Legalizing Medical Marijuana Leads To ‘Significant Decrease’ In Opioid Companies’ Payments To Pain Doctors, Study Shows

Legalizing medical cannabis appears to significantly lessen monetary payments from opioid manufacturers to doctors who specialize in pain, according to recently published research, with authors finding “evidence that this decrease is due to medical marijuana becoming available as a substitute” for prescription painkillers.

“We find MML [medical marijuana legalization] leads opioid manufacturers to decrease direct payments to physicians prescribing opioids,” wrote authors, from the University of Florida, University of Southern California and the State University of New York (SUNY) at Buffalo. “Our analyses suggest this shift is due to increased adoption of marijuana for pain management, indicating that opioid manufacturers perceive marijuana as a superior substitute and respond by reducing these payments.”

The study was published late last year in the Journal of the American Statistical Association and was partially funded through a grant from the National Science Foundation. It looked at various financial incentives that opioid drugmakers provide to prescribing doctors—such as consulting fees and travel to conferences—and used a novel method of analysis meant to estimate causal effects from observational data.

“Our analysis finds a significant decrease in direct payments from opioid manufacturers to pain medication physicians as an effect of MML passage,” the report says.

Wreetabrata Kar, an assistant professor of marketing in the SUNY Buffalo’s school of management, co-authored the new study.

“Our findings indicate that medical marijuana is increasingly viewed as a substitute for opioids in chronic pain treatment, with the potential to transform pain management practices and help mitigate the opioid crisis that has profoundly affected communities across the U.S.,” the researcher explained in a press release. “The availability of new pain management options can change the financial dynamics between drug companies and health care providers.”

The team’s analysis found that decreases in direct payments from opioid makers to physicians was higher among physicians “practicing in localities with higher white populations, lower affluence, and a larger proportion of working-age residents.”

“Lower income regions tend to have higher rates of chronic pain and opioid misuse, making them key areas for potential substitution with medical marijuana,” Kar said. “Black patients are also less likely to be prescribed opioids for pain, and younger populations may be more open to alternative treatments, which could explain the different impacts of marijuana legalization in these communities.”

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Biden Dodges Question About Releasing Marijuana Prisoners Before Leaving Office, As He Previously Promised He Would Do

President Joe Biden declined to respond to a question over the weekend about whether he plans to fulfill his campaign promise to release people still imprisoned for marijuana before his term ends later this month.

Following a ceremony where Biden awarded various figures with Presidential Medals of Freedom recognizing their contributions to national interests on Saturday, New York Post reporter Steven Nelson called out to the president, asking “will you honor your campaign pledge to release all marijuana inmates?”

Biden didn’t acknowledge the question, exiting the event without talking to attending press.

With just two weeks until President-elect Donald Trump assumes the office again following his November election victory, there’s been added pressure on Biden to make good on his promise and take executive action to ensure nobody is incarcerated over non-violent federal cannabis convictions.

But while the White House has indicated that there are still clemency options being considered, there’s been no additional confirmation that Biden plans to go beyond the pardons and commutations he’s already issued for simple marijuana possession offenses.

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Study: Patients Less Likely To Have Suicidal Thoughts Following Medical Cannabis Use

Patients prescribed cannabis-based medicinal products (CBMPs) report decreases in the prevalence and intensity of suicidal thoughts, according to observational data published in the journal Archives of Suicide Research.

British investigators assessed rates of suicidal ideation in a cohort of patients authorized to use botanical cannabis or oil extracts. (British physicians are permitted to prescribe cannabis-based medicinal products to patients who are unresponsive to conventional medications.)

Researchers reported, “Three months after commencing treatment, there was a reduction in both the percentage of the sample reporting suicidal ideation and the mean severity of suicidal ideation. … Twelve-month follow-up indicated a substantial reduction in depressed mood with this reduction being more pronounced in those reporting SI [suicidal ideation at baseline.]”

