Tag: mosquitos

Hemp Shows Strong Antiviral Activity Against Japanese Encephalitis Virus

The research, published by Arch Virol and conducted by scientists from Chung-Ang University, The Catholic University of Korea, Kyungpook National University and Gyeongkuk National University, analyzed whether extracts from hemp roots and stems could limit viral activity in cell models.

The team prepared ethanol extracts and organic solvent fractions from hemp material, first identifying non-toxic concentration ranges through standard cytotoxicity assays. Several of these fractions showed strong virucidal effects, but the hexane and chloroform fractions stood out for producing the most pronounced suppression of viral activity.

When these highly active fractions were applied after cells had already been infected, researchers observed a sharp reduction in viral replication. Both JEV mRNA and the viral E protein dropped substantially, indicating that the post-treatment approach directly interfered with the virus’s ability to grow. By contrast, applying the fractions before viral exposure—or at the same time as exposure—did not offer meaningful protection, suggesting the compounds work most effectively once infection is underway.

Further chemical analysis identified several known hemp-derived molecules within the active fractions, and one compound in particular, stigmasterol, emerged as a key antiviral candidate. In follow-up tests, stigmasterol demonstrated both virucidal action and direct antiviral activity. It disrupted viral entry during infection and suppressed viral growth afterward, again reducing JEV mRNA and E protein expression to significant levels.

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The Weaponization of Gene-Edited Mosquitoes

There are several dimensions to the mosquito crisis. The release of gene-edited male mosquitoes, coupled with the development of a dengue and malaria vaccine

But that is but the tip of the iceberg.

According to F. William Engdahl in 2018, the weaponization of insects is on the drawing board of the Pentagon:

There is strong evidence that the Pentagon, through its research and development agency, DARPA, is developing genetically modified insects that would be capable of destroying agriculture crops of a potential enemy.

The claim has been denied by DARPA, but leading biologists have sounded the alarm on what is taking place using new “gene-editing” CRISPR technology to in effect weaponize insects.

It’s like a 21st Century update of the Biblical plague of locusts, only potentially far worse.

Under the DARPA project, Genetic Alteration Agents or viruses will be introduced into the insect population to directly influence the genetic makeup of crops.

DARPA plans to use leaf hoppers, white flies, and aphids to introduce select viruses into crops. Among other dubious claims they say it will help farmers combat ‘climate change’.

What no one can answer, especially as neither the Pentagon nor the US FDA are asking, is how will the genetically engineered viruses in the insects interact with other microorganisms in the environment?

If crops are constantly being inundated by genetically modified viruses, how could this could alter the genetics and immune systems of humans who depend on the crops?

See F. William Engdahl, Why Is the Pentagon “Weaponizing Insects”? October 30, 2018

This posting includes excerpts from Jordan Shachtel, Amie Wek and Jamie White followed by the article of F. William Engdahl.

The World Mosquito Program plans to release five billion mosquitoes into Brazil.

“And the hope is they will help save lives. [Once] you see the reductions in disease transmission, it doesn’t seem like a horror movie any more,” Scott O’Neill, director of the World Mosquito Program” (CBC, April 2023)

Implemented concurrently with the influx of 5 billion friendly mosquitoes, Brazil approved in March 2023 a vaccine against dengue.

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Cannabis extract proves to be highly effective at killing the most dangerous animals in the world

Every year, mosquito-borne diseases cut short more than a million lives across the globe, outpacing every other animal threat to humanity. The rising toll has public-health teams scrambling for fresh combat tools, especially as traditional chemical sprays lose their edge.

That loss stems from two hard truths. First, the very pyrethroid insecticides that once worked wonders now linger in soil and water, nudging delicate ecosystems off balance.

Second, mosquitoes adapt fast. Larvae soaking in tainted puddles and adults drifting through treated neighborhoods increasingly shrug off doses that once killed them.

Controlling the pests at their waterborne stage is vital, yet options that stay potent without harming everything else remain limited.

Cannabis, CBD, and mosquitoes

Recent research published in the journal Insects points to a solution hiding in plain sight: the hemp plant, Cannabis sativa.

After air-drying and grinding ordinary hemp leaves, scientists at The Ohio State University led by Erick Martinez Rodriguez extracted cannabidiol (CBD) and added the concentrate to cups of water teeming with yellow fever mosquito larvae.

Within 48 hours, both a strain that laughs at common insecticides and a non-resistant strain were wiped out.

“Mosquitoes are one of the deadliest animals in the world, mainly because as adults they serve as vectors of disease,” Rodriguez explained.

