Psilocybin Health Benefits and Magic Mushrooms Microdosing Guide

Psilocybin is a naturally occurring psychedelic substance that can be found in a variety of different mushrooms, commonly referred to as “magic mushrooms.” Psilocybin is known to possess a spectrum of psychoactive properties, and has remained a part of medicinal and shamanistic culture around the world for thousands of years.

Cutting edge modern medical research into the various properties, health benefits, and applications of psilocybin, however, has revealed that there are many use cases for this unique biological compound outside of recreational use.

Psilocybin has recently been demonstrated in multiple clinical trials to function as an effective therapeutic aid in treating a wide variety of health disorders, including assisting with the management of depression, helping to deal with addiction, PTSD, and OCD, as well as promoting the growth of brain cells and even helping to manage the symptoms of cancer and terminal illnesses.

In this guide, we will break down the basics of psilocybin, where it comes from, and how it works, as well as proceeding to present and assess the clinical evidence that supports the therapeutic and health applications of this unique compound. Lastly, we’ll examine the potential benefits of psilocybin microdosing, a novel use of psychedelics that has been demonstrated to deliver a broad range of advantages.

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DC journos are taking shrooms for ‘performance-enhancing brain boost,’ report says

Many journalists in Washington, D.C. are taking small doses of psychedelic mushrooms to improve their performance, according to Politico.

A 2020 D.C. ballot initiative made enforcement of bans on the purchase and distribution of psychedelic mushrooms the lowest priority of law enforcement, making the substance “basically legal,” according to Politico. The substance is used recreationally in full doses as well as in smaller “microdoses,” which some believe can improve brain function.

“Microdosing mushrooms as a kind of performance-enhancing brain boost — already wildly popular among the California tech set — is now fairly common in Washington, especially in media circles,” the Politico article said.

Additionally, many journalists are “macrodosing,” or taking large quantities of mushrooms to experience a psychedelic trip, as well.

Some journalists questioned the author’s claim that microdosing was common is Washington media circles.

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Microdosing Magic Mushrooms A ‘Growing Trend’ Among Some Suburban Moms

Magic mushrooms have long been considered a serious drug — the federal government puts it in the same class as heroin — but it’s catching on in the oddest place: suburbia.

Moms in communities around San Diego are “microdosing” mushrooms, which contain the mind-altering substance psilocybin, a new report says.

“It’s so necessary for some of us to be out and forward because we need to move the needle. We need to help give permission to other mothers, to fathers and other families,” said a woman identified only as Mikaela, according to the local CBS affiliate, which published a story headlined “Micro-dosing magic mushrooms: A growing trend among San Diego moms.”

In microdosing, people take a small dose in various forms, which can be pills, gummies, and chocolate. “So a dose that would give you a classic psychedelic effect would be anywhere between a gram to five, six, seven grams and so a microdose is a fraction of a gram,” Mikaela told the station.

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These Mormons Have Found a New Faith — in Magic Mushrooms

On a Sunday afternoon in March, a group of 30 strangers huddle under a park pavilion in Salt Lake City, Utah, sipping hot cocoa and shaking hands shyly as snow clots the cottonwoods. A clean-cut gang of mostly white professionals, they are united by their interest in the Divine Assembly, a two-year old church with 3,000 members that considers psilocybin its holy sacrament. 

The church’s co-founders, husband and wife Steve and Sara Urquhart, mingle quietly with the psychedelic-curious, many of whom are either new to tripping or considering their maiden voyage. Steve sticks to the sidelines, every so often reaching to smooth a conical white beard that, combined with his blue eyes and bearlike frame, make him look like a punk Santa Claus. The long beard is the only outer marker of his new identity: Before pivoting to mushroom churches, Urquhart was one of the most powerful Republicans in the Utah State Legislature, serving from 2001 to 2016, with a stint as majority whip in the House before eventually moving over to the Senate. Former colleagues and friends recall his small-government brand of Republicanism as “rock-ribbed.” He was also, like more than 60 percent of Utah and approximately 86 percent of the Legislature in 2021, deeply, devoutly Mormon. 