The study’s authors concluded: “To the best of our knowledge, this is the first observational study of CBMPs to report on rates of suicidal ideation. … The current findings suggest CBMPs may be effective in reducing suicidal ideation, as well as other facets of health and well-being … while also suggesting that the presence of suicidal ideation should not be used as a reason to exclude an individual from CBMPs treatment.”

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Federal Judge In Texas Rules That Ban On Gun Ownership By Marijuana User Is Unconstitutional As Applied

A federal judge in El Paso has ruled that the U.S. government’s ongoing ban on gun ownership by habitual marijuana users is unconstitutional in the case of a defendant who earlier pleaded guilty to the criminal charge. The court this week allowed the man to withdraw the plea and ordered that the indictment against him be dismissed.

The new ruling stops short of declaring that the law against firearm ownership by cannabis users—18 U.S.C. § 922(g)(3)—is itself unconstitutional. As applied to the defendant in the case, however, it says that government lawyers failed to demonstrate that the restriction aligns with the nation’s history of regulating gun ownership, noting that that they did “nothing in the way of proving that Defendant was intoxicated by marijuana at the time of this incident.”

David Briones, a senior U.S. District Court judge for the Western District of Texas, also acknowledged in the decision that the legal landscape around marijuana and the Second Amendment had evolved since the court first accepted the guilty plea. In the interim, the U.S. Court of Appeals for the Fifth Circuit, which includes Texas, ruled that while “some limits on a presently intoxicated person’s right to carry a weapon” may be constitutional, “disarming a sober person based on past substance usage” is not.

That case, U.S. v. Daniels, was set to be considered by the U.S. Supreme Court earlier this year but was among a number of firearms-related cases remanded back to lower courts following a separate Supreme Court decision about firearms and domestic violence.

“In the past two years alone,” Briones, a Clinton appointee, wrote in the new ruling, “the Fifth Circuit and the United States Supreme Court have heard and considered the following cases: DanielsRahimi, and Bruen. These cases have changed the law when it comes to the Second Amendment, and in the case of Daniels, have challenged the constitutionality of the very statute under which Defendant is charged.”

In the case, the El Paso Police Department responded to a 2021 call at the defendant’s home, entered the house and found two bags of marijuana. A search also found multiple guns inside the home. The defendant allegedly told officers that he’d used marijuana regularly for years and understood it was illegal to have both a medical marijuana card and a gun.

After the guilty plea, the defendant appealed his case to the Fifth Circuit, which later remanded it back to the district court in light of the recent precedent-setting opinions.

“This court now has a fuller picture of the Second Amendment jurisprudence as it stands today,” the order says, “and has reconsidered its position.”

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Homeland Security Agents Charged With Selling Illegal Drugs Seized As Evidence

A second Homeland Security agent has been charged with selling illegal drugs, taken from seized evidence, for hundreds of thousands of dollars through a confidential informant.

Nicholas Kindle, a special agent in Utah tasked with investigating illegal narcotics trafficking, was arrested three weeks after his alleged co-conspirator, special agent David Cole. Both men face felony drug distribution conspiracy charges. Kindle faces an additional charge of conspiracy to convert U.S. government property for profit.

Kindle was formally charged in an information document filed by the U.S. Attorney’s Office, which does not require grand jury approval to initiate criminal proceedings. Court records indicate that he has not yet been assigned an attorney.

A magistrate judge on Jan. 3 set Kindle’s initial court appearance for Jan. 21 in Salt Lake City. If convicted, he faces a maximum penalty of 25 years in prison.

Cole was indicted by a grand jury on Dec. 18 and has pleaded not guilty to his drug distribution conspiracy charge. He is due to stand trial the week of Feb. 24 and faces a maximum of 20 years if convicted.

His attorney, Alexander Ramos, previously said that he was still trying to gather information about the case.

The pair’s Homeland Security credentials have been suspended following the indictments but they have not been terminated, according to court documents.

Synthetic bath salts, also known as Alpha-PHP, are controlled substances with effects comparable to methamphetamine and cocaine. Abuse of the drug can result in adverse effects, including vomiting, paranoia, hypertension, seizures, or even death, according to U.S. authorities.

