Science recently uncovered these 5 fascinating facts about psychedelic substances

Scientists are interested in studying psychedelic substances because they have the potential to alter perception, cognition, and mood in ways that may be beneficial for treating a variety of mental health conditions. Some studies suggest that certain psychedelics may have therapeutic effects for conditions such as depression, anxiety, PTSD, addiction, and end-of-life anxiety.

The most commonly studied psychedelic drugs include psilocybin (the active compound found in “magic” mushrooms), lysergic acid diethylamide (LSD, also known simply as “acid”), dimethyltryptamine (or DMT, a naturally occurring psychedelic compound found in many plants and animals), and 3,4-methylenedioxymethamphetamine (known as MDMA or molly, a synthetic drug that produces both psychedelic and stimulant effects).

Below are five recent scientific discoveries related to psychedelic substances and their therapeutic potential.

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No drugs, no arrest – but bounty of cash for Mobile County Sheriff’s Office

You don’t have to be convicted of a crime for law enforcement to take your money or property. You don’t even need to be charged with one.

The procedure is known as civil asset forfeiture, which allows authorities to take cash and property that they can demonstrate was used in criminal activity or was illicit profits. The latest example in Mobile County occurred April 26 on Interstate 10 in Grand Bay when deputies pulled over an 18-wheeler and seized hundreds of thousands of dollars – despite making no arrests.

The practice has drawn fierce criticism in Alabama and across the country, which some going as far as labeling it “legalized theft.”

Mobile County Sheriff Paul Burch said his agency does not seize property without substantial evidence that it is connected to criminal enterprises.

“We don’t do so lightly,” he told FOX10 News. “And we work within the laws that are provided.”

During the stop last month, Burch said the deputy – assigned to a special operations unit and specially trained to spot possible drug couriers – noticed a discrepancy in the vehicle’s Department of Transportation number.

A search did not turn up any drugs, but a K-9 dog did alert on cash inside the truck – $323,000. The Sheriff’s Office seized it as suspected drug money. Now, it is on the driver to make a claim to try to get the money back.

“He has a right to do so,” Burch said. “And there’s a process for it. But we typically don’t make those type of seizures unless, you know, there’s a strong basis to do so.”

Burch said most people do not try to get it back because if it was ill-gotten, they do not want to draw attention from law enforcement. He would not go into all of the evidence in this case but said there a joint investigation with the Department of Homeland Security and the U.S. Border Patrol into drug smuggling.

Both federal and state law enforcement agencies routinely seize money and cash unconnected to criminal charges. FOX10 News recently highlighted a case in which Mobile police seized a vehicle – and already had sold it by the time a judge dismissed criminal charges against the driver. The civil case is set for a hearing soon in Mobile County Circuit Court.

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Arizona funds research into ‘magic mushrooms’ to treat PTSD and depression

Arizona is headed toward funding the first controlled clinical trials for whole mushroom psilocybin, or “magic mushrooms,” to treat an array of health issues, including post-traumatic stress disorder, anxiety and depression. 

The state’s nearly $18 billion 2024 budget contains a provision providing $5 million for whole mushroom psilocybin trials. The money is the culmination of the efforts of Dr. Sue Sisely, an internal medicine physician and principal investigator at Scottsdale Research Institute, which conducts nonprofit drug development research on psychedelics, along with a bipartisan group of state legislators. 

“We’re thrilled that the research on natural mushrooms will finally be able to move forward, so this is a big achievement that finally we’re going to get objective data,” Sisely told the Arizona Mirror. “This will give us reliable insight into how these mushrooms might help or harm people. We need to learn more about how this works.”

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Small amounts of ‘psychedelic’ mushrooms would be decriminalized in CT, under bill

At a time when more research is showing that the controlled ingestion of psilocybin mushrooms can help patients deal positively with depression, trauma and end-of-life issues, the state House of Representatives on Wednesday approved legislation that would decriminalize the possession of small amounts of the hallucinogenic fungi.

The bill, which opponents warned could lead to the eventual full legalization of the drug, passed 86-64 and next heads to the Senate. Thirteen Democrats voted against the bill and two Republicans voted for it.

