Tag: cannabis

Marijuana Users Have ‘Enhanced Cognitive Abilities,’ Large Federally Funded Study Shows

Marijuana users have “superior performance across multiple cognitive domains,” according to a new large-scale study funded by the U.S. federal government, with the effects of cannabis on cognition “presented concurrently across a range of brain systems.”

The research, published this month as a preprint by Nature Portfolio, analyzed brain imaging and cognitive data from 37,929 participants in the United Kingdom aged between 44 and 81 years old. The team found that cannabis consumers consistently outperformed non-users on a range of cognitive tests—suggesting that marijuana use may be linked to brain network patterns typically observed in younger individuals.

“These findings suggest that cannabis use may be associated with a deceleration of neural aging processes and the preservation of cognitive function in older adults,” the paper says.

“We speculate that cannabinoids and endocannabinoids may exert neuroprotective effects during aging by preserving an optimal balance between functional segregation and integration—an essential feature for maintaining specialized processing and efficient information transfer across brain networks,” wrote the researchers, who are from the Georgia Institute of Technology, Emory University, Georgia State University, University of Colorado, University of Chinese Academy of Sciences and Tri-Institutional Center for Translational Research in Neuroimaging and Data Science.

The authors of the study, which was supported by National Science Foundation and National Institutes of Health grants, noted that as marijuana laws evolve and societal attitudes shift, researchers are uncovering a more complex picture of the drug’s effects, particularly among older adults.

Legalization, increased permissiveness, and recognition of therapeutic potential have contributed to a marked rise in marijuana consumption among the study population, the authors said. They pointed out that older adults now represent the fastest-growing group of cannabis users, increasingly using it to manage chronic physical and mental health conditions.

Keep reading

Trump DOJ Asks Supreme Court To Uphold Ban On Marijuana Users Owning Guns

Amid a series of legal challenges, the Trump administration is asking the U.S. Supreme Court to take up a case on the federal government’s ban on users of marijuana and other illegal drugs from owning firearms and uphold the prohibition, saying it is consistent with the 2nd Amendment.

To that end, the DOJ solicitor general is urging SCOTUS to hear one of five relevant cases to resolve conflicting lower court decisions on gun rights for cannabis consumers.

With the multiple competing legal cases resulting in differing rulings in federal appeals courts across the country, DOJ last week requested that SCOTUS review one in particular that it described as “archetypal” of the issue related to federal code 922(g)(3), which precludes users of unlawful drugs from having guns or ammo.

The case “presents an important Second Amendment issue that affects hundreds of prosecutions every year: whether the government may disarm individuals who habitually use unlawful drugs but are not necessarily under the influence while possessing a firearm,” U.S. Solicitor General D. John Sauer, an appointee of President Donald Trump, said.

The solicitor general reiterated his position that, despite recent appeals court decisions calling into question the constitutionality of the firearms ban for people who use cannabis—even in compliance with state law—the restriction is nevertheless lawful.

Some lower courts have said the government’s blanket ban on gun and ammunition possession infringes on the Second Amendment—at least as applied to certain individual cases—because there’s no historical justification for such a broad restriction on an entire category of people.

But over recent years, various federal district and appeals courts have take differing approaches to the issue. As DOJ argued in its latest filing in the case, “the question presented is the subject of a multi-sided and growing circuit conflict.”

“The petition for a writ of certiorari [filed by Sauer in June] identified three sides of that conflict: The Seventh Circuit has upheld Section 922(g)(3); the Eighth Circuit has held it violates the Second Amendment unless the government can make a case-by-case showing justifying the drug user’s disarmament; and the Fifth Circuit has held that it generally violates the Second Amendment unless the drug user was intoxicated while possessing the firearm.”

“Since then, the conflict has deepened,” it said, referring to several other cases on the issue that are pending before the high court. And DOJ wants SCOTUS to focus on one case in particular to resolve what it called a “four-way circuit conflict”: U.S. v. Hemani.

One reason DOJ could be focused on the justices taking up Hemani in particular is that the defendant in that case is not only a cannabis user but also a user of cocaine who’s sold drugs in the past, according to court findings, which could make him less sympathetic in the eyes of the court. Defendants in the other cases were merely found in possession of both a firearm and marijuana.

Lawyers for the defendant in Hemani argued in a brief last month that the high court should decline the case.

But in its reply brief submitted to SCOTUS this week, the Justice Department said that “this case is the best vehicle available.”

