Tag: dna

Dinosaur egg unearthed in perfect condition after 70M years— and it could hold genetic material

It was in egg-cellent condition.

Argentine paleontologists found a real diamond in the rough after happening across a perfectly preserved 70-million-year-old dinosaur egg during an excavation.

“It was a complete and utter surprise,” Gonzalo Leonel Muñoz, a Vertebrate paleontologist at the Bernardo Rivadavia Argentine Museum of Natural Sciences, told National Geographic of the “spectacular” find. “‘It’s not uncommon to find dinosaur fossils, but the issue with eggs is that they are much less common.”

The team of paleontologists was reportedly conducting an excavation campaign in the fossil-rich region of Río Negro, when they stumbled across the primeval embryo.

While dinosaur eggs had been excavated in the area before, finding one this well-preserved was super rare.

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First Peer-Reviewed Study Finds Direct Molecular Evidence of mRNA “Vaccine” Genomic Integration

For the first time in the peer-reviewed literature— we present direct molecular evidence that genetic material from a COVID-19 mRNA “vaccine” has integrated into the human genome.

In our sentinel peer-reviewed case report, Genomic Integration and Molecular Dysregulation in Aggressive Stage IV Bladder Cancer Following COVID-19 mRNA Vaccination—published in the International Journal of Innovative Research in Medical Science (John A. Catanzaro, Nicolas Hulscher, and Peter A. McCullough; a Neo7Bioscience–McCullough Foundation collaboration)—we describe a previously healthy 31-year-old woman who developed rapidly progressive stage IV bladder cancer within 12 months of completing a three-dose Moderna mRNA injection series.

Bladder cancer is exceedingly rare in young women, and such aggressive presentations are almost unheard of.

To investigate, we performed comprehensive multi-omic profiling, including plasma-derived circulating tumor DNA, whole-blood RNA, and urine exosome proteomics. What we uncovered was striking:

  • Direct genomic integration event: Within circulating tumor DNA, a host–vector chimeric read mapped to chr19:55,482,637–55,482,674 (GRCh38), in cytoband 19q13.42, positioned ~367 kb downstream of the canonical AAVS1 safe harbor and ~158 kb upstream of ZNF580 at the proximal edge of the zinc-finger (ZNF) gene cluster. This sequence aligned with perfect 20/20 bp identity to a segment (bases 5905–5924) within the Spike open reading frame (ORF) coding region (bases 3674–7480) of the Pfizer BNT162b2 DNA plasmid reference (GenBank accession OR134577.1).
  • Oncogenic driver hyperactivation (KRAS, NRAS, MAPK1, ATM, PIK3CA, SF3B1, CHD4) — unleashing uncontrolled proliferative and malignant signaling cascades.
  • Critical DNA repair pathway collapse (ATM, MSH2) — leaving the genome acutely vulnerable to instability, double-strand breaks, and catastrophic mutations.
  • Severe transcriptomic and proteomic disarray across plasma, blood, and urine biospecimens — consistent with systemic molecular breakdown.

Although the patient received only Moderna injections, the sequence aligned to Pfizer’s published BNT162b2 plasmid reference because Moderna has never deposited its proprietary plasmid in NCBI. Crucially, both Pfizer and Moderna vaccines encode the same prefusion-stabilized SARS-CoV-2 Spike protein and therefore share identical stretches of nucleotide sequence within the Spike ORF coding region. It is within one of these conserved regions that the integration was captured, producing the perfect 20/20 bp match to the Pfizer reference.

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‘Alien’ DNA found inside humans — it was inserted into our genes, bonkers new study claims

Is it the invasion of the genome snatchers?

Just in case the idea of aliens walking around in human skin suits wasn’t frightening enough. An outlandish study asserts that aliens might have abducted us and inserted genes into human DNA, with the fallout affecting potentially millions of people.

“Humanity may be undergoing genetic transformation,” lead researcher Dr. Max Rempel, the founder and CEO of the DNA Resonance Research Foundation, told the Daily Mail of the study, which has yet to be peer-reviewed.

