Rising cancer rates in Iowa linked to agricultural chemicals like glyphosate, atrazine and chlorpyrifos

Iowa is grappling with a stark and troubling reality: the state has recently been identified as having the fastest-growing cancer rates in the nation. This alarming increase in cancer rates has prompted a closer examination of environmental factors contributing to this troubling trend. A 2024 report by the Iowa Department of Public Health reveals that cancer rates in rural areas of the state, where pesticide use is more intensive, are significantly higher compared to urban regions. The study highlights that communities with heavy agricultural activity have seen a rise in cases of leukemia, lymphoma and breast cancer.

Iowa’s cancerous frontier dominated by glyphosate, atrazine, nitrates, chlorpyrifos

Iowa has seen a dramatic rise in cancer diagnoses, with 486 new cases per 100,000 people in 2024, surpassing the national average of 444 cases per 100,000. The estimated number of new cancer cases this year stands at 21,000, with approximately 6,100 deaths expected. This surge in cancer rates is particularly concerning given that Iowa’s cancer incidence now outpaces other states facing their own unique health challenges, such as industrial pollution, smoking and high obesity rates.

The state, known for its expansive agricultural landscape, relies heavily on pesticides to protect crops and maximize yields. The state’s agriculture sector uses a variety of chemical treatments, including herbicides, insecticides and fungicides. The most commonly used pesticides in Iowa include glyphosate, atrazine and chlorpyrifos.

Glyphosate, a broad-spectrum herbicide, is used extensively in the cultivation of corn and soybeans. Glyphosate disrupts the shikimate pathway of gut microbes and has been linked to an increased risk of non-Hodgkin lymphoma, a type of cancer that affects the lymphatic system.

Atrazine, another herbicide, is frequently applied to control weeds in cornfields. Atrazine has been associated with endocrine disruption, which may increase the risk of certain cancers. Studies have found atrazine is responsible for alterations in the HPG axis, damaging reproductive function. It also has estrogenic effects, leading to  aromatase activation, including inhibition of PDE4 and altered hormone secretion — precursors to breast cancer.

Chlorpyrifos, an insecticide, is employed to combat pests in a variety of crops. Chlorpyrifos, although banned for residential use, is still permitted in agriculture and has been linked to developmental and cancer risks.

Nitrates, which are key ingredient in fertilizers used across Iowa, are linked to colorectal cancer.

In addition to herbicides, insecticides and fertilizer, radon — a naturally occurring radioactive gas — also poses a significant risk. Radon is the leading cause of lung cancer among non-smokers and is particularly problematic in Iowa, where levels are six times higher than the national average. Radon can seep into homes undetected, further exacerbating health risks for residents.

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69 Biomarkers of Pesticides, Pollutants Found in Hair Analyses of French Children

Using mass spectrometry techniques, researchers in Luxembourg and France detected 69 biomarkers of pollutants and pesticides — 12 of which are banned — in hair samples from over 200 French children.

This study, published in Environment International, is the first to target over 150 biomarkers in a single hair sample, which “represents the most comprehensive assessment of chemical exposome in humans,” the authors say.

All children in the study were 3.5 years old and recruited from the Étude Longitudinale Française depuis l’Enfance (ELFE), French Longitudinal Study since Childhood, cohort in the country of France, a major pesticide consumer in Europe.

The ELFE survey is a joint project between the French Institute for Demographic Studies and the National Institute of Health and Medical Research, which provides the first comprehensive national scientific investigation of children in France by following them from birth to adulthood.

Through analysis of hair samples from children in the ELFE cohort, this study evaluates pesticide exposure and compares it with prenatal exposure data from their mothers while also, according to the scientists, “investigat[ing] the roles of children’s biological sex and geographical differences as possible determinants of exposure.”

Exposure to pesticides during early childhood poses significant health risks. In assessing 32 chemical families through liquid chromatography-tandem mass spectrometry and gas chromatography-tandem mass spectrometry in 222 hair samples, exposure markers can be identified in children from the ELFE cohort.

Biomarkers, according to the U.S. Environmental Protection Agency (EPA), are “measurable substances or characteristics in the human body that can be used to monitor the presence of a chemical in the body, biological responses or adverse health effects.”

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Pesticides Designed to ‘Edit’ the Genes of Plants, Animals, Insects — and Humans?

We’re used to gene editing being something that’s done in controlled and contained conditions in the lab, with just the final product being unleashed in the environment.

But coming down the pipeline are pesticides designed to “edit” the genes of organisms out of doors, in the uncontrolled conditions of the open environment.

