Tag: science

Epstein files reveal deeper ties to scientists than previously known

Newly released files from the investigation of convicted sex offender Jeffrey Epstein reveal that his ties to the scientific community were deeper than previously known.

Epstein, who died by suicide in 2019 after being arrested and charged with sex trafficking, was a wealthy financier who invested millions in science projects and socialized with researchers. It was already known that, after Epstein’s initial conviction for sex crimes in 2008, some scientists continued to associate with and take money from him, prompting fallout at top research institutions. For instance, Epstein gave US$800,000 to the Massachusetts Institute of Technology in Cambridge, which led two scientists to resign and the university to suspend another.

But last Friday’s release of more than three million files linked to Epstein — including e-mails, photographs and financial documents — has unveiled even more scientists in his orbit. Mentions of the researchers do not indicate wrongdoing or involvement in Epstein’s criminal activity, but they do shed light on how deeply he was involved in some of the science he funded. This is the largest batch of files made public by the US Department of Justice since Congress passed the Epstein Transparency Act late last year, mandating that the federal government release all documents pertaining to the financier.

Science stars

The files include new information about interactions between Epstein and scientists whose links to him were already known. For example, the documents contain correspondence from theoretical physicist Lawrence Krauss, whose science-outreach organization received $250,000 from Epstein. “I thought we agreed no comment !!!!!,” Epstein wrote in 2018, as Krauss responded to media inquiries about an investigation of sexual misconduct that led to Krauss’s ousting from Arizona State University in Tempe.

Krauss explained his interaction with Epstein in an e-mail to Nature: “I sought out advice from essentially everyone I knew when false allegations about me were circulated.” He added that he had no knowledge of the “horrendous crimes” — the sex trafficking — that Epstein was later accused of. “I was as shocked as the rest of the world when he was arrested.”

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Did Scientists Just Achieve “Inception”? Experiments Show “Dream Engineering” May Be a Reality

Northwestern University scientists exploring the possibility of programming your brain to solve problems during rapid eye movement (REM) sleep have found compelling evidence that this type of “dream engineering” is not only possible, but potentially valuable as well.

The team behind the sci-fi-sounding research suggests that the ability to engineer dreams for problem-solving could motivate other researchers to “take dreams more seriously” as a tool for improved mental health and well-being.

They also suggest that their findings offer a crucial step toward proving the theory that REM sleep “may be especially conducive to helping individuals come up with creative solutions to a problem.”

Dream Engineering with Music During REM Sleep

Although there is anecdotal evidence that people may have greater success at solving a problem after they “sleep on it,” in the past, there has been little scientific support for the role of sleep in such Eureka moments. Studying the role our dreams might play in problem-solving has also proven elusive because it is difficult to systematically manipulate what a sleeper is dreaming about.

To investigate the possibility of a higher level of “dream engineering,” the researchers examined what is known as targeted memory reactivation (TMR), where subjects are presented with sounds during sleep that remind them of a prior experience of trying to solve a specific puzzle. The research team then recruited 20 individuals who reported previous experience with lucid dreaming, a state where the dreamer has some level of conscious awareness in their dream.

During the first phase of the experiments, the subjects were presented with complex brain-teaser puzzles and given a 3-minute time limit to solve them. Significantly, each puzzle was accompanied by its own musical soundtrack. The team notes that difficult puzzles, combined with the short test duration, left most volunteers unable to find the solution.

Next, the researchers set up polysomnographic recordings to measure and document the subjects’ physiology while they slept overnight in the lab. Notably, they used electrophysical verification to confirm each subject was asleep before progressing to the next phase.

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America’s Vaunted “Experts”: Often Wrong but Never in Doubt?

In our time we’ve traded wise men for experts — Confucius for the credentialed, Aquinas for academicians, Democritus for the degreed. Consequently, we don’t make our ancestors’ bush-league mistakes, such as the Romans using lead pipes, drilling holes in people’s heads to treat mental derangement, or selling radium-laced candy and water.