Rempel came to this far-fetched-seeming conclusion by analyzing DNA from both regular people and those who have claimed to have been abducted by aliens. This comes following a spike in UFO sightings over the last year, making many fear that we are on the verge of some not-so-friendly close encounters.

The scientist specifically analyzed 581 complete families from the 1,000 Genomes Project, discovering ‘large sequences’ of DNA in 11 families that didn’t appear to correspond to either family.

These genetic aberrations entailed a bundle of 348 non-parental genetic variants. As the subjects were born before 1990, this ruled out human gene-editing technologies like CRISPR, which only emerged in 2013.

Rempel also analyzed 23andMe results from individuals who self-identify as alien abductees, discovering that some families showed evidence of non-parental markers.

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Immortal Monkeys? Not Quite, But Scientists Just Reversed Aging With ‘Super’ Stem Cells

In a discovery that may have profound impacts on aging, scientists in Beijing have taken a dramatic step toward what once seemed impossible: making old animals biologically young again. The study was published last month in the journal Cell.

By fortifying human stem cells with a gene long linked to longevity, they rejuvenated aged monkeys – improving memory, protecting bones, calming inflammation, and restoring youthful activity across dozens of organs.

The work, while still in animals, is among the most compelling demonstrations yet that aging in primates might be reversible.

The Science Behind the Breakthrough

At the heart of the study are mesenchymal progenitor cells (MPCs) – a type of stem-like cell found in bone marrow and connective tissues. These cells act as the body’s maintenance crew, capable of turning into bone, cartilage, fat, and muscle cells, while also secreting factors that help nearby tissues repair themselves.

But like all cells, MPCs age with us and eventually succumb to senescence  a state of permanent retirement. Senescent cells don’t divide anymore. Worse, they pump out inflammatory molecules, scar tissue signals, and other “toxic chatter” that accelerate aging in neighboring cells. In effect, senescent cells spread decline.

Upgrading the Repair System with FoxO3

To overcome this exhaustion, researchers turned to FoxO3, a protein known as a longevity gene regulator. In healthy young cells, FoxO3 acts like a switchboard operator, turning on DNA repair pathways, antioxidant defenses, and stress-resistance programs. In older cells, FoxO3 activity wanes – leaving them vulnerable to damage.

Hydra, a freshwater organism capable of regenerating indefinitely, rely heavily on FoxO to keep their stem cells active. Humans share this same protein, and genetic studies link variants of FOXO3 to exceptional longevity in people.

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Scientists make embryos from human skin DNA for first time

US scientists have, for the first time, made early-stage human embryos by manipulating DNA taken from people’s skin cells and then fertilising it with sperm.

The technique could overcome infertility due to old age or disease, by using almost any cell in the body as the starting point for life.

It could even allow same-sex couples to have a genetically related child.

The method requires significant refinement – which could take a decade – before a fertility clinic could even consider using it.

Experts said it was an impressive breakthrough, but there needed to be an open discussion with the public about what science was making possible.

Reproduction used to be a simple story of man’s sperm meets woman’s egg. They fuse to make an embryo, and nine months later a baby is born.

Now scientists are changing the rules. This latest experiment starts with human skin.

The Oregon Health and Science University research team’s technique takes the nucleus – which houses a copy of the entire genetic code needed to build the body – out of a skin cell.

This is then placed inside a donor egg that has been stripped of its genetic instructions.

So far, the technique is like the one used to create Dolly the Sheep – the world’s first cloned mammal – born back in 1996.

However, this egg is not ready to be fertilised by sperm as it already contains a full suite of chromosomes.

You inherit 23 of these bundles of DNA from each of your parents for a total of 46, which the egg already has.

So the next stage is to persuade the egg to discard half of its chromosomes in a process the researchers have termed “mitomeiosis” (the word is a fusion of mitosis and meiosis, the two ways cells divide).

