This report examines an October 2025 FOIA release from U.S. Right to Know regarding DARPA’s “Pandemic Prevention Platform (P3)” Research Description Document (RDD) from Duke University, Revision 3 (January 2020)—a program that was already operational before the COVID-19 pandemic began.
DARPA’s own words paint the clearest picture yet of a fully integrated pre-COVID pandemic U.S. military system that can:
- take only a digital sequence of a virus
- synthesize an infectious clone
- grow it in a “Thaw-and-Infect” panel of human and animal cell lines
- isolate antibodies from infected blood
- evolve those antibodies using computational mutation engines
- encode those antibodies into modified mRNA
- package them in lipid nanoparticles
- and produce 20,000 doses within 60 days
The program is open about building a platform that works even when no physical virus exists, only a computer file.
Hellbound and Down 