Tag: vaccines

SARS-CoV-2 Vaccination and the Multi-Hit Hypothesis of Oncogenesis

Cancer is a complex and dynamic disease. The “hallmarks of cancer” were proposed by Hanahan and Weinberg (2000) as a group of biological competencies that human cells attain as they progress from normalcy to neoplastic transformation. These competencies include self-sufficiency in proliferative signaling, insensitivity to growth-suppressive signals and immune surveillance, the ability to evade cell death, enabling replicative immortality, reprogramming energy metabolism, inducing angiogenesis, and activating tissue invasion and metastasis. Underlying these competencies are genome instability, which expedites their acquisition, and inflammation, which fosters their function(s). Additionally, cancer exhibits another dimension of complexity: a heterogeneous repertoire of infiltrating and resident host cells, secreted factors, and extracellular matrix, known as the tumor microenvironment, that through a dynamic and reciprocal relationship with cancer cells supports immortality, local invasion, and metastatic dissemination. This staggering intricacy calls for caution when advising all people with cancer (or a previous history of cancer) to receive the COVID-19 primary vaccine series plus additional booster doses. Moreover, because these patients were not included in the pivotal clinical trials, considerable uncertainty remains regarding vaccine efficacy, safety, and the risk of interactions with anticancer therapies, which could reduce the value and innocuity of either medical treatment.

After reviewing the available literature, we are particularly concerned that certain COVID-19 vaccines may generate a pro-tumorigenic milieu (i.e., a specific environment that could lead to neoplastic transformation) that predisposes some (stable) oncologic patients and survivors to cancer progression, recurrence, and/or metastasis. This hypothesis is based on biological plausibility and fulfillment of the multi-hit hypothesis of oncogenesis (i.e., induction of lymphopenia and inflammation, downregulation of angiotensin-converting enzyme 2 (ACE2) expression, activation of oncogenic cascades, sequestration of tumor suppressor proteins, dysregulation of the RNA-G quadruplex-protein binding system, alteration of type I interferon responses, unsilencing of retrotransposable elements, etc.) together with growing evidence and safety reports filed to Vaccine Adverse Effects Report System (VAERS) suggesting that some cancer patients experienced disease exacerbation or recurrence following COVID-19 vaccination. In light of the above and because some of these concerns (i.e., alteration of oncogenic pathways, promotion of inflammatory cascades, and dysregulation of the renin-angiotensin system) also apply to cancer patients infected with SARS-CoV-2, we encourage the scientific and medical community to urgently evaluate the impact of both COVID-19 and COVID-19 vaccination on cancer biology and tumor registries, adjusting public health recommendations accordingly.

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The Hidden Tragedy of Neurological Vaccine Injuries

From birth, we are taught that vaccines were one of the most remarkable discoveries in history, and were so safe and effective that many now unimaginable plagues vanished with few to no side effects occurring in the process. In truth, give or take, every part of that mythology is false, and remarkably similar vaccine disasters occur every few decades.

Much of this results from the fact that it is very difficult to produce safe vaccines due to both their mode of action and the methods used in their production. As such, the best “solution” which could be found to this problem was to insist in lockstep that vaccines were safe and erase any memory that vaccine disasters had in fact occurred, thereby making it possible to gaslight anyone who was severely injured by a vaccine and claim their injury was just anecdotal or a product of anti-vaccine hysteria.

For example, recently I discussed how vaccines cause autism, and focused on a central argument used to debunk the link between the two—that the only reason people believe vaccines cause autism is because a disgraced British doctor published a fraudulent 1998 study claiming they did and then made everyone start hallucinating that vaccine injuries were occurring.

This mythology however, ignores that brain injuries were a longstanding problem of vaccination. For example, a 1982 NBC news program revealed that many parents were having children develop “post-pertussis encephalopathy” after taking the DPT vaccine, that most doctors refused to report this.

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CDC’s New Vaccine Advisers Vow to Study Cumulative Effect of Childhood Vaccine Schedule

The CDC’s new advisory committee today announced plans to look at the cumulative effect of all vaccines given during childhood.

Martin Kulldorff, Ph.D., the committee’s new co-chair, said:

“The number of vaccines that our children and adolescents receive today exceeds what children in most other developed nations receive — and what most of us in this room received when we were children.

