Tag: safety

‘Wide Body of Science’ Links Endocrine-disrupting Chemicals to Infertility in Women

In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to the female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals, or EDCs.

The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.

Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note.

They continue:

“Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes … emerging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.”

In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency, or POI, and endocrine axis dysregulation.

The studies included investigating the “mechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity of endometrium, endometriosis, fetal development abnormalities, and epigenetics modulation,” the authors state.

Results from these studies show exposure to EDCs can lead to infertility and reproductive effects through various mechanisms. Altering the balance of any endocrines that impact reproduction can change fertilization outcomes.

The researchers say, “One of the most described mechanisms is when EDCs mimic hormones such as estrogen and bind to their receptors leading to hormonal disruption.” This can alter the ovulation process.

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Pesticide banned in Europe, widely used in US, speeds up brain aging

Atrazine, a widely used herbicide banned in the European Union since 2004, has been found to accelerate brain cell aging and harm the hypothalamus, according to a new study in mice. Despite being prohibited in Europe due to groundwater contamination concerns, atrazine remains the second-most-used weedkiller globally, with over 70 million pounds applied annually in the US.

The study, published last month in Research, demonstrated significant neurotoxic effects. Researchers observed a decrease in nerve cell numbers and structural damage to neurons in the hypothalamus—a brain region critical for stress response, metabolism, and hormone regulation.

The study revealed that atrazine in mice:

  • Damages nerve cells (neurons) and activates microglia, immune cells in the brain that act as its “first responders” to injury, infection, or disease.
  • Sends certain brain stem cells (hypothalamic neural stem cells, or HtNSCs) to the areas of injury in the hypothalamus.
  • Overly activates the body’s stress response system (integrated stress response pathway), making these HtNSCs age prematurely (stop dividing and growing) and impairing their ability to maintain and repair the hypothalamus by multiplying and turning into other types of nerve cells.

These findings highlight how atrazine prematurely ages hypothalamic stem cells, impairing their ability to repair damage and raising concerns about links to neurodegenerative diseases like Alzheimer’s and Parkinson’s. Growing evidence suggests that persistent exposure to pesticides such as atrazine may contribute to the prevalence of these age-related conditions.

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U.S. Allows This Food Additive in Breads, Cakes and Ice Cream — But It’s Banned in Europe

Titanium dioxide is the most widely used whitening pigment in the world and has been linked to adverse health effects, particularly genotoxicity and intestinal inflammation.

It is applied as a food coloring and a whitening agent to a wide variety of foods, including chewing gum, cakes, candies, breads and ice cream.

Because of health risks, France banned titanium dioxide, or TiO2, as a food additive in 2020. Two years later the European Union (EU) also banned titanium dioxide as a food additive.

But in the U.S., titanium dioxide is found all over the grocery shelves.

Candy like Skittles, Starbursts and Jell-O, gum like Trident White peppermint gum and Mentos Freshmint Gum, cake products like Duncan Hines Creamy Vanilla Frosting and Nabisco Chips Ahoy! cookies are just a few of the myriad food items that contain the additive.

A significant body of research, mostly from rodent models and in vitro studies, has linked titanium dioxide with health risks related to the gut, including intestinal inflammation, alterations to the gut microbiota and more.

It is classified by the International Agency for Research on Cancer in Group 2B, as possibly carcinogenic to humans.

As a food additive, titanium dioxide and its nanoparticles in particular have been associated with DNA damage and cell mutations, which in turn, have the potential to cause cancer. When used as a food coloring, it is known as E171.

With the rise of nanotechnology, research in recent years has also shown the dangers of titanium dioxide or TiO2 nanoparticles, and their genotoxicity, which refers to a chemical agent’s ability to harm or damage DNA in cells, thus potentially causing cancer.