Keep reading

Government-Backed Study From Japan Finds No Evidence That Marijuana Is A ‘Gateway Drug’

A new study looking into patterns of drug use in Japan casts further doubt on the notion that marijuana is a gateway drug, concluding that cannabis use in the country usually comes after people first use alcohol and tobacco, and that they rarely go on to use other substances.

Published this month in the journal Neuropsychopharmacology Reports, the research—which authors describe as “one of the largest and most significant studies on community-based cannabis users in Japan to date”—also found that nearly half of respondents who reported marijuana as their third drug “did not go on to use other substances afterward.”

“Cannabis use in Japan typically follows alcohol and tobacco, and rarely leads to further drug use,” concludes the report, which was supported by the Japanese Clinical Association of Cannabinoids and the government’s Ministry of Health, Labour and Welfare. “These findings challenge the gateway hypothesis in the Japanese context.”

The research acknowledges that cannabis “is often labeled a ‘gateway drug,’” but it notes that “strong causal evidence for progression to other substances is limited.”

Its findings suggest that rather than cannabis use itself leading to other drug use, “shared vulnerabilities”—involving factors like age, educational background and socioeconomic status—”and strict drug policies may shape these patterns.”

The study consisted of an anonymous survey conducted in January 2021, asking 3,900 people in Japan who had used cannabis in their lifetimes about other substance use. Researchers then analyzed the data to assess the chances of people using other drugs after trying marijuana.

“Rather than implying a causal gateway effect of cannabis use,” authors wrote, “results highlight the importance of considering the broader life context in which substance use occurs. Social determinants such as age cohort, educational background, and socioeconomic position appear to shape patterns of substance progression independently of the pharmacological properties of cannabis.”

Authors’ assessment of the responses found that “Odds for subsequent use of alcohol, tobacco, methamphetamine, and other illicit drugs after cannabis use were 1.25, 0.77, 0.08, and 0.78, respectively, suggesting low probabilities of progression.”

Keep reading

This Saturday Marks 88 Years of Federal Marijuana Prohibition — It’s Time To End It

Saturday, August 2nd, marks the 88th anniversary of the signing of the Marihuana Tax Act, the first federal marijuana prohibition law.

Since its inception, the criminalization of the marijuana plant and the stigmatization of those who consume it has been predicated almost entirely upon the promotion of gross exaggerations, racial stereotypes, and outright lies.

For instance, a July 6, 1927 story in the New York Times, headlined “Mexican Family Goes Insane,” farcically claimed: “A widow and her four children have been driven insane by eating the marihuana plant, according to doctors, who say there is no hope of saving the children’s lives and that the mother will be insane for the rest of her life.”

An academic paper titled “Marijuana,” published in 1933 in The Journal of Law and Criminology, similarly made over-the-top allegations about the plant’s supposed dangers. The authors wrote, “The inevitable result [of consuming cannabis] is insanity, which those familiar with it describe as absolutely incurable, and, without exception ending in death.”

In 1937, Harry J. Anslinger — America’s first ‘Drug Czar’ — lobbied Congress to ban cannabis nationwide. He did so over the staunch objections of the American Medical Association, which disputed the government’s false claims that cannabis use invariably induced violence, insanity, and death. Undeterred by the AMA’s opposition, Anslinger relied almost entirely upon racist rhetoric to persuade lawmakers. “There are 100,000 total marijuana smokers in the U.S., and most are Negroes, Hispanics, Filipinos, and entertainers. Their Satanic music, jazz and swing, result from marijuana use,” he asserted. “This marijuana causes white women to seek sexual relations with Negroes, entertainers, and any others.”

Fast-forward to 1971. That’s when the Nixon administration declared drug abuse to be “public enemy number one.” The lynchpin of this campaign was stamping out the use marijuana, which Congress had just classified as a Schedule I controlled substance — the strictest federal category available. Yet, privately, Nixon acknowledged that he did not think cannabis was “particularly dangerous,” and he lamented the “ridiculous” penalties faced by those arrested for possessing it.

Nonetheless, his administration publicly doubled down on the mythical marijuana threat for its own political gain. As his domestic policy chief, John Ehrlichman, later acknowledged, “We couldn’t make it illegal to be either against the (Vietnam) war or Black,” but we could get “the public to associate the hippies with marijuana and Blacks with heroin.”

By “criminalizing both heavily,” Ehrlichman explained, “we could disrupt those communities. We could arrest their leaders, raid their homes, break up their meetings, and vilify them night after night on the evening news.”

