It has been surprisingly difficult to get an answer to a simple and highly relevant question: Is aluminium in vaccines harmful? After having studied the best evidence we have, the randomised trials, in great detail, I conclude that the answer is yes.
Like lead, aluminium is a highly neurotoxic metal. We will therefore expect vaccines containing aluminium adjuvants to cause neurological harms if the aluminium enters the nervous system in neurotoxic amounts.
The aluminium in the adjuvant is important for eliciting a strong immune response in non-live vaccines and their efficacy is related to their toxicity at the injection site.1-3 Immune-reactive cells engulf particles of aluminium adjuvant and distribute their load throughout the body, including to the brain, where they are killed, releasing their contents into the surrounding brain tissue where they can produce an inflammatory response.
The precise mechanism of action is not so important, but the data we have on the harms are, and they have been systematically distorted.
False Information from the European Medicines Agency (EMA)
In October 2016, my research group complained to the European Ombudsman about the EMA’s mishandling of their investigation into the suspected serious neurological harms of the HPV vaccines.4 In his reply to the Ombudsman, EMA’s Executive Director Guido Rasi stated that the aluminium adjuvants are safe; that their use has been established for several decades; and that the substances are defined in the European Pharmacopoeia.5,6
Rasi gave the impression that the aluminium adjuvants in the HPV vaccines are similar to those used since 1926. However, the adjuvant in Gardasil, Merck’s vaccine, is amorphous aluminium hydroxyphosphate sulfate, AlHO9PS-3 (AAHS), which has other properties than aluminium hydroxide, the substance Rasi mentioned. Moreover, its properties are not defined in the pharmacopoeia. AAHS has a confidential formula; its properties are variable from batch to batch and even within batches. The harms caused by the adjuvant are therefore likely to vary. When we investigated whether the safety of AAHS has ever been tested in comparison with an inert substance in humans, we were unable to find any evidence of this.
Rasi mentioned that the assessment of the evidence for the safety of the adjuvants had been performed over many years by the EMA and other health authorities, such as the European Food Safety Authority, the FDA, and the WHO.