Tag: science

Biden’s NIH Refuses To Answer Questions About University Of Pittsburgh Experiments On Aborted Babies

Daines was referring to multiple physicians’ claims that Pitt’s statements “point to the possibility” that organs were “extracted from live fetuses.” That was based on statements the university made about minimizing ischemia time, which refers to “the time after the tissue collection procedure and before cooling for storage and transport.”

The university’s application to NIH also prompted lawmakers to question whether the university had violated fetal tissue trafficking laws as part of its federally funded “GUDMAP” research program. In applying for NIH funds, Pitt said it sought to “develop a pipeline to the acquisition, quality control and distribution of human genitourinary [urinary and genital organs and functions] samples obtained throughout development (6-42 weeks gestation).”

So far, the university has denied any wrongdoing and claimed it played no role in medical procedures. It’s unclear, however, why the university made comments about ischemia time and obtaining quality tissue.

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CELLULAR REJUVENATION THERAPY SAFELY REVERSES SIGNS OF AGING IN MICE

Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular disease and cancer. Now, scientists at the Salk Institute, in collaboration with Genentech, a member of the Roche group, have shown that they can safely and effectively reverse the aging process in middle-aged and elderly mice by partially resetting their cells to more youthful states.

“We are elated that we can use this approach across the life span to slow down aging in normal animals. The technique is both safe and effective in mice,” says co-corresponding author Juan Carlos Izpisua Belmonte, professor in Salk’s Gene Expression Laboratory and holder of the Roger Guillemin Chair. “In addition to tackling age-related diseases, this approach may provide the biomedical community with a new tool to restore tissue and organismal health by improving cell function and resilience in different disease situations, such as neurodegenerative diseases.”

As organisms age, it is not just their outward appearances and health that change; every cell in their bodies carries a molecular clock that records the passage of time. Cells isolated from older people or animals have different patterns of chemicals along their DNA—called epigenetic markers—compared to younger people or animals. Scientists know that adding a mixture of four reprogramming molecules—Oct4, Sox2, Klf4 and cMyc, also known as “Yamanaka factors”—to cells can reset these epigenetic marks to their original patterns. This approach is how researchers can dial back adult cells, developmentally speaking, into stem cells.

In 2016, Izpisua Belmonte’s lab reported for the first time that they could use the Yamanaka factors to counter the signs of aging and increase life span in mice with a premature aging disease. More recently, the team found that, even in young mice, the Yamanaka factors can accelerate muscle regeneration. Following these initial observations, other scientists have used the same approach to improve the function of other tissues like the heart, brain and optic nerve, which is involved in vision.

In the new study, Izpisua Belmonte and his colleagues tested variations of the cellular rejuvenation approach in healthy animals as they aged. One group of mice received regular doses of the Yamanaka factors from the time they were 15 months old until 22 months, approximately equivalent to age 50 through 70 in humans. Another group was treated from 12 through 22 months, approximately age 35 to 70 in humans. And a third group was treated for just one month at age 25 months, similar to age 80 in humans.

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Bill Gates-Linked Lab Developing Vaccine That Spreads Like a Virus To Vaccinate Anti-Vaxxers

A team of Bill-Gates linked research scientists have announced they are developing a needle-less vaccine that spreads itself like a virus, meaning people will “catch” the vaccine like they would a cold or flu, without the need for needles and injections.

The research is being subsidised by high-profile funding organisations, including the U.S. National Institutes of Health (NIH), which has longstanding financial ties to the Bill & Melinda Gates Foundation.

An international team of researchers are working on an experimental self-spreading vaccine that could stop the virus leaping from rats to humans — a phenomenon scientists call zoonotic spillover.

The drive to develope self-spreading vaccines is not without controversy. The DHSC paper notes: ‘Self-spreading vaccines are less lethal but not non-lethal: they can still kill.

‘Some people will die who would otherwise have lived, though fewer people die overall.