“We were all the way in,” Urqhuart says of the proudly peculiar American religion with about 6.7 million adherents in the U.S. and about 16.6 million globally. Founded by Joseph Smith in 1830 during the Second Great Awakening in upstate New York, Mormonism (or the Church of Jesus Christ of Latter-day Saints, as church authorities requested it be called in 2018, though many Latter-day Saints, or Saints for short, still use the term “Mormon”) bases its teachings on the revelations of Smith, whom they consider a prophet. According to Smith, who claimed to have translated the Book of Mormon from a pair of gold plates inscribed with “reformed Egyptian,” Latter-day Saints are God’s chosen people destined to restore the original Christian gospel — a gospel that included, they professed up until 1890, polygamy. 

“I knew all the secret handshakes,” Urquhart later divulges after one shot of tequila, and he means it quite literally, demonstrating a dizzying pattern of grips, bumps, and daps that look straight out of a Monty Python skit. 

In all likelihood, Urquhart and others believe now, Smith lifted those handshakes and many other ceremonial elements from the Freemasons, the then-popular secret society that counted Smith as a member. Urquhart also believes, 100 percent seriously, that the LDS Church (the mainstream one he and Mitt Romney are from, not the fundamentalist offshoots depicted in Under the Banner of Heaven) is a cult. Specifically, he says, alluding to the church’s polygamist history and fact that some bishops still ask teens if they are masturbating, “a sex cult with really bad sex.”

Church or cult, Urquhart crashed out of it around 2008. In the park that Sunday, he is in good company. Although the Divine Assembly is not limited to former LDS members, or “post-Mormons” as they refer to themselves, the majority of the crowd by default is, and they’re aching for a new kind of spirituality to fill the void. One couple, Yesenia and Guillermo Ramos, tell me they left the LDS Church in 2012, after it began to feel like the opposite of what they thought it stood for. “God is love,” Yesenia says with conviction, but within the church, she says she felt judged for her decision to be both a mom and a nurse, rather than a stay-at-home mom. Furthermore, Yesenia says, she was sick of the pressure to appear perfect all the time, a common complaint among LDS women that Dr. Curtis Canning, president of the Utah Psychiatric Association, has called “Mother of Zion Syndrome.”

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How an NHL Enforcer Broke His Body — and Turned to Psychedelics to Heal His Brain

Riley Cote’s journey to enlightenment began in earnest when a hulking man punched him in the face. Cote, now 40 and retired from professional hockey, remembers the moment with a dark laugh. He’d gotten into this particular bust-up one night during the 2009 season with one of the NHL’s most vicious fighters, and took the worst of it, waking the next day with his left eye blackened shut.

“What,” he asked himself, “am I doing?”

He drove to the Philadelphia Flyers training facility and got into the shower. Feeling congested, he reached for a tissue. He didn’t realize he’d suffered a cracked sinus, so what happened next was physics. When he blew his nose, the air — rather than coming out of his nostrils — inflated his face. The pressure surged instantly behind his good eye and closed it tight.

Team trainer Derek Settlemyre heard Cote scream. “His whole face had swollen up,” Settlemyre recalls. “We tell them, if they think they have a fracture, ‘Don’t blow your nose’ — and he did.”

After eight years in pro hockey (four in the NHL, four hopping around its minor-league teams), Cote felt his retirement bearing down. As an NHL “enforcer” — a player whose main role is to get into fights — he’d taken countless hits on the ice. Off it, he self-medicated with booze and drugs. He’d brutalized his body inside and out by the tender age of 28. “I damaged my brain,” Cote says. “Punching it and dehydrating it and partying my ass off.”