If approved in the Senate and signed into law by the governor, the penalty for a first-time possession of a half ounce or less would be $150. State Rep. Steve Stafstrom, D-Bridgeport, co-chairman of the legislative Judiciary Committee, said that a number of patients with behavioral health issues, including substance abuse, can benefit from the use of the drug, also called “magic mushrooms” or psychedelic mushrooms. But the research, much being done at Yale University, is moving slowly because of the illegality of the drug.

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New York’s Heavy Hand Keeps Illegal Marijuana and Tobacco Dealers in Business

While I have fond memories of life in New York, many of them involve defying some stupid rule or regulation. It’s a pleasure to now live in Arizona where government, while still idiotic, generally has a lighter touch. Unfortunately for friends and family I left behind, Empire State officialdom still hasn’t learned its lessons, as evidenced by the heavy regulatory hand stifling sort-of-legalized marijuana, and proposals to similarly reinforce the black market with an outright ban on cigarette sales.

“Governor Kathy Hochul today signed new legislation to increase civil and tax penalties for the unlicensed and illicit sale of cannabis in New York as part of the FY 2024 Budget,” the New York governor’s office announced this week. “The legislation, first proposed by the Governor in March, provides additional enforcement power to the Office of Cannabis Management and the Department of Taxation and Finance to enforce the new regulatory requirements and close stores engaged in the illegal sale of cannabis.”

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Healthcare Non-Profit Supplies L.A. Homeless With Government-Funded Meth Pipes

Los Angeles nonprofit workers passed out boxes of government-funded crystal meth pipes to the homeless population living on Skid Row, allegedly assuming it helps prevent fatal drug overdoses.

Bodycam footage reported by local media shows workers from the Homeless Health Care Los Angeles nonprofit organization distributing the drug paraphernalia while driving around the neighborhood in a golf cart, which witnesses said only enables addicts.

“If you walk down Skid Row and see the people that are on methamphetamine … and got sores all over their body, their teeth falling out, bumps all over their face, running down the street butt naked, that’s no safety,” Tony Anthony, resident, told Fox 11 Los Angeles. “They don’t need to be coming down here passing out these glass pipes.”

The news outlet reported that the nonprofit’s executive director turned down an interview and has yet to issue a statement.

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Ohio State receives first-ever DEA license to grow psychedelic mushrooms for research

Ohio State University is about to grow psychedelic mushrooms.

For scientific research, people.

Ohio State, alongside the mental health and wellness research and development company Inner State Inc., was awarded the first-ever license by the U.S. Drug Enforcement Agency to grow whole psilocybin mushrooms. The mushrooms will be used in the study of mental health treatment capabilities with naturally grown psychedelic mushrooms.

“This license is a major milestone not only for Inner State and Ohio State, but for the entire field of psychedelic research,” Inner State CEO Ashley Walsh said Wednesday in a news release.

The license allows Ohio State and Inner State to cultivate psilocybin mushrooms for research purposes only. All research will be conducted in a federally sanctioned and secured grow house in accordance with strict DEA regulations and guidelines.

“By combining cutting-edge techniques in genomics and metabolomics, we have the opportunity to obtain a high-resolution picture of the chemical diversity of mushrooms that have remained difficult to study for several decades,” according to Ohio State researchers Dr. Jason Slot and Dr. Kou-San Ju.

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Magic mushroom guides in Oregon face uncertain trip ahead

In the last few weeks, dozens of students have graduated from schools in Oregon where they were trained to guide people through magic mushroom trips that can last as long as six hours. At one school, an alpaca farmer, a social worker, an ER nurse and a nutritionist were all in the same class, attempting to learn the tricks of a new trade. 

But it will be a few months until any of them can legally practice what they’ve learned in their state — and once they can, there are open questions about how the psychedelics industry will shape up there.  

“Our big mantra to students is, don’t quit your day job,” said Nathan Howard, the director of one facilitator school called InnerTrek, adding, “Yet.” 

The Oregon state government and 22 training schools are writing the rule book on the best strategy for administering a drug that has shown promise in clinical trials in combatting depressionaddiction or dependencies, and anxiety around terminal illnesses.  

 he first licensed magic mushroom guides could be a model for a new sort of health care professional — but are they ready for the realities of the work and how much of a risk are the new guides taking on?  

