A new federally funded study has found that marijuana is “significantly” associated with reduced opioid cravings for people using them without a prescription, suggesting that expanding access to legal cannabis could provide more people with a safer substitute.
Researchers at the British Columbia Centre on Substance Use and UCLA surveyed 205 people who use cannabis and opioids without a prescription from December 2019 to November 2021, aiming to test the theory that marijuana represents an effective harm reduction tool amid the overdose crisis.
The study, published in the International Journal of Drug Policy, found that 58 percent of participants reported that their motivation to use marijuana was to reduce opioid cravings. And a multivariable analysis showed that cannabis use “was significantly associated with self-reported reductions in opioid use.”
The researchers said that, to their knowledge, this represents the first study of its kind to specifically investigate “outcomes of intentional cannabis use to manage opioid cravings” among those who are using painkillers that they may be getting from the illicit market, which comes with a risk of obtaining contaminated products.
“These findings indicate that cannabis use to manage opioid cravings is a prevalent motivation for cannabis use among [people who use unregulated opioids] and is associated with self-assessed reductions in opioid use during periods of cannabis use,” the study authors wrote. “Increasing the accessibility of cannabis products for therapeutic use may be a useful supplementary strategy to mitigate exposure to unregulated opioids and associated harm during the ongoing drug toxicity crisis.”
The U.S. National Institutes of Health (NIH) and Canadian Institutes of Health Research (CIHR) provided funding for the study. One of the seven study authors disclosed that he has professorship backed by the cannabis company Canopy Growth to research marijuana science at the University of British Columbia.
This is one of the latest pieces of research in a large pool of scientific literature suggesting that marijuana can serve as a substitute for both legal and illegal substances and prescription drugs.
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