We make different bush-league mistakes. In fact, says Rob Long, pondering all the recent decades’ blunders, “you might start to wonder if anyone knows anything.”

“Here’s what I mean,” explains Long, a television writer and producer opining at the Washington Examiner:

COVID masks, mortgage-backed securities, weapons of mass destruction in Iraq, carbs, red wine, voter turnout, lard, phonics, and Pluto. (Among others.) Smart people — and I knew some of the folks who were involved in the home finance catastrophe of 2007, and let me assure you that they were smart — seem to be making a lot of costly and dangerous mistakes. It often seems like we’re living through an Age of Blunder.

Here’s a noncontroversial example from history: say what you like about the brutal Stalinist regime of the (thankfully late) German Democratic Republic, but they were pretty good about spying on their own citizens. … They knew everything there was to know about the German Democratic Republic except that it was about to collapse. Which was the one thing they really needed to know. Talk about the Age of Blunder!

How Expert Are They?

After providing a few more examples, Long discussed the recent blizzard that struck New York and elsewhere. He said that he and some friends were discussing beforehand whether it would materialize. “Experts,” ya know? But they were right on this occasion, he stated.

Short-term weather, however, can be predicted with decent accuracy. But on a related note, there’s the following.

A generation ago, in 2000, climate scientist Dr. David Viner stated that within just a handful of years, snowfall will be “a very rare and exciting event. Children just aren’t going to know what snow is.”

Now, Viner was talking about Great Britain — which was hit by a “devastating snowstorm” just last year. But then there’s the reality here in the Colonies. Only a week ago, parts of my southern N.Y. county got buried under 17 inches of global warming.

Oh, and if you think nothing could be finer than poking fun at Viner, know that he’s hardly alone. The late Professor Walter E. Williams illustrated this beautifully in his 2017 piece “Environmentalists’ Wild Predictions.”

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Scientists Have Developed a Laser-Controlled Magnet With No Heating Required

Swiss researchers have developed a new technique that enables magnetic polarity changes using only a laser beam, an advancement with major potential for creating adaptable electronic circuits.

Using a special ferromagnet, researchers at the University of Basel and ETH Zurich were able to manipulate magnetic polarity using laser light, without any additional heating. The results were reported in a recent paper published in Nature, showcasing a major advancement that can produce different magnetic polarities at separate points within a single piece of material.

Ferromagnets Explained

Ferromagnets are the most common types of magnets used in our everyday world. They operate on the synchronized spin of electrons, all rotating in the same direction. That unanimous spin direction generates their magnetic power, allowing magnets to stick to metal and compasses to point toward the Earth’s magnetic poles.

However, this is only true below a certain temperature threshold. Inside magnets is also a chaotic thermal motion that remains ever-present. When the magnets are relatively cool, this motion is weak, allowing the electron interactions to overcome it and generate the synchronized spin. By contrast, above a certain temperature, the thermal motion becomes so powerful that it overrides the electrons’ synchronization, introducing larger-scale chaos that causes the material to lose its ferromagnetism.

That threshold is typically used to intentionally alter the polarity of a ferromagnetic material. Once the heated magnet begins to cool, its electrons again order themselves into a synchronized spin, typically in a different direction.

The new research by researchers at the University of Basel and ETH Zurich changes all of this, altering the polarity without applying any heat.

Constructing a Laser Switchable Magnet

“What’s exciting about our work is that we combine the three big topics in modern condensed matter physics in a single experiment: strong interactions between the electrons, topology and dynamical control,” said co-author Prof. Dr. Ataç Imamoğlu of ETH in Zurich.

The researchers built their laser switchable magnet from two thin, but slightly twisted layers of the organic semiconductor molybdenum ditelluride. Their two-layer material allowed topological states to form—that is, quantum states that are permanently defined and cannot be altered by small local disturbances.