From resistance to vulnerability

Two important findings jumped out. The first was total mortality: every mosquito larva exposed to sufficient CBD died by the two-day mark, regardless of its genetic armor.

The second was efficiency. While industrial chemicals often push resistance higher with every generation, CBD’s effect cut straight through those defenses. Doses varied, but even modest concentrations proved lethal to all mosquito larvae.

“If you compare the amount of hemp extract needed to kill 50 % of the population to other synthetic conventional insecticides, it is on the high side, but when you compare it side by side to other natural extracts we have tested in our lab, only a relatively low amount is required to produce high mortality values in larvae,” said Martinez Rodriguez.

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Researchers Funded by Bill Gates Turn Mosquitoes into ‘Flying Syringes’ to Deliver Vaccines

Researchers at Leiden University Medical Center, backed by the Bill & Melinda Gates Foundation, have developed a new method of delivering malaria vaccines using genetically modified mosquitoes as “flying vaccinators.”

The Blaze reports that in a study published in the New England Journal of Medicine, scientists have demonstrated the effectiveness of using mosquitoes as “flying syringes” to vaccinate humans against malaria. The research, conducted at the Leiden University Medical Center (LUMC) in the Netherlands with funding from the Bill & Melinda Gates Foundation, represents a new and potentially worrying advancement in vaccine technology.

The study involved genetically modifying malaria parasites to stop developing after a certain period of time in the human body. The modified parasites, named GA1 and GA2, were designed to prime the immune system without causing a full-blown malaria infection. Researchers then infected mosquitoes with these engineered parasites and allowed them to bite human test subjects in a controlled setting.

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EPA Authorizes Release of 2 Billion More GMO Mosquitoes as Reports of Malaria Surface in States That Already Released Them

GE mosquitoes created by biotechnology company Oxitec have been released in the U.S., even though the long-term effects could be disastrous.

Oxitec is using Aedes aegypti (A. aegypti) mosquitoes for this real-world experiment, the species known to carry yellow fever, dengue fever, chikungunya, Zika, West Nile and Mayaro, a dengue-like disease.

Oxitec genetically engineered the males to carry a “genetic kill switch,” such that when they mate with wild female mosquitoes, their offspring inherits the lethal gene and cannot survive or reproduce in the wild.

In the U.S., Oxitec is marketing the insects as Oxitec Friendly mosquitoes, trying to put a non-threatening name on a reckless project that could quickly backfire.

It may even be too late, as the GE mosquitoes have already been released in multiple locations.

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THIS WILL NOT END WELL: Communist Chinese Scientists Explore Using MOSQUITOS to Distribute VACCINES, Could Create Dangerous MUTANT Insects Instead

Designing a killer virus evidently was just a little test run for the Chicoms. Now they might unleash mankind’s most notorious insect to supposedly “vaccinate” wildlife and reduce viral infections.

Hard to imagine any unintended consequences will occur. It’s not like mosquitos spread nasty infections like Yellow Fever, Malaria, West Nile, and Dengue Fever to humans.

The South China Morning Post reported Wednesday that Chinese scientists claim they found a way to turn the disease-carrying nuisance into an indispensable ally of all humanity. Of course, this required them to create a few genetically modified insects.

Here are their findings. No question they applied this trial with the same rigor and caution as their other gain of function research projects:

“The researchers found that bites in wildlife from genetically modified mosquitoes triggered a strong, long-lasting immune response. Once immunized, the animals resisted infections, thus helping to prevent the early spread of many viruses, including the once widespread Zika virus (ZIKV).”

“In their study, the researchers used CYV as a vaccine vector to construct a chimeric vaccine, which contains proteins from a different virus. They took several proteins from CYV and inserted them into ZIKV cells to create the CYV-ZIKV virus, which was not infectious (in animals, human impact unknown). CYV-ZIKV could replicate efficiently in mosquitoes and be secreted in saliva, they said.”

But don’t worry about this virus reaching mosquitos in the wild. Chinese scientists assure us they took care of the problem. You can trust the Chicoms, right?

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‘Super’ mosquitoes have now mutated to withstand insecticides, scientists say

One of the most vilified pest species on the planet continues to outsmart the ways in which humans attempt to get rid of them.

“Super” mosquitoes have evolved to withstand insecticides, according to new research — and the most “sobering” finding is the high rate in which a species known for carrying disease has developed mutations.

