to this hallucinogenic notion. Scientists report particularly mystical and insightful psychedelic drug experiences may be associated with an enduring drop in both anxiety and depression symptoms.

Study authors performed a comprehensive machine learning analysis of data pertaining to nearly 1,000 survey respondents who answered questions about their previous non-clinical experiences with psychedelic drugs. Sure enough, those scoring the highest on questionnaires assessing the mystical and insightful nature of their experiences also consistently reported improvements in both depression and anxiety.

Of course, there’s also the risk of encountering a “bad trip.” What happens if a psychedelic experience becomes unpleasant, frightening, or destabilizing? Surprisingly, the study actually found that even challenging psychedelic trips can be beneficial — especially within the context of mystical and insightful experiences. This finding in particular may be especially helpful for practitioners to know as they guide patients through clinical trials focusing on the therapeutic potential of psychedelics.

“Sometimes the challenge arises because it’s an intensely mystical and insightful experience that can, in and of itself, be challenging,” says senior study author Alan Davis, assistant professor and director of the Center for Psychedelic Drug Research and Education in The Ohio State University College of Social Work, in a media release.

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New Jersey factory imports cocaine plant that flavors Coca-Cola thanks to DEA arrangement

Guess you really can’t beat the real thing.

Coca-Cola gets its iconic taste thanks in part to a chemical processing factory in a sleepy New Jersey neighborhood that has the country’s only license to import the plant used to make cocaine.

The Maywood-based facility, now managed by the Stepan Company, has been processing coca leaves for the soft-drink giant for more than a century and had its license to import them renewed by the Drug Enforcement Agency earlier this year.

The coca leaves are used to create a “decocainized” ingredient for the soda and the leftover byproduct is sold to the opioid manufacturing company Mallinckrodt, which uses the powder to make a numbing agent for dentists, DailyMail reported.

It is unclear how much coca leaves the Stepan Company imports annually, although the New York Times reported in 1988 that it brought in between 56 and 588 metric tons of coca leaves from Peru and Bolivia each year, citing DEA figures.

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“Grandma of the Police Officers Association” in California Arrested for Importing Fentanyl From China and Other Countries

As the drug crisis in America rages on as opioids and fentanyl pour across our unsecured border from the Mexican drug cartels supplied by Chinese “pharmaceuticals,” an unsuspecting trafficker has emerged.

San Jose Police Officers Association police union executive Joanne Marian Segovia was arrested on Wednesday for attempting to import a synthetic opioid called Valeryl fentanyl.  If convicted, she faces up to 20 years in federal prison.

Police union president Sean Pritchard told the New York Post that Segovia was like “the grandma of the POA…this is not the person we’ve known, the person who has worked with fallen officers’ families, organized fundraisers for officers’ kids…”

Segovia was allegedly importing packages of drugs from China, Canada, India and other countries and disguising them as common items such as makeup, chocolates, and food supplements.  She has received at least 61 packages at her home from 2015 through 2023.

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Gov. Hochul Proposes Heavy Fines for Illicit Cannabis Shops

Illegal cannabis sellers could see sky-high fines under new legislation proposed by Gov. Kathy Hochul on Wednesday, giving state officials greater power to crack down on New York’s illicit pot market.

The bill would set fines up to $10,000 a day for shops that sell cannabis without a license, and businesses found possessing illegal marijuana plants or products could be hit with penalties as high as $200,000, according to the proposed rules.

It would also give the Office of Cannabis Management (OCM), the state agency overseeing marijuana retail licensing, the authority to seize illegal products and allow OCM to shut down unlicensed cannabis retailers. 

“The continued existence of illegal dispensaries is unacceptable, and we need additional enforcement tools to protect New Yorkers from dangerous products and support our equity initiatives,” Hochul said in a statement.

Under the proposed law, OCM could investigate any location growing, distributing or selling cannabis that has not been sourced from a legal distributor and taxed. OCM, the attorney general or local police would be able to enforce a preliminary injunction to stop businesses suspected of selling cannabis without a license, according to the bill.

Hochul’s proposal is the latest move in a state and city effort to shutter the thousands of illegal pot shops that have cropped up in New York City, threatening its fledgling legal market. 

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