Trial shows promise for treating anxiety with LSD

At Dr. David Feifel’s Kadima Neuropsychiatry Institute clinic in La Jolla, patients come in with depression, anxiety, PTSD, OCD and eating disorders.

But what sets this office apart is how these diagnoses are treated.

“I just felt that I wanted to create a center that focused on these advanced treatments that have expertise in these treatments and that also would be involved in developing the next generation of treatments,” Dr. Feifel said.

He opened his clinic in 2017 and is excited for this new era in psychedelic research.

“We’re picking up where we left off 30-40 years ago, and they are just looking very, very promising,” Dr. Feifel said.

One of the fastest-growing conditions his clinic sees is generalized anxiety disorder, or GAD.

“We see it especially growing among the youth and young females especially,” Dr. Feifel said.

One of those patients is Lucas Hoffman, who’s battled GAD for years, trying treatment after treatment for several years, with no major benefits.

As part of Dr. Feifel’s clinic, Hoffman joined a clinical trial for a new investigational drug called MM-120, a pharmaceutically optimized version of LSD.

“I came in that morning, I was a little late for the dosing session because I was dragging at home,” Hoffman said. “I was pretty, pretty nervous,”

In a controlled environment, patients receive a single monitored dose.

“I really personally, and this cannot represent the expectation for any of you on the trial, I really did, feel a sense of freedom,” Hoffman said. “I felt a breakthrough of some of the anxiety that was holding on so tightly to me.”

Early results are encouraging.

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Michigan Lawmakers Consider Bills To Change Legal Marijuana Possession Limits And Alter Industry Disciplinary Rules

Four marijuana-related bills were up for consideration before a House panel on Thursday, with one aiming to upend rules on the legal amount of regulated marijuana a person is allowed to possess, both in plant and concentrate form.

Members of the House Regulatory Reform Committee discussed but did not amend or advance House Bill House 5104, Bill 5105, House Bill 5106 and House Bill 5107.

Derek Sova, a policy and legislative assistant for the Cannabis Regulatory Agency, told the committee previously that Michigan’s legal marijuana industry faced several challenges, and that two of those big hurdles were large illicit grow operations and the agency’s inability to go after bad actors because their licenses had expired.

The series of bills before the committee would address those concerns.

House Bill 5105 and House Bill 5107 are sponsored by state Reps. Pauline Wendzel (R-Watervliet) and Mike Hoadley (R-Au Gres), respectively. The bills would in tandem create new penalties for cultivating, delivering and processing black market marijuana, but also change the amount of marijuana a person is legally allowed to possess in plant and concentrate form.

The bills are tie-barred together, meaning both would have to jointly clear the Legislature and be signed by the governor to become law.

Under Wendzel’s bill, a person would be guilty of a misdemeanor if they possess between 10 and 25 kilograms, or between 50 and 100 plants, or between one and 2.5 kilograms of marijuana concentrate. The penalty would change to up to one year in jail or a $20,000 fine, or both.

Keeping between 25 and 125 kilograms, or between 100 and 500 plants, or between 2.5 and 12.5 kilograms of marijuana concentrate would become a felony punishable by two years in prison or a $500,000 fine, or both.

It would also be a felony offense to:

  • Keep between 125 and 250 kilograms, or between 500 and 1,000 plants, or between 12.5 and 25 kilograms. That could net a person four years in prison or a $2 million fine or both; and
  • Keep 250 kilograms or more, or 1,000 plants or more, or 25 kilograms or more of marijuana concentrate. The punishment there would be up to 10 years in prison or a $10 million fine, or both.

Sponsored by state Rep. Kristian Grant (D-Grand Rapids), House Bill 5104 would allow the Cannabis Regulatory Agency to sanction a person even if they are no longer a licensee or if they are no longer operating a marijuana facility.

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FBI announces massive indictment against 33 alleged members of drug trafficking organization

The FBI and Justice Department on Friday announced a massive indictment against over two dozen alleged members of the Weymouth Street Drug Trafficking Organization in Kensington, Pennsylvania.

The indictment accused 33 alleged gang members of conspiracy to distribute controlled substances and dozens of related offenses. The organization was known for peddling and distributing fentanyl, heroin, and cocaine.

FBI Director Kash Patel said the operation should serve as an example of law enforcement reclaiming violent corridors from gangs, and touted the years of collaboration between the bureau, Philadelphia Police Department and the U.S. Attorney’s Office, Fox News reported.