Today, Cote is a new man, with a mane of long brown hair, a yoga-trimmed physique, and an aura of ease in his own skin. It is a transformation he credits largely to psychedelic drugs. Since retiring, Cote has emerged as one of the sports world’s most vocal advocates for what he calls “plant medicines” — from cannabis, itself a light psychedelic, to weightier hallucinogens including DMT and magic mushrooms — to treat post-concussion symptoms (think headaches, insomnia, depression, and possibly, the degenerative brain condition known as chronic traumatic encephalopathy, or CTE). In 2017, Cote co-founded Athletes for Care, a group that promotes research into the physical and emotional health issues athletes face and novel paths for treatment. He regularly speaks at conferences on the benefits of psychedelics. And, perhaps most important, he reaches out to players who are known to be struggling post-career, even arranging magic-mushroom ceremonies where they can safely experiment with the drug.

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The Emerging Magic Mushroom Monopoly

In December 2017, one of the godfathers of the contemporary psychedelic renaissance, Bob Jesse, penned a manifesto for the commercial era of hallucinogens, one that echoed as far and wide as when Timothy Leary famously evangelized, “Turn on, tune in, drop out,” in 1966. Jesse delivered a very different kind of message: “Open science for all!”

A philanthropist and independent researcher, Jesse was instrumental to reviving a new wave of medical interest into psychedelic-assisted therapy starting in the 1990s. This new form of therapy offers a revolutionary approach to treating the rising cases of depression and anxiety in the U.S. But Jesse began to see this pioneering research pillaged by Big Pharma, as soon as it showed commercial value as a breakthrough treatment for mental illness.

In the manifesto, Jesse took a stand against would-be monopolists for flagrantly misusing patent laws, advocating instead for a shared creative commons for psychedelic research, with limited intellectual-property rights. The statement attracted over 100 co-signers, including every major figure in the psychedelic research and NGO community, from philanthropic funders to grassroots advocates.

But there was a notable absence from the list: the founders of Compass Pathways, a rapidly growing psychedelic therapy company bankrolled by major investors, notably Peter Thiel, the PayPal co-founder and right-wing political financier.

“It was very suspicious when they didn’t sign on to the letter. It gave a lot of people pause about what their plans were,” said Carey Turnbull, a longtime philanthropist in the psychedelic community who has become one of Compass Pathways’ main detractors.

Compass’s founders—millionaire couple George Goldsmith and Ekaterina Malievskaia—had already raised eyebrows by quietly transitioning from a charity organization to a for-profit corporation in 2017. Compass was also conducting dubious drug trials on the Isle of Man, an infamous tax haven for the uber-wealthy with lax regulatory oversight. Suspicions abounded about the unusually restrictive contracts it pushed researchers to sign, and reports that Compass had blocked other organizations from signing a deal with one of their drug manufacturers.

The unwillingness to sign the letter was more than a snub. It was a harbinger of things to come.

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The human brain doubled in power, very suddenly, 200,000 years ago. Why?

There seems to have been a profound difference in cognitive abilities between early Homo sapiens and our immediate predecessor, Homo erectus. Sure, erectus stood upright — a big, um, step forward — but with the emergence of Homo sapiens, we see traces of art, pictography, and tool usage, and we believe humankind made its first forays into language.

In the early 1990s, psychedelic advocate and ethnobotanist Terence McKenna published his book Food of the Gods in which he surmised that homo sapiens’ cognitive leap forward was due to their discovery of magic mushrooms. The scientific community never took McKenna’s theory very seriously, considering it mostly trippy speculation — these days, his ideas have largely been relegated to the spacier corners of Reddit. Now, however, the idea has acquired a new advocate, psilocybin mycologist Paul Stamets, who’s suggesting McKenna was right all along.

In McKenna’s Stoned Ape hypothesis,” he posited that as humans began to migrate to new areas, at some point they came upon psychedelic mushrooms growing in cow droppings, as is their wont, and then ate them. After ingesting them, and more specifically the psilocybin they contained, their brains kicked into overdrive, acquiring new information-processing capabilities, and a mind-blowing expansion of our imaginations in the bargain. Many modern users of psychedelics claim the world never looks the same again after such an experience. As McKenna put it, “Homo sapiens ate our way to a higher consciousness,” and, “It was at this time that religious ritual, calendar making, and natural magic came into their own.”