Experiments revealed that the material’s electrons existed in tunable topological states that could be manipulated from insulating to conducting. More intriguingly, both states feature parallel aligned electron spins, turning the material into a ferromagnet.

“Our main result is that we can use a laser pulse to change the collective orientation of the spins,” says Olivier Huber, a PhD candidate at ETH.

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Scientists mimicking the Big Bang accidentally turn lead into gold

Medieval alchemists dreamed of transmuting lead into gold.

Today, we know that lead and gold are different elements, and no amount of chemistry can turn one into the other.

But our modern knowledge tells us the basic difference between an atom of lead and an atom of gold: the lead atom contains exactly three more protons. So can we create a gold atom by simply pulling three protons out of a lead atom?

As it turns out, we can. But it’s not easy.

While smashing lead atoms into each other at extremely high speeds in an effort to mimic the state of the universe just after the Big Bang, physicists working on the ALICE experiment at the Large Hadron Collider in Switzerland incidentally produced small amounts of gold.

Extremely small amounts, in fact: a total of some 29 trillionths of a gram.

How to steal a proton

Protons are found in the nucleus of an atom. How can they be pulled out?

Well, protons have an electric charge, which means an electric field can pull or push them around. Placing an atomic nucleus in an electric field could do it.

However, nuclei are held together by a very strong force with a very short range, imaginatively known as the strong nuclear force. This means an extremely powerful electric field is required to pull out protons – about a million times stronger than the electric fields that create lightning bolts in the atmosphere.

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Bay Area scientist launches new company with sights on gene-edited babies

Last month, as he announced the launch, he said that Preventive has raised almost $30 million from private funding.

The funding is reportedly coming from some heavy hitters in the tech world, including OpenAI CEO Sam Altman and his husband Oliver Mulherin.

Harrington also said his team included leading experts in the fields of reproductive technology, reproductive medicine and genome-editing.

“Our goal is straightforward,” he wrote, “to determine through rigorous preclinical work whether preventive gene editing can be developed safely to spare families from severe disease.”

Harrington acknowledged the major ethical concerns around the science and the gray areas in the regulatory process, which he said, have opened the field to potentially detrimental outcomes. 

“The combination of limited expert involvement and lack of a clear regulatory pathway has created conditions for fringe groups to take dangerous shortcuts that could harm patients and stifle responsible investigation,” the researchers said, adding, “Given that this technology has the potential to save millions of lives, we do not want this to happen.”

Gene editing can only be used in in vitro fertilization to allow for the first step of genetic testing on an embryo.

“It requires IVF because you have to have the embryo in a dish,” explained Stanford law professor Henry (Hank) Greely, a leading expert on ethical, legal, and social implications in bioscience technologies.

Once a test determines an embryo has the DNA makeup of a genetic disease, for example, like Huntington’s or cystic fibrosis, scientists would then use the DNA editing technique known as Clustered Regularly Interspaced Short Palindromic Repeats, or CRISPR, to make alterations to the DNA.

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Ancient Cannabis Enzymes Reveal How THC and CBD First Evolved

Scientists are taking a deeper look at the origins of cannabis chemistry by reconstructing enzymes from ancient plants, offering new insight into how cannabis first developed the ability to produce compounds like THC and CBD.

In a recent study published in Plant Biotechnology Journal, researchers at Wageningen University & Research rebuilt molecular structures that existed millions of years ago, revealing that ancient forms of cannabis enzymes were more flexible and robust than those found in modern plants.

The team behind the research says they have successfully traced the evolution of cannabinoid chemistry and identified molecular tools that could improve the biotechnological production of modern medicinal cannabinoids.

The Origin of Cannabinoids

In modern cannabis plants, specialized enzymes are responsible for making individual cannabinoids like THC or CBD. Each enzyme is highly efficient at producing one specific compound. The new study shows that this precision is a recent development in cannabis evolution, rather than something that existed from the start.

Early ancestors of cannabis used versatile enzymes that could create several cannabinoids at once. These enzymes became more specialized over time as gene duplication occurred. This led to the distinct chemical profiles seen in cannabis plants today.