Federal prosecutors stated that Cole and Kindle began acquiring the drugs from HSI evidence in 2021 and sold them to a confidential informant from 2022 to 2024.

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California Law Allowing Marijuana Cafes Takes Effect, With First Shops Already Expanding Services

A new California law allowing marijuana cafes officially took effect on Wednesday, authorizing local governments throughout the state to allow cannabis retailers to expand their services. And certain businesses are already leveraging the policy change.

Gov. Gavin Newsom (D) signed a bill from Assemblymember Matt Haney (D) into law in September. But while local governments can now start the process of allowing the Amsterdam-like cafes, it’s expected to take months before most jurisdictions have rules in place to conform to the state law.

Overall, the legislation will allow on-site marijuana consumption at licensed businesses to also offer non-cannabis food and non-alcoholic drinks and host live events such as concerts if they get permission from their local government.

Newsom vetoed a prior version of Haney’s cannabis cafe bill, saying that while he appreciated that the intent was to “provide cannabis retailers with increased business opportunities and an avenue to attract new customers,” he felt “concerned this bill could undermine California’s long-standing smoke-free workplace protections.”

To that end, the measure as enacted contains changes to create separation between public consumption spaces and back rooms of businesses where food is prepared or stored in order to better protect the health of workers in line with the governor’s concerns.

“I commend the author for incorporating additional safeguards, such as expressly protecting employees discretion to wear a mask for respiration, paid for at the expense of the employer, and requiring employees to receive additional guidance on the risks of secondhand cannabis smoke,” Newsom said in a signing statement in September.

The law makes explicitly clear that hemp-based food items or drinks are not considered “non-cannabis” products that could be sold at the cafes. It also says that non-cannabis items “shall be stored and displayed separately and distinctly from all cannabis and cannabis products present on the premises.”

The legislation will also allow live musical or other performances on the premises of a cannabis retailer in areas where on-site consumption is allowed.

There have been examples of California businesses that have found workarounds to permit on-site consumption while making food available to guests—but they’ve operated in a grey area, partnering with separately licensed restaurants that receive the profits.

The expectation is that—because those cities such as Los Angeles and San Francisco have already established certain regulations around consumption lounges, including ventilation requirements—they may be quicker to the draw to open up the additional services.

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DEA Fails To Release Updated Marijuana Arrest And Seizure Data, Drawing Criticism From Legalization Advocates

The Drug Enforcement Administration (DEA) is facing criticism after failing to release updated annual data on marijuana-related arrests and seizures as it has done in prior years.

The agency has been publishing and archiving the annual data from its Domestic Cannabis Eradication/Suppression Program (DCE/SP) for decades, and advocates say the information is critical, especially amid heightened consideration of federal marijuana policy reform.

The last time that DEA updated the cannabis arrest and seizures figures was May 2023.

That data showed that DEA seized more than 5.7 million marijuana plants in 2022, a demonstrable increase that bucked the trend that’s been observed over recent years as the state legalization movement has expanded. However, the agency made far fewer cannabis-related arrests that year.

“At a time when voters and their elected officials nationwide are re-evaluating state and federal marijuana policies, it is inconceivable that government agencies are unwilling to provide data on the estimated costs and scope of federal marijuana prohibition in America,” NORML Deputy Director Paul Armentano said in a blog post.

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Alabama Teen Killed During ‘No-Knock’ Drug Raid Had His Hands Raised, Lawsuit Says

A 16-year-old teenager had his hands raised when he was fatally shot by police during an unauthorized “no-knock” drug raid in Mobile, Alabama, last year, according to a civil rights lawsuit filed by his mother in federal court earlier this month.

The lawsuit against the City of Mobile and several anonymous Mobile police officers says Randall Adjessom came out of his room holding a gun when he heard someone break down the front door of the house where he lived with his mother, grandmother, aunt, and sisters. When he realized the intruders were police, he put his hands in the air and stepped back, but a Mobile Police Department (MPD) SWAT officer shot him four times.