“Did we know we were lying about the drugs?” he asked. “Of course we did.”

Keep reading

Marijuana Prohibition Is And Always Has Been A Sham

Since its inception, efforts to criminalize the marijuana plant and stigmatize those who consume it have been predicated almost entirely upon gross exaggerations, racial stereotypes, and outright lies.

The initial push for cannabis criminalization, which began in earnest more than a century ago, had little to do with promoting public health or safety. Instead, the decision to target and prosecute cannabis users was fueled by xenophobia and media sensationalism.

For instance, a July 6, 1927 story in the New York Times, headlined “Mexican Family Goes Insane,” farcically claimed: “A widow and her four children have been driven insane by eating the marihuana plant, according to doctors, who say there is no hope of saving the children’s lives and that the mother will be insane for the rest of her life.”

An academic paper titled “Marijuana,” published in 1933 in The Journal of Law and Criminology, similarly made over-the-top allegations about the plant’s supposed dangers. The authors wrote, “The inevitable result [of consuming cannabis] is insanity, which those familiar with it describe as absolutely incurable, and, without exception, ending in death.”

In 1937, Harry J. Anslinger — America’s first ‘Drug Czar’ — successfully lobbied Congress to ban cannabis nationwide. He did so through the continuous use of racist rhetoric. “There are 100,000 total marijuana smokers in the U.S., and most are Negroes, Hispanics, Filipinos, and entertainers. Their Satanic music, jazz and swing, result from marijuana use,” he asserted. “This marijuana causes white women to seek sexual relations with Negroes, entertainers, and any others.”

Fast-forward to 1971. That’s when the Nixon administration declared drug abuse to be “public enemy number one.” The lynchpin of this campaign was stamping out the use of marijuana, which Congress had just classified as a Schedule I controlled substance — the strictest federal category available. Yet, privately, Nixon acknowledged that he did not think cannabis was “particularly dangerous,” and he lamented the “ridiculous” penalties faced by those arrested for possessing it.

Keep reading

Pew Poll: Few Americans Support Feds’ Blanket Prohibition of Marijuana

Eight-seven percent of Americans say that marijuana ought to be legal for either medical or adult use, according to nationwide polling compiled by the Pew Research Center.

The results are consistent with those of prior Pew polls finding that only about ten percent of US adults support a blanket policy of cannabis criminalization.

“The federal government’s ‘Flat Earth’ position on marijuana policy is remarkably out of step with both scientific and public consensus,” NORML’s Deputy Director Paul Armentano said. “Federally elected officials who refuse to take action to end cannabis criminalization do so at their own political peril.”

Fifty-four percent of respondents said that cannabis should be legal for both medical and adult use, while 33 percent of those surveyed supported medical marijuana legalization only. Consistent with prior polls, support for legalizing cannabis is strongest among liberal-leaning and younger voters (those ages 18 to 29), and it is weakest among more politically conservative-leaning voters and those over the age of 75.

Keep reading

Anti-Marijuana Physician Who Criticized Rescheduling Proposal Joins Trump White House’s Drug Office

The White House Office of National Drug Control Policy (ONDCP) is adding to its team a medical professional who has linked marijuana use to suicide, advocated against a Florida legalization measure and criticized health agencies’ move to reschedule cannabis.

She has also said it is an “insult” to refer to cannabis as “medical.”

Roneet Lev—an emergency medicine and addition physician who previously served as chief medical officer at ONDCP under the first Trump administration—announced on Monday that she’ll be rejoining the office for the chance to “save lives on a much bigger scale.”

While she didn’t mention marijuana in the announcement on her podcast “High Truths on Drugs and Addiction,” Lev has previously spoken extensively about her issues with cannabis—describing it as an understated public health risk and arguing that commercial interests are the driving force behind the legalization movement.

In one episode of her podcast from June 2024, she dedicated over an hour to a discussion with prohibitionist advocates about the marijuana rescheduling process that was initiated under the Biden administration, making clear she strongly disagrees with the top federal health agency’s recommendation to move cannabis from Schedule I to Schedule III of the Controlled Substances Act (CSA).

She said that people who are accepting the scientific findings that led to the recommendation,”including some in the medical community,” are “drinking that same Kool Aid again” with marijuana as they did with prescription opioids. And she claimed that the U.S. Department of Health and Human Services (HHS) produced a flawed report on cannabis, with mistakes in “like every single sentence.”

