President Donald Trump has unveiled a sweeping action to slash the cost of the nation’s most expensive weight-loss drugs, casting it as a turning point for both healthcare affordability and economic fairness. In what the White House calls a “historic” agreement with pharmaceutical giants Eli Lilly and Novo Nordisk, the administration announced that prices for popular GLP-1 agonists (weight-loss drugs) such as Ozempic and Wegovy will drop by more than two-thirds under a new initiative known as TrumpRx. The program is a government-backed platform that allows Americans to purchase prescription drugs at discounted rates negotiated by the administration.
The measure, described by officials as one of the largest single reductions in drug prices in U.S. history, aims to make medications long seen as luxury treatments accessible to millions of Americans battling obesity and related conditions.
Applause for the move was far from unanimous. Within the “Make America Healthy Again” (MAHA) camp — the wing of the movement that believes real health starts with prevention rather than prescriptions — the mood was restrained. Critics argue that the deal hands pharmaceutical companies both market dominance and political validation, locking Americans further into a medical model driven by patented injections.
The Deal
The White House framed the deal as a landmark victory for American consumers:
The agreement represents a historic reduction in prices for Americans on the two drugs with the highest annual expenditures in the United States, both of which help adults struggling with diabetes, heart disease (Ozempic and Wegovy only), obesity, and other conditions.
Under the terms of the new arrangement, the monthly cost of Ozempic and Wegovy will fall from about $1,000 and $1,350, respectively, to $350 when purchased through TrumpRx. Prices for Eli Lilly’s Zepbound and Orforglipron, once approved, will be reduced from $1,086 to an average of $346. If — or rather when — the FDA later authorizes the Wegovy pill or similar oral GLP-1 drugs currently in development, “the initial dose of those drugs will be priced at $150 per month” through the portal.
The administration said the new pricing will allow Medicare and Medicaid to cover obesity treatments “at a dramatically lower cost to taxpayers than that proposed by the Biden Administration.” Under the agreement, Medicare will pay just $245 a month for drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound. That is less than half of prior proposals.
According to the fact sheet:
These low prices will enable Medicare to cover Wegovy and Zepbound for patients with obesity and related comorbidities for the first time.
Beneficiaries “will pay a co-pay of just $50 per month.” Plus, “state Medicaid programs will also have access to these medications at these prices.”
The deal also extends to other high-cost medicines. Eli Lilly’s Emgality, a migraine therapy, will now cost $299 per pen, down $443 from its list price. Trulicity, another diabetes treatment, will fall to $389 per month, a reduction of nearly $600. Novo Nordisk’s insulin products NovoLog and Tresiba will be capped at $35 per monthly supply.
Hellbound and Down 