The research team provided direct evidence for this evolutionary process by reconstructing ancient cannabis enzymes in the lab. Their results show that the pathways for creating specific cannabinoids like THC appeared relatively recently and became more specialized over time through natural selection.

Rebuilding Lost Enzymes

The team relied on ancestral sequence reconstruction to study this evolutionary history. They compared DNA from modern cannabis and related species to determine what cannabinoid-producing enzymes looked like millions of years ago.

The researchers synthesized the predicted enzymes and tested their functions in the lab. Many of the reconstructed enzymes converted precursor molecules into several different cannabinoids, unlike the more specialized modern enzymes.

These experiments enabled the team to directly test evolutionary hypotheses that had previously relied solely on genetic comparisons.

Ancient Enzymes as Biotech Tools

The most immediate implications of the study are for biotechnology rather than evolutionary biology. When the researchers expressed ancient enzymes in microbial systems, they found that the reconstructed enzymes were often easier to use than those found in modern cannabis plants.

“What once seemed evolutionarily ‘unfinished’ turns out to be highly useful,” said Robin van Velzen, who led the study with colleague Cloé Villard. “These ancestral enzymes are more robust and flexible than their descendants, which makes them very attractive starting points for new applications in biotechnology and pharmaceutical research.”

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New insight into light-matter thermalization could advance neutral-atom quantum computing

Light and matter can remain at separate temperatures even while interacting with each other for long periods, according to new research that could help scale up an emerging quantum computing approach in which photons and atoms play a central role.

In a theoretical study published in Physical Review Letters, a University at Buffalo-led team reports that interacting photons and atoms don’t always rapidly reach thermal equilibrium as expected.

Thermal equilibrium is the process by which interacting particles exchange energy before settling at the same temperature, and it typically happens quickly when trapped light repeatedly interacts with matter. Under the right circumstances, however, physicists found that photons and atoms can instead settle at different—and in some cases opposite—temperatures for extended periods.

Implications for quantum computing

These so-called prethermal states are fleeting on human timescales, but they can last long enough to matter for neutral-atom quantum computers, which rely on interactions between photons and atoms to store and process information.

“Thermal equilibrium alters quantum properties, effectively erasing the very information those properties represent in a quantum computer,” says the study’s lead author, Jamir Marino, Ph.D., assistant professor of physics in the UB College of Arts and Sciences. “So delaying thermal equilibrium between photons and atoms—even for a matter of milliseconds—offers a temporal window to preserve and process useful quantum behavior.”

All quantum computers store and process information using qubits—the most basic units of quantum information and analogous to the binary bits used in classical computers. While classical bits can exist either as a 1 or a 0, qubits have the ability to exist in a superposition of two states at once, allowing for infinitely more complex calculations.

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Superconductivity Breakthrough Brings Practical Use Closer than Ever, as Team Unveils “Hidden Magnetic Order in the Pseudogap”

In the quest for room-temperature superconductivity, an international team of physicists has uncovered a link between magnetism and the mysterious phase of matter known as the pseudogap, which may finally yield clues to achieving superconductivity above frigid, artificial temperatures.

Given the artificially cold temperatures on which current superconducting technologies rely, making their use impractical for many applications, the search for new room-temperature superconducting materials is a major goal of applied physics research.

Now, physicists from the Max Planck Institute of Quantum Optics in Germany and the Center for Computational Quantum Physics (CCQ) at the Simons Foundation’s Flatiron Institute in New York City are potentially helping to advance scientists closer than ever to superconducting at practical temperatures, as reported in a recent paper published in the Proceedings of the National Academy of Sciences.

Superconductors

Superconductors are materials that allow electrical current to flow without resistance. However, even in superconducting materials, the property only becomes active below a threshold temperature. This limits technological applications, as the materials require bulky cooling apparatus to maintain the desired temperatures, which are well below typical room temperatures.