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FDA Considering Independent Evaluation for DNA Contamination in COVID-19 Vaccines

The Food and Drug Administration is mulling over conducting its own evaluation of the levels of DNA in COVID-19 vaccines, an FDA official has disclosed.

“I’ll say that that is something that’s being discussed,” Dr. Tracy Hoeg, a senior adviser to the FDA’s commissioner, told members of the Centers for Disease Control and Prevention’s vaccine advisory panel on Sept. 19.

Before the panel’s members unanimously recommended during the meeting that the CDC roll back COVID-19 vaccine recommendations, a number expressed concerns about growing evidence of higher-than-allowed levels of DNA in the vaccines, the spreadofthevaccinebeyond the injection site, and the long-term persistence of messenger ribonucleic acid (mRNA)—a key part of the Pfizer-BioNTech and Moderna shots.

The CDC has described mRNA as the entity teaching cells how to make copies of the spike protein to enable protection when the real virus, with its own spike protein, attacks the body. “After the mRNA delivers the instructions, your cells break it down and get rid of it,” a CDC graphic states.

Retsef Levi, chair of the advisory panel’s COVID-19 immunization workgroup, showed the graphic during the meeting.

“We have a range of things on the mRNA platforms that really suggests that it doesn’t work as intended,” Levi said, citing issues such as the spread of spike protein and mRNA into various parts of the body and “DNA contamination.”

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Moderna’s COVID Shot Plasmid Contains Human Blood Gene Fragment Capable of Integrating Into DNA—Same System Dominating Post-Vaccine Injuries

Moderna’s COVID-19 vaccine plasmid contains a human α-globin DNA fragment regulating blood and cardiovascular biology, and because plasmids are integration-competent DNA molecules, this fragment is capable of inserting into the human genome—precisely as blood and cardiovascular injuries like myocarditis and pericarditis emerge as the dominant serious adverse events following Moderna vaccination.

In plain terms, Moderna’s shot carries a piece of human blood gene code that can lodge itself into patient DNA, raising the possibility that the very blueprint of the vaccine is fueling the same heart and blood injuries now seen at the top of its safety reports.

While most public discussion blames the spike protein or lipid nanoparticles for Moderna’s adverse events, the evidence here points to something no one is talking about—the plasmid blueprint itself may be driving the blood and heart injuries dominating the safety signal.

A September 2025 peer-reviewed paper in Molecular Therapy: Nucleic Acids confirms that Moderna’s mRNA-1273 (Spikevax) vaccine plasmid carries a 3’ untranslated region (UTR) from the human α-globin (HBA1) gene.

  • α-globin encodes part of hemoglobin, central to red blood cell stability and oxygen transport.
  • Its regulation is directly tied to blood and cardiovascular function—mutations cause α-thalassemia, anemia, and cardiac stress.
  • By design, Moderna’s blueprint hard-codes this human blood gene regulator into the plasmid template.

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Giant, flightless bird is next target for de-extinction company Colossal Biosciences


A species of huge, flightless bird that once inhabited New Zealand disappeared around 600 years ago, shortly after human settlers first arrived on the country’s two main islands. Now, a Texas-based biotech company says it has a plan to bring it back.

Genetic engineering startup Colossal Biosciences has added the South Island giant moa — a powerful, long-necked species that stood 10 feet (3 meters) tall and may have kicked in self-defense — to a fast-expanding list of animals it wants to resurrect by genetically modifying their closest living relatives.

The company stirred widespread excitement, as well as controversy, when it announced the birth of what it described as three dire wolf pups in April. Colossal scientists said they had resurrected the canine predator last seen 10,000 years ago by using ancient DNA, cloning and gene-editing technology to alter the genetic make-up of the gray wolf, in a process the company calls de-extinction. Similar efforts to bring back the woolly mammoth, the dodo and the thylacine, better known as the Tasmanian tiger, are also underway.

To restore the moa, Colossal Biosciences announced Tuesday it would collaborate with New Zealand’s Ngāi Tahu Research Centre, an institution based at the University of Canterbury in Christchurch, New Zealand, that was founded to support the Ngāi Tahu, the main Māori tribe of the southern region of New Zealand.