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Unmasking the Contamination Crisis in mRNA Injectable Drugs: A Public Health Catastrophe in the Making

The alarm bells began to ring loudly when Kevin McKernan first uncovered alarmingly high levels of DNA contamination in early 2023, a finding that has since been corroborated by numerous independent scientists. The most recent revelation comes from a study conducted in a laboratory utilized by the FDA itself, exposing staggering levels of contamination in every analyzed vaccine lot. This discovery, particularly significant because of the FDA’s connection, suggests that the problem may be even worse than initially reported. Methodological limitations raise the possibility that larger, more dangerous DNA fragments capable of disrupting cellular functions remain undetected. Instead of taking responsibility, the FDA—the agency charged with safeguarding public health—has chosen to distance itself from these damning findings. By denying ownership of the study and refusing to act, the FDA has demonstrated a chilling disregard for public safety, prioritizing perception over accountability.

DNA contamination, even in small fragments, is far from a hypothetical risk confined to theoretical science. These fragments can trigger immune pathways like cGAS-STING,[1] leading to chronic inflammation and immune system dysregulation. The threat of genomic integration—where foreign DNA integrates into human cells—looms ominously, with potentially catastrophic consequences if it occurs in critical regions such as oncogenes or tumor suppressor genes. This risk is compounded by the lipid nanoparticles (LNPs) used in vaccine delivery, which protect these fragments and enhance their ability to enter human cells. The very mechanism designed to deliver the mRNA payload efficiently may inadvertently pave the way for these fragments to wreak havoc within the human body.

The FDA laboratory’s report indicated that the DNA contamination consisted of non-replicating fragments, which might appear less dangerous at first glance. The probability of genomic integration was estimated at approximately 1 in 10 million cells. While this figure may sound reassuringly small, the broader context reveals a much more alarming reality. The human body contains roughly 37 trillion cells, meaning that even such a low probability translates to an average of around 3,700 cells per individual potentially experiencing genomic integration. If foreign DNA integrates into critical genomic regions in just one of these cells,[2] the results could be catastrophic, leading to mutations that may escape immune detection and cause severe health outcomes over time.

When scaled to the billions of vaccinated individuals worldwide, the potential for population-wide health impacts becomes staggering. The sheer number of affected cells across global populations magnifies the risk of rare but severe reactions, challenging the dismissive assurances of safety provided by regulatory bodies. These are not merely theoretical risks; they are statistically plausible outcomes that demand immediate scrutiny and decisive action. The scale and scope of these potential outcomes should compel regulatory agencies and manufacturers to halt vaccine distribution until these dangers are fully understood and mitigated.

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Federal toxicology agency under CDC now says fluoride lowers IQ, in comprehensive meta analysis of 74 studies

The addition of Fluoride to drinking water is one of public health’s most durable achievements. Over 200 million Americans use water from public water supplies to which fluoride has been added. And most use toothpaste to which fluoride was added. One friend was instructed to swallow the fluoride toothpaste after brushing, which he did for many years. Please don’t.

This is what a historical NIH website has to say about the history of fluoridation, patting itself on the back:

In 1945, Grand Rapids became the first city in the world to fluoridate its drinking water. The Grand Rapids water fluoridation study was originally sponsored by the U.S. Surgeon General, but was taken over by the NIDR (NIH’s National Institute of Dental Research) shortly after the Institute’s inception in 1948. During the 15-year project, researchers monitored the rate of tooth decay among Grand Rapids’ almost 30,000 schoolchildren. After just 11 years, Dean- who was now director of the NIDR-announced an amazing finding. The caries rate among Grand Rapids children born after fluoride was added to the water supply dropped more than 60 percent. This finding, considering the thousands of participants in the study, amounted to a giant scientific breakthrough that promised to revolutionize dental care, making tooth decay for the first time in history a preventable disease for most people.

A Lasting Achievement

Almost 30 years after the conclusion of the Grand Rapids fluoridation study, fluoride continues to be dental science’s main weapon in the battle against tooth decay. Today, just about every toothpaste on the market contains fluoride as its active ingredient; water fluoridation projects currently benefit over 200 million Americans, and 13 million schoolchildren now participate in school-based fluoride mouth rinse programs. As the figures indicate, McKay, Dean, and the others helped to transform dentistry into a prevention-oriented profession. Their drive, in the face of overwhelming adversity, is no less than a remarkable feat of science-an achievement ranking with the other great preventive health measures of our century.

