According to a new study published last week in NPJ Vaccines, Japanese researchers engineered an entirely new strain of bird flu, combining the genetic material of two separate wild viruses to create what they call Vac-3: a pathogen that is “a reassortant virus between A/duck/Hokkaido/101/2004 (H5N3) and A/duck/Hokkaido/262/2004 (H6N1).”
This lab-built virus—A/duck/Hokkaido/Vac-3/2007 (H5N1)—was never observed in nature.
It was artificially assembled, grown in eggs, concentrated, and inactivated with formalin to become the whole-particle vaccine used in long-term testing on nonhuman primates.
The new study comes after NIH-funded researchers at the University of Georgia, Mount Sinai, and Texas Biomed were caught engineering lab-made H5N1 bird flu viruses—one of which killed 100% of exposed mammals—using synthetic DNA constructs and then deliberately infecting live dairy cows, all under the same $59 million federal contract that has also been tied to mammal-adapted, drug-resistant strain development.
Japan is also working with U.S. scientists on other projects to build lab-made horse-human influenza hybrids that replicate 100 times faster than natural strains using aborted fetal cells engineered with the cancer-linked SV40 virus, also under the banner of vaccine development.
All of these developments raise fears that another man-made pandemic is on the horizon, as Congress, the White House, the Department of Energy, the FBI, and the CIA have acknowledged that a lab-related incident involving gain-of-function research is most likely the origin of COVID-19.
An Engineered Virus with New Properties
The new Japanese paper highlights that this bird flu Frankenvirus triggered significantly stronger immune responses than existing flu vaccines.
It did so by retaining its full genetic structure, including viral RNA, which stimulated toll-like receptor 7 (TLR7) and a cascade of innate immune activation.
“WPVs contain single-stranded viral RNAs that stimulate innate immune receptors such as toll-like receptor 7,” the authors write.
This means the lab-built virus was left fully intact so it could shock the immune system into overdrive, triggering a much stronger reaction than normal flu shots.
Unlike conventional “split” vaccines, which separate viral proteins from RNA, Japan’s whole-particle vaccine (WPV) preserved the virus’s full anatomy.
This allowed it to activate dendritic cells, induce interferon-producing T cells, and stimulate somatic hypermutation—a powerful, but risky, rewiring of the immune system.
In short, the new virus didn’t just train the immune system—it reprogrammed it.
Hellbound and Down 