Chinese scientists claim to have engineered the world’s first mouse with fully reprogrammed genes

Researchers from the Chinese Academy of Sciences (CAS) claim to have found a novel technique for programmable chromosome fusion successfully producing mice with genetic changes “that occur on a million-year evolutionary scale” in the laboratory.

The findings could shed light on how chromosome rearrangements—the tidy packages of organized genes provided in equal numbers by each parent, which align and trade or blend traits to produce offspring—influence evolution, reported Phys.org on Thursday.

“The laboratory house mouse has maintained a standard 40-chromosome karyotype—or the full picture of an organism’s chromosomes—after more than 100 years of artificial breeding,” said Li Zhikun, a researcher at CAS’s Institute of Zoology.

“Over longer time scales, however, karyotype changes caused by chromosome rearrangements are common. Rodents have 3.2 to 3.5 rearrangements per million years, whereas primates have 1.6,” added Li, co-first author of the study.

The mouse, known as Xiao Zhu, or “Little Bamboo,” was the world’s first mammal with fully reprogrammed genes, according to the South China Morning Post.

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Author: HP McLovincraft

Seeker of rabbit holes. Pessimist. Libertine. Contrarian. Your huckleberry. Possibly true tales of sanity-blasting horror also known as abject reality. Prepare yourself. Veteran of a thousand psychic wars. I have seen the fnords. Deplatformed on Tumblr and Twitter.

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