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More Big Pharma/Big Government Attacks Coming – Arepanrix: Package Insert & Approval Letter

By now, readers know this writer is a staunch advocate for proper informed consent following the informed consent process. Previously, the injectable vaccine AUDENZ for H5N1 manufactured by Seqirus was reviewed to inform the public about the product. While it was a long read, the package insert for AUDENZ proved there were not enough participants to represent the population, placebo-controlled trials were only conducted in one study, and the one-year follow-up was not long enough to uncover potential serious adverse events relating to development of autoimmune diseases. Understandably, reading package inserts is not particularly “attention-grabbing” and can be quite boring and tedious. However, it is the only way you will receive all the information you need to give proper informed consent, which includes denying taking a product. Because of the volume of data to be covered in the AREPANRIS package insert, it will be covered in two parts.

In this article, the approval letter and package insert for AREPANRIX will be reviewed. The only approval letter for AREPANRIX on the Food and Drug Administration (FDA) website is dated October 18, 2024. This letter references another letter dated April 19, 2024, which requested a supplement to their license regarding packaging to include the proprietary name of AREPANRIX. There should be another letter indicating the initial FDA approval for this vaccine. Without the initial approval letter, there is no additional information to be gleaned besides the package insert.

AREPANRIX, manufactured by GlaxoSmithKline (GSK), is approved for active immunization for the prevention of disease caused by the Influenza A virus H5N1 subtype contained the vaccine for individuals 6 months and older. AREPANRIX comes in two vials that must be mixed before administration: one contains the H5N1 antigen and the other contains the AS03 adjuvant. The AS03 adjuvant will be explained in Part II. For individuals ages 6 months through 17 years, two doses of 0.25 ml are injected intramuscularly 21 days apart. For individuals ages 18 years and older, two doses of 0.5 ml are injected intramuscularly 21 days apart. (Sections 1 through 2.2)

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The Glaring Hypocrisy and Embedded Deceptions of the Global Food Giants

Bryce Martinez (18) from Pennsylvania is mounting a legal challenge against major food companies, alleging that their ultra-processed foods (UPFs) led to his development of Type 2 diabetes and fatty liver disease at the age of 16.

The 11 firms listed in the lawsuit are Kraft Heinz, Mondelez, Coca-Cola, Post Holdings, PepsiCo, General Mills, Nestle’s (US), WK Kellogg, Mars, Kellanova and Conagra.

UPFs have undergone multiple processing steps and often contain additives, preservatives and artificial ingredients. These UPFs have become staples in many households. Examples of UPFs are prepackaged soups, many breakfast cereals, sauces, frozen pizza, ready-to-eat meals, hot dogs, sausages, sodas, ice cream and store-bought cookies, cakes, candies and doughnuts.

Martinez’s legal team contends that the big food corporations have deliberately engineered their products to trigger addictive responses. His lawyers at Morgan & Morgan, a major US law firm, says the case is unprecedented and includes claims for conspiracy, negligence, fraudulent misrepresentation and unfair business practices.

Martinez had regularly consumed popular UPFs throughout his childhood. The lawsuit challenges the food industry’s argument that consumers have free choice in their dietary decisions. It argues that the notion of free choice is compromised by aggressive marketing tactics, especially aimed at children, and the addictive nature of these products.

UPFs are highly profitable for corporations. The same companies that dominate the UPF market are intertwined with investment firms like BlackRock and Vanguard, which also hold stakes in the pharmaceutical industry. This dual investment creates a cycle where investment firms profit from both the sale of harmful foods and the treatment of diseases associated with these products.