“When it comes to marijuana, the harms are right in front of our eyes—but we ignore the data and follow the industry talking points just like we did in the oxycontin days,” Lev said during the segment, which featured prominent prohibitionists such as Bertha Madras, who also previously served as an ONDCP official.

The revised review process that HHS relied on to reach its Schedule III determination for marijuana posts a “threat to the entire way of approving medications and to the medical community at large,” Lev said, adding that her primary contention is the idea that cannabis possesses medical value.

Keep reading

7 Chinese nationals charged in MASSIVE money laundering, human smuggling, drug trafficking operation

Seven Chinese nationals have been charged in connection to a conspiracy to cultivate as well as distribute marijuana in the Northeastern United States. They undertook this operation by using a network of single-family houses in Massachusetts as well as Maine, according to the Department of Justice (DOJ).  

A press release from the DOJ on the charges stated that Jianxiong Chen, 39; Yuxiong Wu, 36; Dinghui Li, 38; Dechao Ma, 35; Peng Lian Zhu, 35; Hongbin Wu, 35; and Yanrong Zhu, 47 were all charged in connection to the network distributing the drugs around the Northeast. Six of the defendants were taken into custody earlier this week, with Yanrong Zhu still on the run as a fugitive.  

Most of the Chinese nationals have been charged with money laundering as well as conspiracy, and some were also charged with bringing assisting with bringing foreign nationals to the US illegally.

US Attorney Leah B. Foley said of the charges, “This case pulls back the curtain on a sprawling criminal enterprise that exploited our immigration system and our communities for personal gain. These defendants allegedly turned quiet homes across the Northeast into hubs for a criminal enterprise – building a multi-million-dollar black-market operation off the backs of an illegal workforce and using our neighborhoods as cover. That ends today.” 

The DOJ further stated, “According to the charging documents, from in or about January 2020, the defendants allegedly owned, operated or partnered with a network of interconnected grow houses in Massachusetts and Maine to cultivate and distribute kilogram-sized quantities of marijuana in bulk. Specifically, the enterprise allegedly operated grow houses in Braintree, Mass.; Melrose, Mass.; and Greenfield, Mass., among other locations in Massachusetts, Maine and elsewhere.” 

Keep reading

Newsom Protests ICE Raid on Marijuana Farm Allegedly Found Using Child Labor

California Gov. Gavin Newsom protested against an Immigration and Customs Enforcement (ICE) raid on a marijuana farm in his state this week that was allegedly found to have been using child labor.

Newsom reposted a video of the raid, calling President Donald Trump the “real scum” for enforcing the law.

U.S. Customs and Border Protection Commissioner Rodney Scott alleged that the farm had been found employing not only illegal aliens, but also “juveniles.”

Newsom was, in effect, trying to protect child labor.

The governor returned Thursday from a two-day swing to South Carolina, where he is testing the waters for a presidential run in three years’ time by introducing himself to voters in rural counties.

Keep reading

Study: CBD Inhibits Osteosarcoma by Targeting Tumor-Driving Inflammation

“Osteosarcoma remains a therapeutic challenge due to its aggressive behavior and high metastatic potential, necessitating exploration of novel treatment modalities”, states the study’s abstract. “Cannabidiol (CBD), a non-psychoactive phytocannabinoid with emerging anticancer properties, has shown promise in preclinical cancer models. However, its mechanisms of action in osteosarcoma remain incompletely understood.”

With that in mind, “This study systematically investigates the antitumor effects of CBD on osteosarcoma and elucidates its molecular targets within the TNF-α/NF-κB/CCL5 signaling axis.”

Conducted by researchers at Shandong University and Harbin Medical University, researchers used cell-based assays and a mouse model, finding that CBD suppressed osteosarcoma cell proliferation, migration, and invasion, while also reducing tumor growth in vivo.

The team identified that CBD binds directly to the NF-κB subunit p65, blocking its ability to activate transcription of the chemokine CCL5. This disruption also interfered with a previously unrecognized positive feedback loop between p65 and CCL5, which helps sustain inflammatory signaling in osteosarcoma cells. By targeting this loop, CBD not only inhibited tumor-promoting inflammation but also weakened the cancer’s ability to proliferate and spread.

The researchers used a combination of molecular docking, protein-binding assays, and gene expression analysis to confirm CBD’s direct interaction with the p65 protein and its downstream effects.

Keep reading