Applied by spraying, irrigation, or soil pellets, these outdoor-use genetic pesticides are claimed to be more environmentally friendly than chemical pesticides.

The problem is that these genetic pesticides could also “edit” the genes of what scientists call non-target organisms — i.e., people, animals and insects in the environment could become collateral damage.

“Editing” these organisms’ genes means silencing or disrupting their normal functioning.

And the deregulation of gene editing that is occurring and being aggressively promoted around the globe means that these products could be used in open fields with no prior risk assessment, traceability, or monitoring.

Sounding the alarm about this “Wild West” scenario is a new study by an international team of scientists.

The study, based on computer predictive modeling, found that exposure to a CRISPR/Cas gene-editing pesticide could unintentionally alter the genes of a wide assortment of non-target organisms, with potentially serious or even fatal consequences.

And leading the list of potential victims of unintended gene editing are humans.

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Government scientist investigating mystery brain disease ‘banned’ from researching outbreak – stoking fears of a cover-up

A top scientist who advises the Canadian Government said he was blocked from studying a freak outbreak of a mysterious and deadly brain illness in young adults and teenagers. 

More than 200 New Brunswick residents have bizarrely developed a dementia-like disorder that causes vivid hallucinations, an inability to talk and write, memory lapses and even physical paralysis.

While the disease has baffled doctors, local health officials put the outbreak down to misdiagnosis, concluding that most patients in fact suffered common illnesses like dementia and cancer

Now, damning evidence has come to light that suggests health chiefs may have purposefully blocked investigations into other potential causes — namely, exposure to toxic pesticides. 

In leaked emails sent between Dr Michael Coulthart, a microbiologist, and members of Canada’s public health agency (PHAC), Dr Coulthart said he was ‘essentially cut off’ from being involved in the research.

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Study Finds 80 Percent Americans Exposed to Fertility-Lowering Chemicals in Cheerios, Quaker Oats

According to a recent study, four in five Americans tested positive for an agricultural chemical found in several wheat and oat products, including brands like Cheerios and Quaker Oats.

The peer-reviewed study, published in the JESEE journal on Feb. 15, looked at urine samples from American citizens to determine their exposure to chlormequat chloride—a plant growth chemical. Exposure to the chemical can result in lower fertility and harm developing fetuses even at doses below acceptable levels set by regulators. Researchers detected chlormequat in 80 percent of urine samples collected between 2017 and 2023, with “a significant increase in concentrations for samples from 2023.”

The chemical was detected in “92 percent of oat-based foods purchased in May 2023, including Quaker Oats and Cheerios,” said the Environmental Working Group (EWG), which conducted the study.

Out of 25 conventional oat products tested, 23 had “detectable levels” of chlormequat. One in eight organic oat products had the chemical, while two in nine wheat products had low concentrations of chlormequat.

Researchers collected 96 urine samples, out of which 77 showed the presence of chlormequat. The numbers suggest that the subjects likely underwent “continuous exposure” to the chemical since chlormequat leaves the body about 24 hours after ingestion.

The frequency of the chemical in samples was observed to rise with time. In 2017, 69 percent of samples had chlormequat, which jumped to 74 percent in 2018-2022 and then to 90 percent in 2023.

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Yet Another Study Links Lower Sperm Count with Pesticides

A new review of existing studies on insecticides has found “sufficient evidence” that exposure to high levels of insecticides is associated with lower sperm concentration in men. The review focused on organophosphate (OP) and N-methyl carbamate (NMC) insecticides. The researchers said their systematic review and meta-analysis are the most comprehensive on this topic to date.

The paper, “Adult Organophosphate and Carbamate Insecticide Exposure and Sperm Concentration: A Systematic Review and Meta-Analysis of the Epidemiological Evidence,” was published in the journal Environmental Health Perspectives. It sought to answer the question, “What is the association between adult exposure to OP and NMC insecticides and sperm concentration?”

The researchers concluded that “the strength of evidence of an association between higher adult OP and NMC insecticide exposure and lower sperm concentration is sufficient enough to warrant concern, particularly in light of observed downward trends in semen quality.”

Although the paper acknowledges numerous factors that impact sperm concentration, such as age, nutrition, and lifestyle, they also point the finger at “reproductive toxicants in the environment,” particularly endocrine-disrupting chemicals.

“Reproductive toxicants are ubiquitous in the environment, and usually go unnoticed until unintended adverse effects are observed,” they write. “Pesticides are a prime example in that pesticides have known endocrine disrupting and reproductive effects but continue to be manufactured and widely applied, resulting in occupational and environmental exposures.”