Despite the volume of research involving superconductivity, in many ways it remains poorly understood, awaiting insights that will enable the next generation of quantum computing and other applications.

Some superconductors operate at what are considered “high temperatures,” although, in practical terms, these are still well below typical room temperatures and usually only slightly above absolute zero. What is interesting about those materials, however, is that they tend to exhibit a “pseudogap state” in which electrons begin to behave strangely as they transition to a superconducting state.

Understanding how this state leads to superconductivity could be essential to revealing the mechanisms at play and then applying them to produce room-temperature superconductors.

Testing the Pseudogap

Advancing toward resolving this long-standing issue, researchers used a quantum simulator set slightly above absolute zero to monitor electron spins. They identified that the up or down spins of electrons were influenced by their neighbors in a universal pattern.

At the center of the team’s work was the Fermi-Hubbard model, which describes electron interactions in a solid. The research team’s simulations successfully recreated this model, rather than a real-world material, using lithium atoms in an optical lattice of laser light at temperatures on the order of billionths of a degree above absolute zero. Simulations allowed the researchers a level of precision control impossible in real-world experiments.

When materials host an unaltered amount of electrons, they spin in an alternating pattern called antiferromagnetism. Through a process called “doping,” electrons can be removed, disrupting the magnetic order in a way that physicists had long assumed was permanent. Yet in the new observations, the team discovered a hidden layer of organization present beneath the seeming chaos at very low temperatures.

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Physicists Have Achieved Quantum “Alchemy” by Exciting Electrons to High-Energy States

A promising—and powerful—new engineering breakthrough could soon enable researchers to alter the properties of materials by exciting electrons to higher-than-normal energy levels.

In physics, Floquet engineering involves changes in the properties of a quantum material induced by a driving force, such as high-powered light. The resulting effect causes the material’s behavior to change, introducing novel quantum states with properties that do not occur under normal conditions.

Given its promising applications, Floquet engineering has remained of interest to researchers for many years. Now, a team of scientists from the Okinawa Institute of Science and Technology (OIST) and Stanford University says they have developed a new method for achieving Floquet physics that is more efficient than past methods that rely on light.

21st Century Alchemy?

Professor Keshav Dani, a researcher with OIST’s Femtosecond Spectroscopy Unit, said in a statement announcing the breakthrough that the team’s new approach leverages what are known as excitons, which have proven far more powerful in coupling with quantum materials than existing methods “due to the strong Coulomb interaction, particularly in 2D materials.”

Because of this, Dani says, excitons “can thus achieve strong Floquet effects while avoiding the challenges posed by light.” The team says this offers a novel means of exploring various applications, which include “exotic future quantum devices and materials that Floquet engineering promises.”

Such unique phenomena could enable material science applications that are almost akin to alchemy, in that the concept of creating new materials simply by shining light on them sounds more like science fiction than even the most advanced 21st-century engineering.

Floquet Engineering

In the past, Floquet effects have remained elusive in the lab, although investigations over the years have demonstrated their promise, provided they can be achieved under practical conditions. However, a major limiting factor has been reliance on intense light as the primary driving force, which can also lead to damage or even vaporization of the materials, thereby limiting useful results.

Normally, Floquet engineering focuses on achieving such effects under quantum conditions that challenge our usual expectations of time and space. When researchers employ semiconductors or similar crystalline materials as a medium, electrons behave in accordance with what one of these dimensions—space—will allow. This is because of the distribution of atoms, which confines electron movement and thereby limits their energy levels.

Such conditions represent just one “periodic” condition that electrons are subjected to. However, if a powerful light is shone on the crystal at a certain frequency, it represents an additional periodic drive, albeit now in the dimension of time. The resulting rhythmic interaction between light (i.e., photons) and electrons leads to additional changes in their energy.

By controlling the frequency and intensity of the light used as this secondary periodic force, electrons can be made to exhibit unique behaviors, which also cause changes in the material they inhabit for the time during which they remain excited.

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