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WHERE CAN YOU LEGALLY TAKE MAGIC MUSHROOMS? LIST OF REGIONS AND COUNTRIES

The chemical in magic mushrooms that gives it the “magic” is known as psilocybin. This compound or some form of it is found in approximately 180 species of mushroom. But these hallucinogenic fungi are not new substances. Rather, they are one of the oldest substances used and recorded in humanity’s history to increase levels of consciousness. 

As such, magic mushrooms have remained among the most common and popular psychedelic substances even today. They are quite popular in South America, Europe, and North America. But, as with all psychedelic substances, there are concerns over their usage and legality, and many places prohibit these special mushrooms.

But, that mindset is changing. Studies have recently claimed that mushrooms containing psilocybin can actually help the patients in some specific cases. In a 2017 study, they were found to have some effect when it came to treating mental health conditions. This was a big step forward for advocates who wanted to legalize psilocybin mushrooms.

As for the present situation, there are a handful of countries where it is completely legal to own and use magic mushrooms. Here is a list of them according to the major regions. However, be aware that the use of these substances in most cases is still dangerous. Moreover, in some cases, the law forbids the chemical “psilocybin” while not mentioning magic mushrooms themselves, which makes it very risky. As such, we will leave out the nations where magic mushrooms are not openly sold

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Take Two Shrooms and Call Me in the Morning: The Medical Promise of Magic Mushrooms

SIX YEARS AGO, on a late fall evening, I stood in front of a pinball machine, flummoxed. The game was space themed, with an elaborate UFO in the middle surrounded by a kaleidoscope of flashing lights. I was mesmerized, but I had no idea how to make it start. The machine’s coin slot and glowing buttons were suddenly indecipherable. Time felt like it had slowed to a crawl, and I became paranoid that the handful of people in the bar were staring at me, wondering what I was doing. It was then I realized that the magic mushrooms were kicking in.

This was the first time I’d taken a hallucinogen since my early twenties. Back then, as a university student, it was a lark. Now, in my forties with a family, the idea was daunting. This trip, however, had a medical purpose: for nearly two decades, I’ve struggled with a rare illness known as cluster headaches. Cluster headaches have been described as more painful than childbirth and kidney stones; they’re sometimes referred to as “suicide headaches” because of the mental toll they take. These headaches happen in groups—for me, they occur two or three times a day for weeks on end. Like migraines, they’re difficult to treat. Over the years, I’ve visited countless neurologists, chiropractors, acupuncturists, and naturopaths. I’ve taken prescriptions and experimented with cleanses and diets. Nothing worked.

Then I stumbled onto Clusterbusters, a popular message board created by a fellow sufferer, where people around the world could swap advice. There was one tip that was gaining traction: multiple posters were reporting that, after they had consumed magic mushrooms, their headaches had abruptly—miraculously—stopped. I was in the midst of a headache cycle at the time and was desperate to stop the pain. I reached out to a long-time friend in Toronto, and not long afterward, we downed a handful of dry, fishy-tasting fungi in his newly renovated kitchen.

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Hallucinogen in ‘magic mushrooms’ relieves depression in largest clinical trial to date

Psilocybin, the hallucinogen found in “magic mushrooms,” helped to relieve symptoms in people with hard-to-treat depression in the largest clinical trial of its kind to date, the trial’s organizers announced Tuesday (Nov. 9).

Earlier this year, a small study suggested that psilocybin might work as well as the common antidepressant escitalopram (Lexapro) at relieving moderate to severe depression, and other past research has hinted at the drug’s promise, Live Science previously reported. But this new trial, conducted by the pharmaceutical company Compass Pathways, is the largest gold-standard trial of psilocybin to date, so its results could carry more weight than previous research, STAT reported

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