In November 2020, Oregon voters became the first in the country to approve therapeutic use of psilocybin, which is the key ingredient in magic mushrooms. The drug became legal Jan. 1, 2023, though actual sale of the psychedelic can’t begin until the state gives its stamp of approval to laboratories which will produce the psilocybin products and service centers where they’ll be consumed. Unlike cannabis, magic mushrooms won’t be sold at dispensaries and can only be used under supervision at licensed locations. 

By state law, the supervisors or psilocybin facilitators have to be over 21, have a minimum of a high school education, and they must graduate from a training school before they take a licensing exam. Beyond that, the state entrusts school administrators to vet people through the application process and to iron out the specifics of what a day on the job might entail.  

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Mushrooms Could Offer Improvements to Color Blindness, Study Suggests

The study on color blindness, which comes via researchers with the Department of Psychiatry and Psychology, Center for Behavioral Health, Neurological Institute at the Cleveland Clinic in Ohio, was published in Drug Science, Policy and Law.

According to Medical Xpress, the researchers behind the study “highlight some implications surrounding a single reported vision improvement self-study by a colleague and cite other previous reports, illustrating a need to understand better how these psychedelics could be used in therapeutic settings.”

Medical Xpress has more on the findings:

“In the current case, a subject with red-green CVD (mild deuteranomalia) self-administered the Ishihara Test to quantify the degree and duration of color vision improvement after using 5 g of dried psilocybin magic mushrooms. Self-reported Ishihara Test data from the subject revealed partial improvement in CVD, peaking at 8 days and persisting for at least 16 days post-psilocybin administration…Before mushroom ingestion, the subject self-administered the Ishihara Test, a series of graphics composed of a mosaic of dots varying in color, hue and size. The cards of the test are designed to hide test images from someone with color blindness that would be clearly visible to someone with color vision. For example, a graphic of red and green dots might have the number ‘3’ composed of only red dots, clearly apparent to most but invisible to the color-blind individual. During this baseline test, the subject reported scoring 14 on plates 1–21, indicating mild red-green blindness, with an additional set of four cards indicating deuteranomalia, a version of CVD that makes greens look more [like] reds. While the subject reported intensification of colors under the acute effects of psilocybin, the score showed only slight improvement to 15 at 12 hours post-administration. By 24 hours post-mushroom administration, the score reached 18, one above the cut-off of 17 required by the Ishihara Test for the classification of normal color vision. The score peaked at 19 on day eight and was still tuned into the range of normal vision four months later.” 

Findings like that have encouraged medical researchers, and forced lawmakers to reconsider longstanding prohibitions on magic mushrooms. 

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This California Bill Would Mandate Punishment of Marijuana Debtors Without a Hearing

California’s cannabis industry, which includes state-licensed growers, manufacturers, testing companies, distributors, retailers, and event organizers, has a deadbeat problem. In a business that generated $5.3 billion in sales last year, bills for marijuana products and services frequently go unpaid, leaving creditors in the lurch and compounding the financial difficulties created by federal prohibition.

According to an estimate cited by Assembly Member Phil Ting (D–San Francisco), “the unpaid debt bubble is over $600 million across California’s supply chain.” But Ting’s solution—a bill that would inject state regulators into debt disputes between marijuana businesses—could create new problems by interfering with freedom of contract and penalizing licensees without due process.

A.B. 766, which Ting introduced in March, would require cannabis licensees to pay bills for goods or services totaling $5,000 or more within 15 days of the final date listed on the invoice. That date could be no more than 30 days after the goods were delivered or the services were performed.

When a buyer misses that state-prescribed deadline, the seller would be required to file a report with the California Department of Cannabis Control (DCC). The DCC would then be required to notify the buyer of the violation and “commence a disciplinary action,” which could lead to suspension or revocation of his license if he fails to “pay the outstanding invoice in full” within 30 days of the notice. In the meantime, the buyer would not be allowed to “purchase goods or services from another licensee on credit.”

Griffen Thorne, an attorney at the Los Angeles office of Harris Bricken, a firm that specializes in cannabis law, says the problem that Ting describes is real. But Thorne is troubled by the implications of dictating contract terms, requiring businesses to report collection issues, and imposing a penalty based on nothing more than a report, which might be based on disputed facts.

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