The project would initially involve recovering and analyzing ancient DNA from nine moa species to understand how the giant moa (Dinornis robustus) differed from living and extinct relatives in order to decode its unique genetic makeup, according to a company statement.

“There is so much knowledge that will be unlocked and shared on the journey to bring back the iconic moa,” Ben Lamm, CEO and co-founder of Colossal Biosciences, said in the statement. For example, the company said, researching the genomes of all moa species would be “valuable for informing conservation efforts and understanding the role of climate change and human activity in biodiversity loss.”

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Eight Healthy Babies Born via IVF using DNA from Three People

In the United Kingdom, medical professionals have successfully delivered eight babies using a pioneering fertility procedure that incorporates DNA from three individuals.

This method aims to safeguard children from inheriting severe mitochondrial disorders. The births represent a cautious advancement in assisted reproduction, prioritizing family health and stability.

The mothers involved carried mutations in their mitochondria, risking life-threatening conditions for their offspring. Mitochondria serve as cellular energy sources, essential for bodily functions. Without intervention, these defects could devastate future generations.

The United Kingdom amended its laws in 2015 to permit this technique, reflecting deliberate ethical review. In 2017, regulators issued the initial license to Newcastle University’s fertility clinic. This institution led the development over two decades.

Among the newborns are four boys and four boys, including identical twins, from seven women. All show no evidence of the anticipated mitochondrial ailments. One additional pregnancy continues under medical care.

Professor Doug Turnbull, a key researcher, described the results as reassuring for families and scientists alike. He highlighted the relief in achieving positive outcomes for patients.

Professor Mary Herbert, a senior team member, expressed fulfillment in seeing eight healthy infants. She noted the achievement rewards the extensive collaborative work.

Human genes primarily reside in the cell’s nucleus, totaling around 20,000. However, mitochondria add 37 genes of their own. Faulty mutations here can lead to profound cellular energy deficits.

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Ancient ‘female-centered’ society thrived 9,000 years ago in Çatalhöyük

Ancient DNA from Stone Age burials in Turkey has finally put to rest a decades-long debate about whether the 9,000-year-old proto-city of Çatalhöyük was a matriarchal society. The research finally confirms what experts have long suspected: Women and girls were key figures in this agricultural society.

“With Çatalhöyük, we now have the oldest genetically-inferred social organisation pattern in food-producing societies,” study co-author Mehmet Somel, an evolutionary geneticist at Middle East Technical University in Turkey, told Live Science in an email. “Which turns out to be female-centered.”

The new research was published Thursday (June 26) in the journal Science.

Located in south-central Turkey, Çatalhöyük was built around 7100 B.C. and was occupied for nearly 1,000 years. The vast settlement — spread over 32.5 acres (13.2 hectares) — is known for its houses that were entered from the roofs, burials beneath the house floors, and elaborate symbolism that included vivid murals and a diverse array of female figurines.

When archaeologist James Mellaart first excavated Çatalhöyük in the early 1960s, he interpreted the numerous female figurines as evidence of a matriarchal society that practiced “mother goddess” worship, perhaps as a way of ensuring a good harvest following a major economic transition from foraging to cereal-based agriculture.

In the 1990s, Stanford archaeologist Ian Hodder took over excavations at Çatalhöyük, and his research suggested instead that the society was largely egalitarian, without meaningful social or economic differences between men and women.

To further investigate the social organization at Çatalhöyük, in a new study, a team of researchers that included both Somel and Hodder analyzed the DNA of 131 skeletons dated to between 7100 and 5800 B.C. that were buried beneath house floors.

The researchers connected 109 people across 31 buildings and found that all first-degree relatives (parents, children and siblings) were buried together in the same building, while second-degree (uncles, aunts, nephews, nieces and grandparents) and third-degree relatives (such as first cousins and great grandparents) were often buried in nearby buildings. This suggests that nuclear or extended families had a role in structuring Çatalhöyük households, the researchers wrote in the study.

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