“In addition to studying and evaluating individual vaccines, it is important to evaluate the cumulative effect of the recommended vaccine schedule. This includes interaction effects between different vaccines, the total number of vaccines, cumulative amounts of vaccine ingredients, and relative timing of different vaccines.”

A new committee work group will look into these issues, Kulldorff said. The Centers for Disease Control and Prevention currently recommends at least 70 doses of 15 different vaccines for children and adolescents up to age 18.

Another new work group will look at vaccines that have not been subject to reviewed in more than seven years, he added. “This was supposed to be a regular practice of the ACIP, but it has not been done in a thorough and systematic way. We will change that.”

ACIP began its two-day meeting today despite a call from Sen. Bill Cassidy (R-La.) late Monday to delay the meeting until the committee “is fully staffed with more robust and balanced representation.”

On June 11, U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. named eight researchers and physicians to the Centers for Disease Control and Prevention’s (CDC) vaccine advisory panel, two days after removing all 17 ACIP sitting members.

However, according to The New York Times, one of the new members, Dr. Michael A. Ross, a physician licensed in Virginia and a former professor of obstetrics and gynecology, withdrew from the committee.

Kennedy reconstituted the committee to “avoid conflicts of interest,” citing past members’ financial ties to pharmaceutical companies, he said in a Wall Street Journal op-ed about the change.

According to Cassidy, although the new committee members “have scientific credentials, many do not have significant experience studying microbiology, epidemiology or immunology. In particular, some lack experience studying new technologies such as mRNA vaccines, and may even have a preconceived bias against them.”

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Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic

Abstract

Background

Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics have been observed, but limited data are available on the relationship between COVID-19 vaccination status and birth rates.

Objectives

Therefore, we used nationwide data from the Czech Republic to examine rates of successful conceptions (SCs), that is, conceptions leading to live births 9 months later, for women who were either vaccinated or unvaccinated against COVID-19 before SC.

Methods

Summary monthly COVID-19 vaccination and birth data for women in the Czech Republic aged 18–39 years were retrieved for the period from January 2021 to December 2023. The numbers of SCs per month per 1000 women were calculated for preconception-vaccinated or unvaccinated women, respectively, as well as the number of SCs per month per 1000 women for all women aged 18–39 years.

Results

During the study period, there were approximately 1,300,000 women aged 18–39 years in the Czech Republic, and the proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. Furthermore, SC rates for the vaccinated group were much lower than expected based on their proportion of the total population.

Conclusions

In the Czech Republic, SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility.

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17 Ways mRNA Shots May Be Fueling Cancer, Backed by Over 100 Studies

A comprehensive literature review by Mathilde Debord titled “COVID-19 mRNA vaccines can induce cancer in 17 distinct ways, according to over 100 studies” was just published in Le Point Critique.

Drawing from over 100 peer-reviewed studies, it outlines 17 distinct biological mechanisms by which the injections may initiate, accelerate, or reactivate malignant processes.

1. Genome Instability

mRNA may be reverse-transcribed and integrated into host DNA, triggering mutations that initiate cancer.

2. Immune Escape

The spike protein binds and inhibits tumor suppressor genes like p53 and BRCA1, shielding cancer cells from immune destruction.

3. Impaired DNA Repair Mechanism

The spike protein interferes with essential DNA repair enzymes, increasing the risk of unchecked mutations.

4. Chronic Inflammation

Lipid nanoparticles and spike protein cause long-lasting inflammation, a well-known driver of cancer.

5. Dysregulation of the Immune System

Suppression of T cells and type I interferon weakens cancer surveillance and promotes immune evasion.

6. RNA Disruption

Codon optimization disrupts microRNA networks, destabilizing cell growth regulation and apoptosis.

7. Activation of Oncogenic Pathways

The spike protein indirectly activates MAPK and PI3K/mTOR signaling, fueling tumor growth and metastasis.

8. Tumor Microenvironment Alteration

Lipid nanoparticles accumulate in tumors, enhancing permeability and potentially accelerating cancer spread.

9. Awakening Dormant Cancers

Post-vaccination inflammation and immune disruption may trigger recurrence in patients previously in remission.

10. Alteration of Immune Surveillance

Modified mRNA blocks toll-like receptors, making tumor cells “invisible” to the immune system.