“This takedown is how you safeguard American cities from coast to coast,” Patel said. “We have permanently removed a drug trafficking organization off the streets of Philadelphia.” 

The crew allegedly used violence to enforce its territory with shootings, murder and assaults. Despite the alleged use of violence, no substantial murder or shooting charges have been filed so far.

Prosecutors said the organization was allegedly led by 45-year-old Jose Antonio Morales Nieves, of Luquillo, Puerto Rico, known as ‘Flaco,’ Ramon Roman-Montanez, 40, of Philadelphia, known as ‘Viejo,’ and 33-year-old Nancy Rios-Valentin of Philadelphia.

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A Trumpian Headache

President Donald Trump’s use of the U.S. military to kill persons on speed boats in international waters, or in territorial waters claimed by other sovereign nations – all 1,500 miles from the U.S. – has posed grave issues of due process. The Constitution’s guarantee of due process requires it for every person, not just Americans. The operative language of the Fifth Amendment is that “No person… shall be deprived of life, liberty, or property without due process of law.”

The Trump administration has claimed that it can kill whomever it designates as an unlawful enemy combatant – it prefers the political phrase “narco-terrorist” – and the due process it provides is the intelligence gathered by American spies and the White House analysis of that intelligence. This secret analysis, the government’s argument goes, satisfies the president that the folks he has ordered killed are engaging in serious and harmful criminal behavior, and somehow is a lawful and constitutional substitute for the jury trial and its attendant procedural protections that the Constitution commands.

To be fair, I am offering an educated guess as to the administration’s argument. The reason we don’t know the argument precisely is that the Department of Justice calls it classified. This is, of course, a non sequitur. How could a legal argument possibly be secret in light of well-settled First Amendment jurisprudence? It can’t. The Supreme Court has ruled consistently that there are no secret laws or secret rationales for employing the laws. Moreover, it has ruled that the First Amendment assures a public window on government behavior whenever it seeks to take life, liberty or property.

The last time we went through efforts to obtain the government’s legal argument for presidential targeted killing was during the Obama administration. When President Barack Obama ordered the CIA to kill Anwar al-Awlaki and his son – both natural born American citizens – it, too, claimed a secret legal rationale. Yet some brave soul who had access to that rationale leaked it to the press. The rationale likened killing al-Awlaki and his 16-year-old son to police shooting at fleeing bank robbers who are shooting at the police.

The Obama justification was absurd, as al-Awlaki was not engaged in any violent acts. He had been followed by 12 intelligence agents during his final 48 hours of life. Those agents couldn’t legally arrest him, because he hadn’t been charged with a crime, but in the Obama logic, they could legally kill him.

When those of us who monitor the government’s infidelity to the Constitution publicly pointed out the flaws in the Obama argument, it reverted to the argument that I suspect the current administration is secretly using. Namely, that its secret internal deliberations are a constitutionally adequate substitution for traditional due process.

It gets worse.

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The Sordid History Of US “Aid” To Colombia

President Donald Trump is rattling his saber against Colombian President Gustavo Petro to punish him for accusing the US government of murdering Venezuelan fishermen. Trump has boasted of the killings by the US military but claims all the targets were drug smugglers. He has threatened to suspend all US government handouts for the Colombian government. Trump warned Petro that he “better close up” cocaine production “or the United States will close them up for him, and it won’t be done nicely.”

Tapping his own psychiatric expertise, Trump proclaimed that Colombia has “the worst president they’ve ever had – a lunatic with serious mental problems.” Is anyone in the Trump White House aware of the long history of U.S. failure in that part of the world? In 1989, President George H.W. Bush warned Colombian drug dealers that they were “no match for an angry America.” But Colombia remains the world’s largest cocaine producer despite billions of dollars of US government anti-drug aid to the Colombian government.

The Bill Clinton administration made Colombia its top target in its international war on drugs. Clinton drug warriors deluged the Colombian government with U.S. tax dollars as they literally deluged Colombia with toxic sprayThe New York Times reported that U.S.-financed planes repeatedly sprayed pesticides onto schoolchildren, making many of them ill. Colombian environmental minister Juan Mayr publicly declared last year that the crop spraying program has been a failure and warned, “We can’t permanently fumigate the country.”

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China Is Smuggling Fentanyl to US Through Venezuela, Trump Says

U.S. President Donald Trump confirmed on Oct. 23 that China is smuggling fentanyl into the United States through Venezuela to bypass U.S. and Mexican controls.

“They are doing that, yes, but they are paying right now 20 percent tariff because of fentanyl,” Trump told reporters.

