Moderna’s COVID-19 vaccine plasmid contains a human α-globin DNA fragment regulating blood and cardiovascular biology, and because plasmids are integration-competent DNA molecules, this fragment is capable of inserting into the human genome—precisely as blood and cardiovascular injuries like myocarditis and pericarditis emerge as the dominant serious adverse events following Moderna vaccination.
In plain terms, Moderna’s shot carries a piece of human blood gene code that can lodge itself into patient DNA, raising the possibility that the very blueprint of the vaccine is fueling the same heart and blood injuries now seen at the top of its safety reports.
While most public discussion blames the spike protein or lipid nanoparticles for Moderna’s adverse events, the evidence here points to something no one is talking about—the plasmid blueprint itself may be driving the blood and heart injuries dominating the safety signal.
A September 2025 peer-reviewed paper in Molecular Therapy: Nucleic Acids confirms that Moderna’s mRNA-1273 (Spikevax) vaccine plasmid carries a 3’ untranslated region (UTR) from the human α-globin (HBA1) gene.
- α-globin encodes part of hemoglobin, central to red blood cell stability and oxygen transport.
- Its regulation is directly tied to blood and cardiovascular function—mutations cause α-thalassemia, anemia, and cardiac stress.
- By design, Moderna’s blueprint hard-codes this human blood gene regulator into the plasmid template.
Hellbound and Down 