A class of drugs commonly used to treat movement disorders like Parkinson’s disease and restless leg syndrome is pushing people into risky sexual behavior.
Patients taking dopamine agonists say the drugs have triggered uncontrollable impulses, including flashing, sex addiction and even pedophilia — leaving them struggling with feelings of shame and confusion.
Reports reviewed by the BBC suggest drugmaker GSK has known about the risk of so-called “deviant” sexual behavior since 2003, yet patients claim their doctors continue to fail to warn them about these potentially devastating side effects.
Dopamine agonists mimic dopamine, a key brain chemical that controls movement and is activated by pleasure. However, these drugs can overstimulate feelings of pleasure while dulling the brain’s ability to recognize the consequences of our actions.
This can lead to impulse control disorders, with studies showing 13% to 24% of Parkinson’s patients on dopamine agonists develop them. While a warning about these risky behaviors is listed alongside common side effects like nausea and insomnia, research suggests they often go unnoticed or undiagnosed.
In the US, the American Academy of Sleep Medicine recommends the drugs only be used for short-term treatment, such as end-of-life care.