‘The other issue is there is no consent (for vaccination) from the majority of patients.’

But some ethics experts say there are parallels for ‘treating’ mass populations for public health issues without first getting individual consent.

For example, the fluoridation of mains drinking water to prevent tooth decay already happens in some parts of the UK and the Government is considering extending it to all of England.

‘Nobody is asked whether they give consent, even those who disagree with it,’ says Professor Dominic Wilkinson, a medical ethics specialist at Oxford University. ‘Instead, we entrust elected officials to examine the likely health benefits and make decisions based on the evidence.

‘I don’t think that there is anything intrinsically different when it comes to the idea of self-spreading vaccines.’

However, some scientists have serious misgivings about the risk that weakened viruses could mutate into a more potent form once they are free to spread in the population.

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Quantum leap: Has next-gen computing moved from hype to hope?

Australian scientists believe they have taken a key step towards building a silicon quantum computer – a device that could take quantum computing from hype to mainstream.

Silicon quantum computers marry quantum technology with the same element – silicon – used in existing computer chips, so can hopefully be easily mass-produced. Australia leads the world in the technology, which competes with at least eight other types of quantum computer.

But despite a decade of hype and billions of dollars in investment, quantum computing in general remains a long way off fulfilling its full promise, experts admit. At this stage, there are few uses for such a computer and scientists remain a long way from building a device that could calculate serious equations.

The Australian-led study, published on the front cover of leading journal Nature in January, shows silicon quantum computers can now be operated with better than 99 per cent accuracy.

“This has long been understood as the next big step you needed to take,” says Professor Andrea Morello of the University of NSW, who led the work.

Being 99 per cent-plus accurate seems a small achievement for a computer, but it’s a big deal in quantum because it is considered the threshold at which you could scale quantum processors into an actual computer, he says.

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U.S. Govt Spent Over $2.3 Million Injecting Puppies With Cocaine.

The National Institutes of Health spent over $2.3 million on studies that injected puppies with cocaine.

The experiment, revealed through a Freedom of Information Act (FOIA) request filed by the White Coat Waste Project, follows previously unearthed studies funded by National Institute of Allergy and Infectious Disease Director Anthony Fauci that “debarked” beagle puppies.

Seven six-month-old Beagle puppies were forced to wear a drug-injecting jacket that allowed them to be dosed with cocaine again and again and again for months, along with an ‘experimental compound,’ to see how the two drugs interacted.

The year-long experiment, which began in September 2020, was filmed so research could evaluate the puppies’ adverse reactions” to the drugs. Prior to the drugs being administered, the puppies were forced to undergo surgery, where they were implanted with a “telemetry unit” to monitor their vital signs throughout the experiment.

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Researchers regrow frog’s lost leg

For millions of patients who have lost limbs for reasons ranging from diabetes to trauma, the possibility of regaining function through natural regeneration remains out of reach. Regrowth of legs and arms remains the province of salamanders and superheroes.

But in a study published in the journal Science Advances, scientists at Tufts University and Harvard University’s Wyss Institute have brought us a step closer to the goal of regenerative medicine.

On adult frogs, which are naturally unable to regenerate limbs, the researchers were able to trigger regrowth of a lost leg using a five-drug cocktail applied in a silicone wearable bioreactor dome that seals in the elixir over the stump for just 24 hours. That brief treatment sets in motion an 18-month period of regrowth that restores a functional leg.

Many creatures have the capability of full regeneration of at least some limbs, including salamanders, starfish, crabs, and lizards. Flatworms can even be cut up into pieces, with each piece reconstructing an entire organism. Humans are capable of closing wounds with new tissue growth, and our livers have a remarkable, almost flatworm-like capability of regenerating to full size after a 50% loss.

But loss of a large and structurally complex limb—an arm or leg—cannot be restored by any natural process of regeneration in humans or mammals. In fact, we tend to cover major injuries with an amorphous mass of scar tissue, protecting it from further blood loss and infection and preventing further growth.

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