Trump said it is one of the issues he will bring up with Chinese Communist Party (CCP) leader Xi Jinping at their bilateral meeting next week.

“The first question I’m going to be asking them about is fentanyl,” he said.

Trump said that with the tariffs on China, which will rise by an additional 100 percent on Nov. 1 if no deal is made, the fentanyl operation will no longer be sustainable for China.

“They make $100 million sell[ing] fentanyl into our country … they lose $100 billion with the 20 percent tariff. So it’s not a good business proposition,” Trump said. “They pay a very big penalty for doing that, and I don’t think they want to be doing it.”

Trump’s meeting with Xi will come at the tail end of his Asia tour, for which he is departing on Oct. 24.

Earlier this year, FBI Director Kash Patel told lawmakers he had spoken to counternarcotics authorities in China and urged them to restrict exports of more fentanyl precursor chemicals.

The Chinese Ministry of Public Security in August added seven chemicals to an export control list, three of them central to producing fentanyl. The restrictions went into effect Sept. 1.

The United States has determined that China is the main supplier of the deadly illicit drug in the United States, and Trump in an executive order on Feb. 1 imposed initial tariffs on China for its “central role” in the fentanyl crisis.

In the order, Trump noted that despite a long history of discussions over the years, Chinese regime officials “have failed to follow through with the decisive actions needed to stem the flow of precursor chemicals.”

According to the order, in addition to subsidizing and incentivizing chemical companies to create and export fentanyl precursors, the regime has also provided “support and safe haven” for transnational criminal organizations that launder the related profits.

“The CCP does not lack the capacity to severely blunt the global illicit opioid epidemic; it simply is unwilling to do so,” the order reads.

In recent weeks, Trump has authorized nine strikes on vessels suspected of trafficking drugs.

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Ohio Health Agency Grants $400,000 To Fund Psychedelics Education And Training For First Responders, Doctors And More

An Ohio health agency is providing a state university with a $400,000 grant to educate first responders, law enforcement, emergency departments and behavioral specialists about how to deal with potential adverse psychedelic experiences as more people use the substances for medical or recreational purposes.

Amid the expanding psychedelics reform movement, there’s been increased attention to the possible health benefits of substances like psilocybin and ibogaine. But only a handful of states allow for the regulated use of certain psychedelics, typically in medically supervised settings.

Ohio is not among those states yet, but Ohio State University (OSU) is now launching its Psychedelic Emergency, Acute, and Continuing Care Education (PEACE) initiative, with nearly half a million dollars of funding from the state Department of Behavioral Health’s (DBH) SOAR Innovation grant program.

“People have started to learn about the benefits of psychedelics while, at the same time, the federal government categorizes these as controlled substances,” Stacey Armstrong, associate director of the OSU’s Center for Psychedelic Drug Research and Education (CPDRE), said in a press release last week.

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Trump Suggests US Strikes on Alleged Drug Shipments on ‘Land’ Are Coming Soon

President Trump on Wednesday suggested that US strikes on alleged drug shipments “on land” could be coming soon amid the US bombing campaign targeting boats in Latin America.

Trump has made similar comments before, and according to multiple media reports, the US is preparing to bomb Venezuela with the goal of ousting Venezuelan President Nicolas Maduro and is using cracking down on drug trafficking as a pretext.

The president claimed to reporters at the White House that he had “legal authority” to launch the strikes, but Congress hasn’t authorized the bombing campaign, which the Constitution requires for launching a war. Trump said he may notify Congress of the plans to launch strikes on land targets, but didn’t say he would seek authorization.

“We will hit them very hard when they come in by land. And they haven’t experienced that yet, but now we’re totally prepared to do that. We’ll probably go back to Congress and explain exactly what we’re doing when [they] come to the land,” the president said.

The president previously told Congress that he believes the US is now in an “armed conflict” with drug cartels. Trump has framed the airstrikes as self-defense, pointing to the large numbers of drug overdoses in the US, but they are primarily caused by fentanyl and other synthetic opioids, which don’t come from Venezuela, something Sen. Rand Paul (R-KY), who has been very critical of the campaign, has pointed out.

“There is no fentanyl made in Venezuela. Not just a little bit, there’s none being made. These are outboard boats that, in order for them to get to Miami, would have to stop and refuel 20 times,” Paul told British journalist Piers Morgan this week.

