Mysterious New ‘Borg’ DNA Seems to Assimilate Genes From Different Organisms

Mysterious strands of DNA that seemingly assimilate genes from many different organisms in their surrounding environment have been discovered in a Californian backyard.

Scientists have named these elements “Borgs”, and their discovery could help us not just understand the evolution of microorganisms, but their interactions within their ecosystems, and their role in the broader environment.

According to geomicrobiologist Jill Banfield from the University of California, Berkeley, Borgs could make for a tremendously significant discovery.

“I haven’t been this excited about a discovery since CRISPR,” she said on Twitter. “We found something enigmatic that, like CRISPR, is associated with microbial genomes.”

A paper describing the structures has been uploaded to preprint server bioRxiv, and currently awaits peer review.

The first of the Borgs was discovered in mud dredged up from Banfield’s backyard. She was working with geneticist Basem Al-Shayeb of UC Berkeley to identify viruses that infect anoxic microbes known as archaea that live in wetland environments, Science Magazine reports.

Environmental DNA is an excellent way to identify the range of organisms that inhabit an ecosystem. But in their scoop of mud, Banfield and Al-Shayeb found something funny: a structure of DNA consisting of nearly a million base pairs. That’s huge.

A closer look at the sequence revealed even more peculiarities: more than half of the genes were new; it had mirrored sequences at the end of each strand; and it showed structures consistent with the ability to self-replicate.

Puzzled, the researchers turned to DNA databases to see if they could find anything else that looked like their discovery. They identified 19 sequences that seemed to fit the profile.

What these DNA structures are is unclear, but they’re certainly fascinating. They belong to a class of structures called extrachromosomal elements, or ECEs, which can be found outside of the chromosomes that contain most of an organism’s genetic material.

ECEs are huge and self-replicating, and they can be found inside or outside of the cell nuclei; examples include plasmids and viral DNA.

“We can neither prove that they are archaeal viruses or plasmids or mini-chromosomes, nor can we prove that they are not,” the researchers write in their paper.

The Borgs are much larger than other ECEs, however, according to Banfield: one-third of the size of their host microbes.

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Author: HP McLovincraft

Seeker of rabbit holes. Pessimist. Libertine. Contrarian. Your huckleberry. Possibly true tales of sanity-blasting horror also known as abject reality. Prepare yourself. Veteran of a thousand psychic wars. I have seen the fnords. Deplatformed on Tumblr and Twitter.

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