Researchers at the National Institute of Infectious Diseases in Japan studied mosquitoes in dengue-endemic areas in Vietnam and Cambodia and found that they harbor mutations that endow them with strong resistance to common insecticides, according to a study published in Science Advances on Wednesday.

One of the most concerning mutations appeared in about 78% in collected specimens of Aedes aegypti — one of the most infamous species of mosquito and a major vector of dengue, yellow fever and Zika virus, according to the study.

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Genetically Modified Mosquitoes Vaccinate a Human

A box full of genetically modified mosquitoes successfully vaccinated a human against malaria in a trial funded by the National Institutes of Health (NIH).

The study involved about 200 hungry mosquitos biting a human subject’s arm. Human participants placed their arms directly over a small box full of the bloodsuckers.

“We use the mosquitoes like they’re 1,000 small flying syringes,” said researcher Dr. Sean Murphy, as reported by NPR.

Three to five “vaccinations” took place over 30-day intervals.

The mosquitoes gave minor versions of malaria that didn’t make people sick, but gave them antibodies. Efficacy from the antibodies lasted a few months.

“Half of the individuals in each vaccine group did not develop detectable P. falciparum infection, and a subset of these individuals was subjected to a second CHMI 6 months later and remained partially protected. These results support further development of genetically attenuated sporozoites as potential malaria vaccines,” researchers concluded.

Carolina Reid was one of twenty-six participants in the study.

“My whole forearm swelled and blistered. My family was laughing, asking like, ‘why are you subjecting yourself to this?’”

Reid enjoyed her experience so much that she says she wants to participate in as many vaccine trials as she can. For this research, each participant received $4,100 as an incentive.

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Florida Approves Release of Billions of GMO Mosquitoes

Overlooking potential public health risks, lingering scientific questions, and deficient public data, the Florida Department of Agriculture and Consumer Services (FDACS) approved the extension of Oxitec’s two-year field trial on Wednesday, which includes releasing several billion more genetically engineered (GE) mosquitoes into the Florida Keys — one of Florida’s most ecologically sensitive areas.

FDACS’ approval comes on the heels of U.S. Environmental Protection Agency (EPA) granting the British biotechnology company Oxitec a two-year extension for its Experimental Use Permit for the release of a GE version of the species Aedes aegypti across Monroe County, Florida.

“FDACS should have required Oxitec to cease claiming as ‘confidential business information’ their data on the human health and environmental effects of the release of the mosquitoes,” said Jaydee Hanson, Policy Director at Center for Food Safety. “In Spain, when Oxitec withheld the data, the Spanish government told Oxitec to make public the health and environmental safety effects of their genetically engineered insect. Florida should have done the same. Moreover, FDACS should not have allowed a second major release without making public the data from the first trial and having it reviewed by unbiased scientists in the field.”

FDACS’ approval came despite unresolved public health and environmental concerns raised by scientists, public health experts and environmental groups about potential impacts of the release. The data from Florida’s 2021 field trial release of genetically engineered mosquitoes in the Florida Keys still has not been made public or reviewed by independent scientists.

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Mosquitoes With Synthetic DNA Scheduled For California Release

In the mosquito breeding rooms of British biotech company Oxitec, scientists line up fresh eggs, each the size of a grain of salt. Using microscopic needles, the white-coated researchers inject each egg with a dab of a proprietary synthetic DNA.

For four days, Oxitec technicians care for the eggs, watching for those that hatch into wriggling brown larvae. Those “injection survivors,” as the company calls them, face a battery of tests to ensure their genetic modification is successful.

Soon, millions of these engineered mosquitoes could be set loose in California in an experiment recently approved by the federal government.

Oxitec, a private company, says its genetically modified bugs could help save half the world’s population from the invasive Aedes aegypti mosquito, which can spread diseases such as yellow fever, chikungunya and dengue to humans. Female offspring produced by these modified insects will die, according to Oxitec’s plan, causing the population to collapse.

“Precise. Environmentally sustainable. Non-toxic,” the company says on its website of its product trademarked as the “Friendly” mosquito.

Scientists independent from the company and critical of the proposal say not so fast. They say unleashing the experimental creatures into nature has risks that haven’t yet been fully studied, including possible harm to other species or unexpectedly making the local mosquito population harder to control.

Even scientists who see the potential of genetic engineering are uneasy about releasing the transgenic insects into neighborhoods because of how hard such trials are to control.

“There needs to be more transparency about why these experiments are being done,” said Natalie Kofler, a bioethicist at Harvard Medical Schoolwho has followed the company’s work. “How are we weighing the risks and benefits?”

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