Regarding occupational exposures, the review noted that workers exposed to toxins in the course of their job “generally experience higher exposures than the general population.” However, they also noted that because of widespread exposure to the chemicals in the environment, even a small magnitude of effect could have consequential impacts on sperm concentration at a population level.”

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Study Shows Pesticide Companies Hid Developmental Neurotoxicity Data From EU Regulators

A recently published study reveals that pesticide companies have failed to disclose data related to brain toxicity. What does this mean for toxicity data in other fields of research?

Recently, the U.S. Geological Survey acknowledged that at least 45% of the nation’s tap water is estimated to have one or more types of the chemicals known as per- and polyfluorinated alkyl substances, or PFAS, also known as forever chemicals. This is, unfortunately, just the latest in a string of similar admissions relating to water quality which have come to light in recent years.

As more Americans grapple with the reality that we are swimming in a soup of toxins and radiation, Europeans are becoming aware of the lack of transparency involving studies of pesticides, and potentially other toxins.

A study published in early June found that some studies of pesticides relating to developmental neurotoxicity (DNT) were submitted to the U.S. Environmental Protection Agency (EPA), but not to regulatory bodies within the European Union. It took between 14 and 21 years for EU regulators to become aware of these studies. Once they were aware of the data, they enacted new safety regulations in some cases and continue to evaluate necessary steps in others.

A DNT test typically exposes pregnant female rats to a pesticide to assess their offspring for neuropathological and behavioral changes. The tests have been useful for identifying chemicals which will cause DNT in humans.

The study was first reported on by The Guardian in collaboration with European outlets Bayerischer Rundfunk/ARD, Der Spiegel in Germany, SRF in Switzerland, and Le Monde in France. It has received little attention in the American media.

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EPA Refuses to Regulate Pesticide-Coated Seeds That Harm Pollinators

Last week, the U.S. Environmental Protection Agency (EPA) denied a legal petition by Center for Food Safety (CFS), Pesticide Action Network of North America and others, demanding that the agency fix its failure to regulate pesticide-coated seeds, which are known to be widely harming bees and other pollinators.

These crop seeds are coated with systemic insecticides known as neonicotinoids, the most widely used insecticides, and have devastating environmental effects.

CFS filed the rulemaking petition in 2017 that would close the loophole, but was forced to take take the agency to court when EPA failed to answer the petition as of late 2021.

Last week’s response is issued pursuant to a court-set deadline.

“We gave EPA a golden chance and a blueprint to fix a problem that has caused significant harm to people, bees, birds, and the environment — and it stubbornly refused,” said Amy van Saun, senior attorney with the Center for Food Safety. “It’s extremely disappointing and we’ll be exploring all possible next steps to protect communities and the environment from the hazard of pesticide-coated seeds, including a lawsuit challenging this decision.”

Crops grown from pesticide-coated seeds, such as corn, soybean and sunflower seeds cover over 150 million acres of U.S. farmland each year.

Neonicotinoids are taken up into the plant’s circulatory system as the plant grows, permeating leaf, pollen, nectar and other plant tissues. Neonicotinoids affect the central nervous system of insects, causing paralysis and death.

Sublethal impacts include impaired navigation and learning. As a result, beneficial insects, valuable pollinators and birds — including threatened and endangered species protected under the Endangered Species Act — are killed or injured.

For songbirds, ingesting just one neonic-coated seed can cause serious harm or death.

Additionally, more than 80% of the pesticide coating can leave the seed, contaminating the air, soil and waterways of surrounding environments. Most notably, clouds of neonicotinoid-laced dust released during planting operations have caused mass die-offs of honeybees and wild native bees.

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Pesticides Increase Transmission of Debilitating Snail Fever Affecting Hundreds of Millions of People

Widespread use of pesticides, including the world’s most used herbicide, glyphosate, can speed the transmission of the debilitating disease schistosomiasis (snail fever), while also upsetting the ecological balances in aquatic environments that prevent infections, a new study led by researchers at the University of California, Berkeley has found.

Schistosomiasis (also known as Snail Fever and Bilharzia) is a disease of poverty that leads to chronic ill-health, according to the World Health Organization. Infection is acquired when people come into contact with fresh water infested with the larval forms (cercariae) of parasitic blood flukes, known as schistosomes. The microscopic adult worms live in the veins draining the urinary tract and intestines. Most of the eggs they lay are trapped in the tissues and the body’s reaction to them can cause massive damage.

Schistosomiasis affects almost 240 million people worldwide, and more than 700 million people live in endemic areas. The infection is prevalent in tropical and sub-tropical areas, in poor communities without potable water and adequate sanitation.

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