Furthermore, the prevailing economic system creates a paradoxical situation where workers, whose pension funds are often managed by these same investment giants, find themselves financially tethered to a cycle that undermines their own health and well-being.

There is a famous quote often attributed to farmer, poet and campaigner Wendell Berry:

People are fed by the food industry, which pays no attention to health, and are treated by the health industry, which pays no attention to food.”

For a long time, that has served both industry’s interests very well.

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Bill Gates Funds Genetically Engineered Tomatoes with Insecticides Inside Them That Attack Reproduction—And Yes, You’d Eat Them

Bill Gates is funding research to genetically engineer tomatoes to produce insecticides inside their tissues, specifically targeting the reproduction of whiteflies, a destructive agricultural pest. According to a study published last month in BMC Plant Biology, these genetically engineered (GE) tomatoes express proteins designed to infiltrate and disrupt whitefly eggs.

“The molecular tools for achieving both apoplastic and phloem-specific expression of insecticidal proteins are well developed,” the study explains, highlighting the advanced genetic strategies employed.

If commercialized, these “[t]ransgenic plants”—genetically engineered to include genes from other species—could introduce reproductive-disrupting insecticidal compounds into the human food chain.

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Microplastics Linked to Cancer and Harm to Human Reproductive, Digestive, and Respiratory Systems

Last week, the study titled Effects of Microplastic Exposure on Human Digestive, Reproductive, and Respiratory Health: A Rapid Systematic Review by Chartres et al was published in the journal Environmental Science and Technology:

Microplastics are ubiquitous environmental contaminants for which there are documented human exposures, but there is a paucity of research evaluating their impacts on human health. We conducted a rapid systematic review using the “Navigation Guide” systematic review method.

We searched four databases in July 2022 and April 2024 with no restriction on the date. We included studies using predefined eligibility criteria that quantitatively examined the association of microplastic exposure with any health outcomes. We amended the eligibility criteria after screening studies and prioritized digestive, reproductive, and respiratory outcomes for further evaluation.

We included three human observational studies examining reproductive (n= 2) and respiratory (n = 1) outcomes and 28 animal studies examining reproductive (n = 11), respiratory (n = 7), and digestive (n = 10) outcomes. For reproductive outcomes (sperm quality) and digestive outcomes (immunosuppresion) we rated overall body evidence as “high” quality and concluded microplastic exposure is “suspected” to adversely impact them. For reproductive outcomes (female follicles and reproductive hormones), digestive outcomes (gross or microanatomic colon/small intestine effects, alters cell proliferation and cell death, and chronic inflammation), and respiratory outcomes (pulmonary function, lung injury, chronic inflammation, and oxidative stress) we rated the overall body of evidence as “moderate” quality and concluded microplastic exposure is “suspected” to adversely impact them. We concluded that exposure to microplastics is “unclassifiable” for birth outcomes and gestational age in humans on the basis of the “low” and “very low” quality of the evidence.

We concluded that microplastics are “suspected” to harm human reproductive, digestive, and respiratory health, with a suggested link to colon and lung cancer. Future research on microplastics should investigate additional health outcomes impacted by microplastic exposure and identify strategies to reduce exposure.

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Key senator says U.S. vaccine safety system failing, urges reforms to testing and liability

Sen. Ron Johnson, R-Wis., who next month will begin overseeing the Senate’s most powerful investigative body, says the government’s vaccine safety system is no longer protecting Americans adequately because of conflicts of interest and lack of transparency, and he is vowing to work with the incoming Trump administration to press for sweeping reforms.

Those reforms could range from changing the vaccine liability protections of drug makers to taxpayer funding and other changes to insure the independence of safety testing, he told Just the News.

“The best solution for this is actually make these products safer, and do real science to determine whether there are certain conditions that make you more vulnerable,” Johnson said in a wide-ranging interview on the Just the News, No Noise television show.

Asked whether the current safety system led by the Food and Drug Administration and Centers for Disease Control and Prevention was adequately protecting Americans, Johnson answered: “I would say absolutely not.”

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