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Bill Gates’ New $1.6 Billion Project to Vaccinate Children Worldwide

The Gates Foundation has announced a commitment of $1.6 billion over the next five years to support Gavi, the Vaccine Alliance’s worldwide crusade to inject children and “the world’s most vulnerable communities” with vaccines.

The move comes after a recent Gates Foundation–funded human trial in South Africa injected children with live tuberculosis-family bacteria, infecting 260 kids—while earlier Gates-backed gain-of-function research had already engineered tuberculosis strains to grow uncontrollably.

The press release announcing the new pledge doesn’t mention safety once.

“The foundation’s renewed support comes amid a global crisis. International development programs have been severely impacted by declining budgets and shifting political priorities.”

“The Gates Foundation today announced a commitment of US$1.6 billion over the next five years to support Gavi, the Vaccine Alliance—one of the most effective mechanisms for delivering lifesaving vaccines to children and preventing disease in the world’s most vulnerable communities,” the Gates Foundation press release reads.

The Foundation is justifying the massive financial commitment based on its claim that “child deaths will rise” if more kids aren’t injected with pharmaceutical drugs.

This is despite CDC’s VAERS system showing 2,673,347 adverse events (injuries, hospitalizations, deaths) linked to vaccines since 1990.

A Harvard-HHS report found that VAERS captures fewer than 1% of actual adverse events, meaning the number could be closer to 200 million.

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RFK Jr. Clashes with Democrat in House Hearing over Vaccines: ‘You’ve Accepted $2 Million from Pharma’

Secretary of Health and Human Services Robert F. Kennedy Jr. clashed with Rep. Frank Pallone (D-NJ) during a fiery House Energy and Commerce Committee hearing Tuesday, claiming the Democrat was abandoning vaccine-injured Americans after accepting millions in donations from the pharmaceutical industry.

Kennedy was testifying on the Trump administration’s fiscal year 2026 budget request for the Department of Health and Human Services when Pallone launched into a blistering attack. “Secretary Kennedy, quite frankly, I think you’re trying to defend the indefensible. There’s no way that this budget or the actions you have taken thus far as secretary are going to make this country healthier,” he said. Pallone went on to accuse the Secretary of pushing anti-science views, promoting conspiracy theories, and endangering lives with his vaccine policies. “I just really think that people are going to die as a result of your actions and congressional Republicans’ actions,” he warned.

Pallone also raised concerns about the lack of communication between HHS and Congress. He pressed further, demanding to know why Kennedy had not opened public comments on vaccine-related decisions. “You say you want transparency, but there’s been no public process for any of this. Why?” he asked.

Kennedy replied, “We have a public process for regulating vaccines. It’s called the ACIP committee, and it’s a public meeting that we —”

Pallone cut in, “You fired the committee.”

Kennedy responded, “I fired people who had conflicts with the pharmaceutical industry. That committee has been a template for medical malpractice for years.”

As his time for questioning drew to a close, Pallone concluded, “The bottom line is here we have no transparency, we have no response. You feel no responsibility to Congress whatsoever, and you just continue this ideology that’s anti-science, anti-vaccine. That’s all I see. I see nothing else. And I don’t think I’m ever going to get a response.”

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FDA, CDC advisers say lost pregnancies higher than expected following early mRNA vaccination

President Trump’s second-term agenda has been careful not to cast doubt on his signature first-term achievement, the development of COVID-19 vaccines through Operation Warp Speed, which congressional Republicans continue to laud and even claim was sabotaged by Pfizer to deny Trump a consecutive term despite his base souring on the therapeutics.

A new preprint study on mRNA COVID vaccines in early pregnancy, coauthored by top advisers to Trump’s Food and Drug Administration and Centers for Disease Control and Prevention, may fuel the splintering of the Make America Healthy Again movement as the jabs’ opponents ramp up pressure on Health and Human Services Secretary Robert F. Kennedy Jr. to ban them.

Not yet peer-reviewed, the study analyzed hundreds of thousands of Israeli medical records on pregnant women in the three years before and after SARS-CoV-2 emerged in China, finding 43% more “observed-to-expected” fetal losses per 100 pregnancies — 13 instead of nine — when the first mRNA dose is taken between 8-13 weeks’ pregnancy.

Pregnant women who took a booster between 8-13 weeks lost an additional two pregnancies per 100, a “potential dose-response relationship,” the study said.

