Psilocybin, the hallucinogen found in “magic mushrooms,” helped to relieve symptoms in people with hard-to-treat depression in the largest clinical trial of its kind to date, the trial’s organizers announced Tuesday (Nov. 9).
Earlier this year, a small study suggested that psilocybin might work as well as the common antidepressant escitalopram (Lexapro) at relieving moderate to severe depression, and other past research has hinted at the drug’s promise, Live Science previously reported. But this new trial, conducted by the pharmaceutical company Compass Pathways, is the largest gold-standard trial of psilocybin to date, so its results could carry more weight than previous research, STAT reported.