Medicine saves lives every day, combating everything from infections to chronic pain. But the little-discussed reality is that adverse drug reactions are the third leading cause of death in the US, claiming over 250,000 lives annually.
Even more insidious, side effects can emerge months or years after starting—or stopping—a medication, long after you’ve forgotten about it, as seen with delayed tendon damage from antibiotics or bone issues from osteoporosis drugs.
These delayed reactions highlight how drugs can ripple through the body in unexpected ways, affecting organs and systems far beyond their intended target.
From hormonal havoc to bizarre behavioral shifts, here are 50 peculiar side effects that remind us: while medicine helps, it can also unleash chaos we never saw coming.