By using pregnant women who got flu vaccines between 8-27 weeks and women who received either vaccine before their pregnancy as “comparative controls,” the authors said they were able to show the association is unique to COVID vaccines. 

The former had a “consistently lower-than-expected observed number of fetal losses, likely the result of healthy vaccinee bias” – in which people with overall better health tend to have higher vaccination rates – while the latter had “according-to-expected or lower-than-expected numbers of fetal losses,” the study found.

It said “almost all” mRNA doses were made by Pfizer, whose own 2021 report to the FDA – which the agency hid for 16 months until a court made it public – shows 44% of women in Pfizer’s clinical trial lost their pregnancies.

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Activists Hopeful as CDC Advisers Vote on Thimerosal Removal

Advisers to the Centers for Disease Control and Prevention are set to vote on June 26 on whether to recommend that the CDC act to remove thimerosal from influenza vaccines, raising hopes from people who have advocated eliminating the preservative.

“We are hopeful that the consideration of thimerosal will spark a thorough discussion that it deserves, hopefully leading to its removal from all vaccines,” Brian Hooker, chief scientific officer for Children’s Health Defense, told The Epoch Times via email.

Thimerosal, approximately 50 percent mercury by weight, has been used in vaccines since the 1930s.

Concerns that the preservative could cause health problems resulted in a congressionally mandated 1999 review that concluded that some infants might be exposed to levels of mercury above recommended guidelines from the Environmental Protection Agency.

A House of Representatives subcommittee in 2003, following the review, said that “mercury is hazardous to humans” and that it “should be minimized or eliminated entirely” from medicinal products.

The Food and Drug Administration, which has worked with companies to reduce or eliminate thimerosal from vaccines, says that the use of thimerosal has subsequently declined, but it maintains that studies “support the safety of thimerosal-containing vaccines.”

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Did Head of CDC Vaccine Safety Office Delete COVID Vaccine Injury Records?

A key official at the Centers for Disease Control and Prevention (CDC) responsible for monitoring vaccine safety and reports of vaccine injuries may have mishandled or deleted official records subpoenaed by Congress, Sen. Ron Johnson (R-Wis.) alleged earlier this week. The New York Post first reported the story on Thursday.

Dr. Tom Shimabukuro, director of the CDC Immunization Safety Office, maintained the records in question. Shimabukuro previously authored a key paper and participated in public messaging claiming the COVID-19 vaccines were safe and effective for pregnant women.

Johnson, chairman of the U.S. Senate Permanent Subcommittee on Investigations, requested the records in a subpoena sent in January to the U.S. Department of Health and Human Services (HHS). The subpoena pertained to an investigation into internal COVID-19 vaccine safety communications.

According to the New York Post, the subpoena led HHS to discover “potential discrepancies” in the emails maintained by Shimabukuro.

“HHS officials recently informed me that Dr. Shimabukuro’s records remain lost and, potentially, removed from HHS’s email system altogether,” Johnson wrote in a letter he sent earlier this week to U.S. Attorney General Pam Bondi, FBI Director Kash Patel and HHS Principal Deputy Inspector General Juliet Hodgkins.

Johnson called Shimabukuro’s possible mishandling of his official records “highly concerning.”

Journalist Paul D. Thacker, a former U.S. Senate investigator, said, “Every American should be concerned about government scientists deleting or hiding federal information to shape a political agenda. That information belongs to the taxpayers.”

Nebraska chiropractor Ben Tapper, whose questioning of the COVID-19 vaccines led the Center for Countering Digital Hate to add him in 2021 to its “Disinformation Dozen” list of the “leading online anti-vaxxers,” said he was “not surprised” by Johnson’s allegations.

“For years, I’ve seen patterns like this before regarding vaccine safety data. The public health establishment often prioritizes profits over people and continuously seems to protect the lies over the truth. The idea that critical records might vanish — whether through negligence or intent — fits a familiar playbook,” Tapper said.

California attorney Rick Jaffe said Johnson’s allegations are “troubling, but not surprising, given longstanding concerns about transparency at the CDC.”

In response to a Freedom of Information Act (FOIA) request last year, the CDC told Children’s Health Defense the agency has no records of certain internal email communications relating to the agency’s follow-up investigation of safety signals associated with COVID-19 vaccines.

HHS, CDC and Johnson’s office did not respond to requests for comment.

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