“It’s all likely going to Trinidad and Tobago. There are a lot of reasons to be worried about this. Number one is the broader principle of when can you kill people indiscriminately when there’s war. That’s why when we declare war is supposed to be done by Congress. It’s not supposed to be done willy nilly. When there’s war you just kill people in the war zone, there are rules of engagement,” Paul added.

Since September 2, the US has bombed at least seven boats in the Caribbean and one in the eastern Pacific near Colombia, extrajudicially executing 34 people at sea, according to numbers released by the Trump administration, without providing evidence to back up its claims about the targets. Sources told The Washington Post on Wednesday that any US airstrikes in Venezuela would likely first target alleged trafficker encampments or clandestine airstrips, but regime change remains the ultimate goal.

“There really is no turning back unless Maduro is essentially not in power,” a person familiar with the administration’s deliberations told the Post.

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US military conducts ninth lethal strike on drug smuggling vessels in Eastern Pacific

Three narcoterrorists were killed in what is believed to be the ninth deadly attack on vessels attempting to smuggle illegal drugs into the U.S. Secretary of War Pete Hegseth announced the strike on social media Wednesday evening.

Hegseth’s post included a video that showed a small boat moving along the water. Several seconds into the video, the boat explodes and is seen floating motionless in flames.

The latest strike took place in the Eastern Pacific, marking the second strike against a vessel in the Eastern Pacific within a day. The previous seven took place in the Caribbean.

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Ohio House Passes Bill To Remove Voter-Approved Marijuana Legalization Protections And Restrict Hemp Market

The Ohio House of Representatives has passed a bill that would make significant changes to the state’s voter-approved marijuana legalization law by removing several protections for consumers while also adding a series of new restrictions on hemp products that are intended to align the two sectors of the cannabis industry.

After moving through several House committees this week, with substantive amendments, the full chamber approved the legislation from Sen. Stephen Huffman (R) in a 87-8 vote on Wednesday.

While the measure previously passed the Senate in earlier form it will need to return to that chamber for concurrence, or go to a bicameral conference committee, before potentially heading to the governor’s desk.

Certain controversial provisions of the bill as passed by the Senate were scaled back by the House, but advocates are concerned that it would still make major changes to the marijuana law voters approved in 2023.

Rep. Brian Stewart (R), who has shepherded the legislation through the House, argued ahead of the floor vote that the legislation effectively reaches a “carefully crafted compromise” between lawmakers with differing perspectives on cannabis issues.

“This bill has been very difficult to wrangle, but most of our substantive bills usually are. Rather than being some kind of mushy muddle of weak sauce tie-breakers, this bill does what we all claim that we wanted to come to Columbus to do,” he said. “It tackles the issue head-on. It makes tough decisions. It respects and implements the feedback from residents and advocates across the affected industries. This bill wisely balances between Ohioans’ individual liberties, their safety, the financial wellbeing of our local communities and the need to protect the health and safety of Ohio’s children.”

Rep. Jamie Callender (R), who sponsored marijuana legalization legislation ahead of voters’ approval of the reform at the ballot, said the bill is “not perfect” but argued that lawmakers “have to act” to address intoxicating hemp and other pending issues.

“This is the revised code we’re writing,” he said. “I anticipate there will be numerous other bills on these topics in the near- and long-term future, as there should be… I’ll keep working with everyone to make it better.”

While its supporters have described it as a less heavy-handed approach compared to the original Senate bill, the measure would make substantive changes to the existing legalization law—with several provisions that advocates say directly contradict the will of voters and represent overreach on the part of lawmakers.

For example, the proposal would eliminate language in current statute providing anti-discrimination protections for people who lawfully use cannabis. That includes protections meant to prevent adverse actions in the context of child custody rights, the ability to qualify for organ transplants and professional licensing.

It would also recriminalize possessing marijuana from any source that isn’t a state-licensed dispensary in Ohio or from a legal homegrow. As such, people could be charged with a crime for carrying cannabis they bought at a legal retailer in neighboring Michigan.

Additionally, it would ban smoking cannabis at outdoor public locations such as bar patios—and it would allow landlords to prohibit vaping marijuana at rented homes. Violating that latter policy, even if it involves vaping in a person’s own backyard at a rental home, would constitute a misdemeanor offense.

Karen O’Keefe, director of states policies at the Marijuana Policy Project (MPP), said in a letter to House lawmakers on Wednesday that SB 56 as currently drafted “eliminates essential protections from the voter-enacted law and recriminalizes innocuous conduct that voters legalized.”

“Please reject this erosion of freedoms enacted by voters,” she said.

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