“The complaint is replete with revelations from our pre-suit investigation,” civil rights attorneys representing Adjessom’s mother said in a press release accompanying the suit, “perhaps none more repulsive than the fact that MPD body-worn camera (BWC) video of the shooting clearly shows Randall begin to retreat after realizing the intruders into his family home were members of the police force when he was repeatedly shot and killed in cold blood.”

And after he was shot, the suit says, police left Adjessom to bleed out on the floor for four minutes before half-heartedly rendering medical aid.

If true, the lawsuit’s narrative—which purports to be backed by video evidence, internal affairs reviews, and a recent independent audit of the Mobile Police Department—is another tragic example of what happens when the drug war, unregulated SWAT teams, and the Second Amendment right to self-defense mix.

An MPD SWAT team executed a “no-knock” search warrant on November 18, 2023, as part of an investigation into Adjessom’s older adult brother for suspected marijuana sales. However, the lawsuit says Adjessom’s brother did not live at the residence the MPD acquired a search warrant for—only Adjessom, who was a minor, and several women in his family.  

The lawsuit says there were numerous problems with the raid besides the absence of its only articulated target: MPD officers intentionally didn’t evaluate the risk to civilians in its pre-warrant threat assessment or note the presence of civilians in its search warrant affidavit; didn’t obtain authorization for a nighttime raid from a judge, supervisor, or prosecutor; and failed to announce themselves until after they had breached the front door and entered the house. 

All those errors became a force that swept together—like a malevolent current—the MPD SWAT officers and Randall Adjessom, who came out of his bedroom and turned into the hallway holding a gun with a laser sight.

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CBD Is A ‘Promising Candidate’ For Treating Depression With ‘Few Side Effects,’ New Scientific Review Concludes

A new scientific review says there’s “accumulating” evidence that the marijuana component CBD “has antidepressant properties in humans and animals with few side effects” and may also aid in the reduction of inflammation and formation of new brain cells.

“In summary,” says the manuscript, newly accepted by the International Journal of Neuropsychopharmacology, “there is growing evidence that CBD may be a promising candidate for the treatment of depression.”

The review notes that while the anti-depressant effects of the cannabinoid have been previously reported, the mechanisms of action behind those effects are still poorly understood. “Therefore, this paper reviews the molecular targets, pharmacokinetics, and safety of CBD,” it says.

Authors from the departments of pharmacology at Nantong University, the First People’s Hospital of Yancheng and the Jiangyin Hospital of Traditional Chinese Medicine—all in Jiangsu, China—looked at recently published papers on experimental and clinical studies around CBD, concluding that effects seem to be linked to the cannabinoid’s role in reducing inflammation and enhancing neurogenesis.

As for the cannabinoids’ targets in the human body, authors wrote that “receptor mechanisms underlying CBD’s effects are very complex and involve in multiple receptors including CB1, CB2, GPR55, 5-HT1A, and PPARγ receptors.”

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Kentucky Residents Who Participate In State’s New Medical Marijuana Program Will Be Ineligible To Own Guns, Feds Warn

The federal Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF) is warning Kentucky residents that, if they choose to participate in the state’s medical marijuana program that’s set to launch imminently, they will be prohibited from buying or possessing firearms under federal law.

As Kentucky prepares to implement the medical cannabis law that Gov. Andy Beshear (D) signed last year, ATF has put residents on notice about the ongoing federal ban on gun ownership by people who use marijuana, regardless of individual state policies.

“You cannot possess firearms and ammunition and also be a user of marijuana,” ATF Special Agent AJ Gibes told WDRB this month, referring to a statute requiring gun purchasers to fill out a form that includes a question about whether they are an active marijuana consumer. If they check yes, they’re disqualified from owning the firearm.

Notably, Gibes said that while people who already own a gun aren’t “expected to” turn them over if they become state-legal cannabis patients, those who “wish to follow federal law and not be in violation of it” must “make the decision to divest themselves of those firearms.”

He added that ATF is “not actively seeking and working solely on investigations involving just the possession of firearms and marijuana because of our finite resources,” but that doesn’t change the law, and people will still be at risk of prosecution if they violate it.

ATF has also weighed in on other recent state cannabis policy developments.

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